Aplastic anemia is a hematopoietic disorder caused due to T lymphocyte mediated destruction of stem cells resulting in pancytopenia with a cellular bone marrow and normal cell cytogenetics. The causes of aplastic anaemia may be inherited or acquired. The causes and the diagnostic approach, along with spectrum of severity of this disorder is discussed in this presentation. A detailed discussion of the management options, along with pharmacological therapy and supportive therapy in these cases is also discussed. The treatment options include, in addition to a stem cell transplant, anti-thymocyte globulin, cyclosporine, methyprednisolone and eltrombopag (for patients who have failed treatment on combined modality therapy with ATG and cyclosporine)

Know About Cardiothoracic Surgery in 60 Seconds About what cardiothoracic surgery is, why it is done and what is the result of such surgery. A Major Session on #cardiothoracic #surgery at #Congress #2018HCC 2018 Healthcare and Cardiology Conference #BANGKOK http://cosmicseries.org/cardiology-conferences/

Few facts and information are summed up in this short video related to Mental Health, Psychiatry and Depression.

Explained (Balloon Sinuplasty and Endoscopic Sinus Surgery)

Detroit Medical Center commercial for Electronic Medical Record - DMC is the only healthcare system in Michigan with 100% medication scanning - a huge leap forward in patient safety. ~ Detroit Medical Center

Anterior Cruciate Ligament Reconstruction

Continuous Suture

Cricothyroidotomy Video

The liver also detoxifies chemicals and metabolizes drugs. As it does so, the liver secretes bile that ends up back in the intestines. The liver also makes proteins important for blood clotting and other functions. First, for those impatient, short answers to the mini-questions (if you're reading this in the news feed, you may want to click through for the question details): No one knows why we evolved 2 kidneys and one liver.

It depends upon which ligament is injured. If it is medial collateral ligament you feel pain when you walk ,sit and stand and you will be liming as well. If it is anterior cruciate ligament you feel pain when you walk on uneven ground.

It involves placing a small, expandable tube called a stent in the narrowed artery. This procedure is also called carotid angioplasty and stenting. There are two carotid arteries-one on each side of the neck-that supply blood to the brain. These arteries can be narrowed and damaged by fatty deposits called plaque.

A video discussing Causes of Itching in the Vulva

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Body Bizarre is a TLC show with a name I'm not too wild about, but with stories that are nonetheless fascinating. Today we look at separating conjoined twins, a girl with ants crawling out of her ears, a man who nearly lost his hand in a factory accident, a family that all has 6 fingers, and more.

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What is tropical sprue? Tropical sprue is diagnosed when somebody has long-standing GI problems and has visited tropical regions in the past. It's thought to be caused by bacterial overgrowth and often leads to villous atrophy.

Learn one of the hidden reasons why you still have a thyroid symptoms. If your lab results are "normal"--then why do you still have thyroid symptoms like: * Tired, sluggish * Can't lose weight even with exercise * Feel cold—hands, feet, or all over * Require excessive amounts of sleep to function properly * Increase in weight gain even with low-calorie diet * Gain weight easily * Difficult, infrequent bowel movements * Depression, lack of motivation * Morning headaches that wear off as the day progresses * Outer third of eyebrow thins * Thinning of hair on scalp, face or genitals or hair loss * Dryness of skin and/or scalp * Mental sluggishness * Nervousness and emotional * Insomnia * Night sweats

This tutorial explains the difference in mechanisms between the 2 palsies. Bulbar palsy is a lower motor neuron condition and pseudobulbar palsy is an upper motor neuron condidtion.

Histology of Dense Regular Connective Tissue

Has your dentist or endodontist told you that you need root canal treatment? If so, you're not alone. Millions of teeth are treated and saved each year with root canal, or endodontic, treatment. Remember, root canal treatment doesn't cause pain, it relieves it. Watch our videos below to learn more! Inside the tooth, under the white enamel and a hard layer called the dentin, is a soft tissue called the pulp. The pulp contains blood vessels, nerves and connective tissue, and helps to grow the root of your tooth during development. In a fully developed tooth, the tooth can survive without the pulp because the tooth continues to be nourished by the tissues surrounding it.

Severe combined immunodeficiency (SCID) is a life-threatening syndrome of recurrent infections, diarrhea, dermatitis, and failure to thrive. It is the prototype of the primary immunodeficiency diseases and is caused by numerous molecular defects that lead to severe compromise in the number and function of T cells, B cells, and occasionally natural killer (NK) cells. Clinically, most patients present before age 3 months. Without intervention, SCID usually results in severe infection and death in children by age 2 years. A committee of experts, initially sponsored by the World Health Organization (WHO), meets every 2 years with the goal to classify the group of primary immunodeficiency diseases according to current understanding of the pathways that become defective in the immune system.[1] Eight classification groups have been determined, with SCID being one of the best studied. Over the past few decades, the diverse molecular genetic causes of SCID have been identified with progress from studies of the immune system.[2] SCID is considered a pediatric emergency because survival depends on expeditious stem cell reconstitution, usually by bone marrow transplantation (BMT). Appropriate diagnosis is essential because instituting proper treatment is lifesaving. Despite the heterogeneity in the pathogenesis of immune defects, common cutaneous manifestations and typical infections can provide clinical clues in diagnosing this pediatric emergency.[3] Skin manifestations were prevalent in primary immunodeficiency disorders studied in 128 pediatric patients in Kuwait; skin infections were the most prevalent findings, seen in 39 patients (30%), followed by dermatitis in 24 (19%).[4] Skin infections were significantly more prevalent in those with congenital defects in phagocyte number, function, or both, as well as in those with well-defined immunodeficiencies. Dermatitis was evident in all patients with hyper–immunoglobulin (Ig) E syndrome and Wiskott-Aldrich syndrome.[4] Erythroderma of infancy with diffuse alopecia was seen exclusively in patients with SCID disorders, and telangiectasia in patients with ataxia telangiectasia; and partial albinism with silvery gray hair was associated with Chediak-Higashi syndrome. With the advances in BMT and gene therapy, patients now have a better likelihood of developing a functional immune system in a previously lethal genetic disease. However, once an infant develops serious infections, intervention is rarely successful.

Massive bone defects (>8 cm) will not unite without an additional intervention. They require a predictable, durable, and efficient method to regrow bone. The Ilizarov method of tension stress, or distraction osteogenesis, first involves a low-energy osteotomy1 - 5. The bone segments are then pulled apart, most often using an external device at a specific rate and rhythm (distraction phase), after which the newly formed bone (the regenerate) requires time for consolidation. The consolidation phase is variable and usually requires a substantially greater amount of time before the external device can be removed. Our technique of tibial bone transport over an intramedullary nail using cable and pulleys combines internal and external fixation, allowing the external fixator to be removed at the end of the distraction phase. This increases the efficiency of limb reconstruction and decreases the external-fixator-associated complications.