A brief screening examination should be conducted checking the face, eyes, mouth, chest, abdomen, spine and limbs to exclude major abnormalities. A strong cry and a widespread pink blush over the face and body are good signs that all is well. Some children may be born with ambiguous genitalia. Ambiguous genitalia is a medical emergency and requires urgent assessment by a paediatrician. If you have sufficient clinical experience, an orogastric tube should be passed when the neonate's mother has suffered polyhydramnios. This excludes oesophageal atresia.

Enema how to apply Animation

Anatomy of Love

Cisplatin is in a class of drugs known as platinum-containing compounds used to treat various types of cancers including metastatic testicular and ovarian tumors. The molecule was first discovered in 1845, but did not receive FDA approval until 1978. Today it is known as the "penicillin of cancer drugs," because it is so effective for many different cancers. There are three key players involved in Cisplatin's mechanism: (1) Cisplatin, (2) DNA (3) and an HMG Protein. Most Cisplatin enters the body through active transport, but some molecules are passively defused through the cell membrane. Once in the nucleus, Cisplatin can form an adduct with two consecutive guanine bases within a strand of DNA. The molecule loses its chlorine atoms in exchange for the nitrogen atoms of the target guanines. Cisplatin can bond more tightly with nitrogen because nitrogen balances the platinum charge more effectively than chlorine. It is this adduct-induced DNA bend that allows binding of proteins which contain the high mobility group, HMG domain. Once the protein is bound to the DNA, it inserts a wedge-like phenyl group of phenylalanine 37 into the widened minor groove created by the bend. The tightly bound HMG protein causes destacking of the nucleotide bases, resulting in the DNA helix becoming kinked. In this way, Cisplatin can be thought of as a monkey wrench in the DNA repair system. With the HMG protein bound to the DNA, the modified strand is not repaired properly and so the cell dies. The success of Cisplatin depends on its ratio of efficacy between cancerous and healthy cells.

USMLE Step 2 CS - DIARRHEA - This is just preview video. To get full access please visit our website : www.usmletutoring.com

Watch that Female Genital Walls Tightening Plastic Surgery

This is an example of a surgery to fix a femur (thigh bone) fracture utilizing an intramedullary nail. This is a minimally invasive way of fixing this surgical problem and allows for immediate range of motion and full weight-bearing.

Wilms tumor, also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children, rarely in adults. It is named after Dr. Max Wilms, the German surgeon (1867–1918) who first described it. Approximately 500 cases are diagnosed in the U.S. annually.

Female Foley Catheterization Technique

Here's how female-to-male gender reassignment surgery works.

Tears Of Abortion - Story of an aborted baby,

Histology of Hyaline Cartilage

Trigger finger, also known as stenosing tenosynovitis (stuh-NO-sing ten-o-sin-o-VIE-tis), is a condition in which one of your fingers gets stuck in a bent position. Your finger may straighten with a snap — like a trigger being pulled and released. Trigger finger occurs when inflammation narrows the space within the sheath that surrounds the tendon in the affected finger. If trigger finger is severe, your finger may become locked in a bent position. People whose work or hobbies require repetitive gripping actions are at higher risk of developing trigger finger. The condition is also more common in women and in anyone with diabetes. Treatment of trigger finger varies depending on the severity.

Clinical case discussion for exams.
Useful for medical students and others.

This Animation is strictly made in accordance to Snake Bite Treatment Guidelines and Protocols

Rotator cuff pain commonly causes local swelling and tenderness in the front of the shoulder. You may have pain and stiffness when you lift your arm. There may also be pain when the arm is lowered from an elevated position. Beginning symptoms may be mild. Patients frequently do not seek treatment at an early stage. These symptoms may include: Minor pain that is present both with activity and at rest Pain radiating from the front of the shoulder to the side of the arm Sudden pain with lifting and reaching movements Athletes in overhead sports may have pain when throwing or serving a tennis ball As the problem progresses, the symptoms increase: Pain at night Loss of strength and motion Difficulty doing activities that place the arm behind the back, such as buttoning or zippering If the pain comes on suddenly, the shoulder may be severely tender. All movement may be limited and painful.

Most women have vaginal discharge at many different times throughout their cycle. During ovulation, white and watery discharge is common and accepted as normal. But, discharge after ovulation is widely believed to be a sign of pregnancy.

Tonsil Stones Caseum

Loyola oral Presentation for Rounds video

Treatment may include: Rest. Ice or heat. Nonsteroidal anti-inflammatory medications. Strengthening exercises. Ultrasound therapy. Corticosteroid injection. Surgery (for severe injuries)