Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading to inhibition of DNA synthesis and inhibition of cellular replication. The mechanism involved in its activity against rheumatoid arthritis is not known.

Watch that video of People should have gone to the dentist a lot sooner

The term labiaplasty refers to a procedure that reduces the length of the labia minora. It is the most commonly performed female genital plastic surgery procedure and it can relieve symptoms women experience from twisting and tugging of the labia. Women opt for surgery for a variety of reasons, including pain from twisting and tugging of the labia when riding a bike or during intercourse, itching and irritation, and self-consciousness.

How to Teach Kids to Safely Lift, Carry and Move Heavy Objects

he inflatable penile prosthesis consists of two attached cylinders -- a reservoir and a pump -- which are placed surgically in the body. The two cylinders are inserted in the penis and connected by tubing to a separate reservoir of saline. The reservoir is implanted under the rectus muscles in the lower abdomen.

Female to Male gender confirming top surgery video : "Double Incision" Technique.

Functional endoscopic sinus surgery is a minimally invasive surgical treatment which uses nasal endoscopes to enlarge the nasal drainage pathways of the paranasal sinuses to improve sinus ventilation.

Pivot Shift test to confirm ACL Injury

A video discussing the importance of following up the blood pressure for diabetic patients and the serious complications that they can avoid by this very simple measure.

As more couples explore anal sex, understanding the risks, rewards, and proper strategy is important. Here's what you need to know about safety and more.

Gynecological Examination

The examination of the groin, hernial orifices and male external genitalia are clinical examinations which undergraduate medical students are commonly less confident about performing competently, due to the lack of clinical exposure.

A great video showing the multiple presentations of the baby which the doctor may encounter while delivery like breech presentation..etc

CORRECTION: After review of this video, it is clear that this video is of a baby who is near full term (40 weeks) based on the size. Late trimester "abortions" are defined only to viability of a baby (24 weeks) A 24 week baby is much smaller than this baby shown and by definition this is not a late "abortion" procedure. The proper labeling of this video should be management of a deceased breech baby with "head entrapment" as this was almost certainly a naturally occuring delivery and an OB nightmare (Reviewed by Dr. Frederick Bright)

Force Does It Take To Break A Bone

A report of Female Genital Mutilationn FGM (female circucision) in Menya In Egypt تقرير من مدينة المنيا في صعيد مصر عن ختان لاناث

HIV gradually destroys the immune system by attacking and killing a type of white blood cell called a CD4 cell. CD4 cells play a major role in protecting the body from infection. HIV uses the machinery of the CD4 cells to multiply (make copies of itself) and spread throughout the body. This process, which is carried out in seven steps or stages, is called the HIV life cycle. HIV medicines protect the immune system by blocking HIV at different stages of the HIV life cycle. Antiretroviral therapy or ART is the use of HIV medicines to treat HIV infection. People on ART take a combination of HIV medicines from at least two different HIV drug classes every day. Because each class of drugs is designed to target a specific step in the HIV life cycle, ART is very effective at preventing HIV from multiplying. ART also reduces the risk of HIV drug resistance. ART can’t cure HIV, but HIV medicines help people with HIV live longer, healthier lives. ART also reduces the risk of HIV transmission (the spread of HIV to others).

The products of a surgical abortion.