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Lipid Lowering Agents
Lipid Lowering Agents samer kareem 2,883 Views • 3 years ago

Lipid-Lowering Agents HMG-CoA reductase inhibitors (statins) These agents inhibit the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase. Note the following: Low-density lipoprotein (LDL) reduction of 25%-60% Examples include Atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin Contraindications include hypersensitivity, active liver disease, pregnancy, lactation, coadministration with strong CYP3A4 inhibitors (selected statins) Vitamin B3 Vitamin B3 inhibits very-low-density lipoprotein (VLDL) synthesis. Note the following: LDL reduction of 10% High-density lipoprotein (HDL) increase of 20% Example includes Niacin (nicotinic acid) Contraindications include hypersensitivity, liver disease, active peptic ulcer, severe hypotension, arterial bleeding Fibrates Fibrates enhance lipoprotein lipase, resulting in increased VLDL catabolism, fatty acid oxidation, and triglycerides elimination. They decrease hepatic extraction of free fatty acids. Note the following: LDL reduction of 15% Triglyceride reduction of 35% Examples include Gemfibrozil, fenofibrate, fenofibrate (micronized), fenofibric acid Contraindications include active liver disease, renal disease, primary biliary cirrhosis, gallbladder disease 2-Azetidiones These agents inhibit sterol transporter at brush border and, consequently, intestinal absorption of cholesterol. LDL reduction of 15% Example includes Ezetimibe Contraindications include hypersensitivity, coadministration with statins (if active liver disease) Bile acid sequestrants These agents lower cholesterol and LDL via bile duct sequestration. Note the following: LDL reduction of 15% Examples include Cholestyramine, colesevelam, colestipol Contraindications include biliary/bowel obstruction, serum triglycerides >300-500 mg/dL, history of hypertriglyceridemia-induced pancreatitis

Pediatric ERCP
Pediatric ERCP samer kareem 1,988 Views • 3 years ago

Experience with endoscopic retrograde cholangiopancreatography (ERCP) in children has been limited due to multiple factors, including the relatively low incidence of diseases requiring ERCP in this age group, the impression that the procedure is technically difficult in children, and because the indications and safety of ERCP in children have not been well defined. As a result, patients are generally referred to a tertiary care facility or to adult endoscopists who perform a high volume of procedures.

Osteoporosis: Causes and treatment
Osteoporosis: Causes and treatment samer kareem 3,847 Views • 3 years ago

The discussion begins with a basic explanation of Bone biology taking into consideration the osteoblast and osteoclast balance. Concepts of RANK, RANK ligand and Osteoprotegerin are included. Risk factors for Osteoporosis such as Age, alcohol, smoking, sedentary lifestyle are also discussed.

Reduction of Inferior Shoulder Dislocation
Reduction of Inferior Shoulder Dislocation samer kareem 15,396 Views • 3 years ago

A technique for reducing an inferior shoulder dislocation. watch to learn more

Diabetic Ketoacidosis (DKA) 1
Diabetic Ketoacidosis (DKA) 1 samer kareem 2,151 Views • 3 years ago

This is video 1 of 2 on diabetic ketoacidosis (pathophysiology and signs of diabetic ketoacidosis / DKA):

Hemophagocytic Lymphohistiocytosis
Hemophagocytic Lymphohistiocytosis samer kareem 1,758 Views • 3 years ago

Hemophagocytic lymphohistiocytosis is a rare but life threatening condition characterised by activation of macrophages which result in phagocytosis of RBCs and cytokine mediated tissue damage. This presentation aims to discuss the genetic basis, clinical features, diagnostic criteria and management options in this serious condition. The management options in HLH include Etoposide, Dexamethasone, Cyclosorine, Tacrolimus, Alemtuzumab and stem cell transplant.

Orbit examination (basic)
Orbit examination (basic) Mohamed Ibrahim 36,688 Views • 3 years ago

Eye tests are important for the detection of many common eye infections and diseases. Eyes are also an important indicator to detect chronic systemic diseases like Hypertension and Diabetes.  Must after maxillofacial trauma to rule out any near and late complications emerging for the eyes. 2. There are two perspectives for examining the eyes : 1. Ophthalmic Perspective – because eyes are prone to many infections, diseases and conditions. 2. Maxillofacial Perspective – because the eyes and the orbit forms an integral component of facial and mid-facial fractures and trauma.

What is a Makoplasty Partial Knee Replacement?
What is a Makoplasty Partial Knee Replacement? samer kareem 1,823 Views • 3 years ago

The MAKOplasty® procedure is an FDA-cleared treatment option for patients who suffer from osteoarthritis damage in the medial (inner) portion of the knee. ... Only the diseased portion of your knee is removed, leaving the healthy bone and tissue surrounding it untouched.

Breast Enlargement Animation
Breast Enlargement Animation Landging 4,954 Views • 3 years ago

http://www.landging.com/breast-enlargement-animation.html
Breast enlargement product animation designed for TV shopping.

Ischemic Colitis
Ischemic Colitis samer kareem 1,631 Views • 3 years ago

Ischemic colitis occurs when blood flow to part of the large intestine (colon) is reduced, usually due to narrowed or blocked blood vessels (arteries). The diminished blood flow doesn't provide enough oxygen for the cells in your digestive system. Ischemic colitis can cause pain and may damage your colon. Any part of the colon can be affected, but ischemic colitis usually causes pain on the left side of the belly area (abdomen). The condition can be misdiagnosed because it can easily be confused with other digestive problems. Ischemic colitis may heal on its own. But you may need medication to treat ischemic colitis or prevent infection, or you may need surgery if your colon has been damaged. Symptoms ShareTweet Oct. 13, 2015 References Products and Services Newsletter: Mayo Clinic Health Letter See also Abdominal pain Colonoscopy Color Blue Detects Colon Cancer CT scan CT scans: Are they safe? Diarrhea Ultrasound Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship PolicyOpportunitiesAd Choices Mayo Clinic Store Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. NEW! – The Mayo Clinic Diet, Second Edition Treatment Strategies for Arthritis Mayo Clinic on Better Hearing and Balance Keeping your bones healthy and strong The Mayo Clinic Diet Online Ads by Swoop Psoriasis Treatment www.informationaboutpsoriasis.com Explore a Treatment Option for Moderate to Severe Plaque Psoriasis Immune Biomarker PD-L1 - Discover the Science iobiomarkers.bmsinformation.com Understanding Assay Results for PD-L1 is Crucial for Treatment Decisions. Biomarker PD-L1 Information - Easy to Download Resources iobiomarkers.bmsinformation.com Explore the Role of PD-L1 in Immuno-Oncology & the Evolving Biomarker Landscape.

Dr Omid Liaghat Replantation Case 02
Dr Omid Liaghat Replantation Case 02 Dr Omid Liaghat 1,244 Views • 3 years ago

26 years old man lost his right hand thumb and index fingers with an industrial machine.the thumb amputated part was not found. the thumb is much more important of any other finger in the hand and should be reconstructed by any means. so the index amputated part was filleted and replanted over the thumb stump. the video is taken 1 year after replantation. You can see another videos in my site: https://drliaghatclinic.com, https://instagram.com/liaghatclinic, https://t.me/liaghatclinic

glomus tumor
glomus tumor samer kareem 2,271 Views • 3 years ago

Glomus tumors are rare soft tissue neoplasms that typically present in adults (ages 20-40 years) as small, blue-red papules or nodules of the distal extremities, with most cases involving subungual sites. These tumors are typically painful, often causing paroxysmal pain in response to temperature changes or pressure. Glomus tumors are thought to arise from the glomus body, a thermoregulatory shunt concentrated in the fingers and toes. Most lesions are solitary and localized to cutaneous sites; however, generalized glomuvenous malformations, or multiple glomangiomas, have also been described, and may have extracutaneous involvement.

Meningitis Examination
Meningitis Examination samer kareem 2,320 Views • 3 years ago

Myopia Animation
Myopia Animation DrHouse 18,055 Views • 3 years ago

This animated video reviews myopia, which is the medical term for nearsightedness.

Anatomy of The Upper Limb Joints
Anatomy of The Upper Limb Joints Anatomy_Videos 8,664 Views • 3 years ago

Anatomy of The Upper Limb Joints

Croup Case
Croup Case samer kareem 1,583 Views • 3 years ago

Croup is a common respiratory camera.gif problem in young children. It tends to occur in the fall and winter. Its main symptom is a harsh, barking cough. Croup causes swelling and narrowing in the voice box, windpipe, and breathing tubes that lead to the lungs. This can make it hard for your child to breathe. An attack of croup can be scary, but it is rarely serious. Children usually get better in several days with rest and care at home.

Liddle's Syndrome
Liddle's Syndrome samer kareem 1,910 Views • 3 years ago

Liddle syndrome is an inherited form of high blood pressure (hypertension). This condition is characterized by severe hypertension that begins unusually early in life, often in childhood, although some affected individuals are not diagnosed until adulthood. Some people with Liddle syndrome have no additional signs or symptoms, especially in childhood. Over time, however, untreated hypertension can lead to heart disease or stroke, which may be fatal.

Hemorrhoids Piles Surgery Animation
Hemorrhoids Piles Surgery Animation Scott 15,466 Views • 3 years ago

Stapling is used to treat prolapsed hemorrhoids. A surgical staple fixes the prolapsed hemorrhoid back into place inside your rectum and cuts off the blood supply so that the tissue will shrink and be reabsorbed. Stapling recovery takes less time and is less painful than recovery from a hemorrhoidectomy.

Pediatric Laparoscopic Cholecystectomy
Pediatric Laparoscopic Cholecystectomy DrPhil 16,159 Views • 3 years ago

it's a 8 years old boy with previous medical history of Sickle cell disease presented with gall stone and repeat abdominal pain. A laparoscopic cholecystectomy is performed. The cystic duct is controlled with 2 stiches of absorbable suture. The cystic artery is simply cauterized with the hook cauter...y. the specimen is removed through the umbilical port using an 10mm endobag.

Open Heart Surgery Repair
Open Heart Surgery Repair samer kareem 2,876 Views • 3 years ago

Heart Surgery | 8 Years Old Girl Open Heart Surgery Repair

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