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Lipid-Lowering Agents HMG-CoA reductase inhibitors (statins) These agents inhibit the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase. Note the following: Low-density lipoprotein (LDL) reduction of 25%-60% Examples include Atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin Contraindications include hypersensitivity, active liver disease, pregnancy, lactation, coadministration with strong CYP3A4 inhibitors (selected statins) Vitamin B3 Vitamin B3 inhibits very-low-density lipoprotein (VLDL) synthesis. Note the following: LDL reduction of 10% High-density lipoprotein (HDL) increase of 20% Example includes Niacin (nicotinic acid) Contraindications include hypersensitivity, liver disease, active peptic ulcer, severe hypotension, arterial bleeding Fibrates Fibrates enhance lipoprotein lipase, resulting in increased VLDL catabolism, fatty acid oxidation, and triglycerides elimination. They decrease hepatic extraction of free fatty acids. Note the following: LDL reduction of 15% Triglyceride reduction of 35% Examples include Gemfibrozil, fenofibrate, fenofibrate (micronized), fenofibric acid Contraindications include active liver disease, renal disease, primary biliary cirrhosis, gallbladder disease 2-Azetidiones These agents inhibit sterol transporter at brush border and, consequently, intestinal absorption of cholesterol. LDL reduction of 15% Example includes Ezetimibe Contraindications include hypersensitivity, coadministration with statins (if active liver disease) Bile acid sequestrants These agents lower cholesterol and LDL via bile duct sequestration. Note the following: LDL reduction of 15% Examples include Cholestyramine, colesevelam, colestipol Contraindications include biliary/bowel obstruction, serum triglycerides >300-500 mg/dL, history of hypertriglyceridemia-induced pancreatitis

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Simple microinstruments and a medical school laboratory microscope were used for anastomosis training. Chicken blood vessels were used as a material for this study. A long segment of blood vessel from the proximal brachial artery to the distal radial artery was used for training. End-to-side anastomosis was practiced first, and the training continued with end-to-end anastomosis of the appropriate segments.

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Yannas had been studying collagen, a protein found in human skin. Teaming up during the 1970s, the two made a polymer (a chemical compound made of multiple repeating units). Using collagen fibers and a long sugar molecule, they formed a porous (full of small holes) material resembling skin.

How to Improve Sexual Health or Stamina part 4 All Solution of Male Disorder Male Infertility Diagnostic and Treatment Re-Slim Care Latest Technology in Pakistan Dr. Aslam Naveed is a well known sexologist in Pakistan. He has treated more than 1 Lac patients since last 30 years of clinical Practice in sexology, he knows how to help the people facing sexual disorders. Contact: 02134965050, 03432821919 www.sexologistpakistan.com https://www.facebook.com/menssexcareclinic/ https://youtu.be/_fRbtwWtLoE Part 1 https://youtu.be/S17bCnwCLuI Part 2 https://youtu.be/CPAXxkdz7mM Part 3 https://youtu.be/YlsdBZJ4prg Part 4 https://youtu.be/fylxbK4azvs Part 5 https://youtu.be/Zb8TcdgJ7Io Part 6 https://youtu.be/0wbDDNAwsmo Part 7 https://youtu.be/gHDmwfsMgTw Part 8 https://youtu.be/IasXoRKUlV4 Part 9 ADDRESS: Men’s Care Modern Hospital, Opposite, Safari Park, University Road, Karachi, Pakistan.

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An estimated 900,000 knee replacements are performed in the U.S. every year, but experts say about 15% of patients aren’t totally pleased with the outcome. An advancement in technology is focused on improving those outcomes.

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Interested in other medical videos? Click the link below to watch a surgery animation!
https://www.youtube.com/watch?v=Cc6-Y_CIHx4&t=53s&ab_channel=CourtroomAnimation

Or, if you want to watch a video about a diskectomy, a common but major surgery, watch this video:
https://www.youtube.com/watch?v=PVoOVUPhdaM&t=8s&ab_channel=CourtroomAnimation

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A 30 YEAR WOMEN WITH INTRACTABLE BILIARY COLIC

CASE REPORT: This 30 year women developed severe pain right upper quadrant for last 10 days. She sought many consultations and was given intravenous analgesics both (nonnarcortic and narcotic). Pain did not subside and she sought my consultation. Examination revealed her to be in agony with severe upper abdominal pain. General physical examination was otherwise unremarkable. Abdominal examination revealed mild tenderness in right hypochondrium with doubtful Murphy's sign. Urgent abdominal ultrasound showed a linear structure in bile ducts making slow writhing movements. The structure had an anechoic tube (alimentary canal) inside suggestive of a large Ascarid. Urgent ERCP was performed and bile duct and pancreatic duct cannulated selectively. Pancreatic duct was normal. Bile ducts contained a long linear filling defect extending from lower end of common bile duct to right intrahepatic duct (see image gallery for ERCP plate). A basket was introduced in the duct (see video clip) and the linear structure was engaged with soft closure and extracted out of the bile duct. Accompanying the basket was a 25 cm thick highly motile Ascarid. To recover the worm, endoscope was withdrawn along with the basket and the friendly catch. While the endoscope was being withdrawn and the basket was in the duodenum with the worm out of bile duct, patient indicated of relief of abdominal pain. A relook cholangiogram showed no more structures in the duct. She was given antihelmintic therapy and passed hundreds of worms with the feces. The worms recovered form stools were both male and female population and varied in length and size. However the lone worm recovered form bile ducts was the longest and the thickest male worm. The phenomenal behavior of this ubiquitous infection remains unexplained.

Watch that Above Knee Leg Amputation Surgery