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Osgood-Schlatter disease can cause a painful lump below the kneecap in children and adolescents experiencing growth spurts during puberty. Osgood-Schlatter disease occurs most often in children who participate in sports that involve running, jumping and swift changes of direction — such as soccer, basketball, figure skating and ballet. While Osgood-Schlatter disease is more common in boys, the gender gap is narrowing as more girls become involved with sports. Age ranges differ by sex because girls experience puberty earlier than do boys. Osgood-Schlatter disease typically occurs in boys ages 13 to 14 and girls ages 11 to 12. The condition usually resolves on its own, once the child's bones stop growing.
Osteomyelitis is an infection in a bone. Infections can reach a bone by traveling through the bloodstream or spreading from nearby tissue. Infections can also begin in the bone itself if an injury exposes the bone to germs. In children, osteomyelitis most commonly affects the long bones of the legs and upper arms. Adults are more likely to develop osteomyelitis in the bones that make up the spine (vertebrae). People who have diabetes may develop osteomyelitis in their feet if they have foot ulcers. Once considered an incurable condition, osteomyelitis can be successfully treated today. Most people require surgery to remove parts of the bone that have died — followed by strong antibiotics, often delivered intravenously, typically for at least four to six weeks.
Cisplatin is in a class of drugs known as platinum-containing compounds used to treat various types of cancers including metastatic testicular and ovarian tumors. The molecule was first discovered in 1845, but did not receive FDA approval until 1978. Today it is known as the "penicillin of cancer drugs," because it is so effective for many different cancers. There are three key players involved in Cisplatin's mechanism: (1) Cisplatin, (2) DNA (3) and an HMG Protein. Most Cisplatin enters the body through active transport, but some molecules are passively defused through the cell membrane. Once in the nucleus, Cisplatin can form an adduct with two consecutive guanine bases within a strand of DNA. The molecule loses its chlorine atoms in exchange for the nitrogen atoms of the target guanines. Cisplatin can bond more tightly with nitrogen because nitrogen balances the platinum charge more effectively than chlorine. It is this adduct-induced DNA bend that allows binding of proteins which contain the high mobility group, HMG domain. Once the protein is bound to the DNA, it inserts a wedge-like phenyl group of phenylalanine 37 into the widened minor groove created by the bend. The tightly bound HMG protein causes destacking of the nucleotide bases, resulting in the DNA helix becoming kinked. In this way, Cisplatin can be thought of as a monkey wrench in the DNA repair system. With the HMG protein bound to the DNA, the modified strand is not repaired properly and so the cell dies. The success of Cisplatin depends on its ratio of efficacy between cancerous and healthy cells.
Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but they can also damage other parts of the body. TB spreads through the air when a person with TB of the lungs or throat coughs, sneezes, or talks. If you have been exposed, you should go to your doctor for tests. You are more likely to get TB if you have a weak immune system. Symptoms of TB in the lungs may include A bad cough that lasts 3 weeks or longer Weight loss Loss of appetite Coughing up blood or mucus Weakness or fatigue Fever Night sweats
A unique look into laboratory techniques for egg freezing, also known as oocyte cyropreservation. Take an exclusive look inside one of the most advanced, state-of-the-art in vitro fertilization (IVF) laboratories to see how RMA of New York performs egg freezing procedures using strict identification standards. Medical and laboratory video footage documents egg retrieval, egg identification from follicular fluid, preparation for preservation, and the cyropreservation and storage process for egg freezing. RMA of New York is proud to partner with Extend Fertility ™ to offer egg freezing services. To learn more, please visit Reproductive Medicine Associates of New York www.rmany.com/fertility-hope Or Extend Fertility http://www.extendfertility.com 635 Madison Avenue, 10th floor New York, New York 10022 Telephone: (212) 756-5777 Facsimile: (212) 756-5770 15 North Broadway, Garden Level - Suite G White Plains, New York 10601 Telephone: (914) 997-6200 Facsimile: (914) 997-8111 Reproductive Medicine Associates of New York, Long Island 400 Garden City Plaza, Suite 107 Garden City, NY 11530 Telephone: (516) 746-3633 Facsimile: (516) 746-3622 Reproductive Medicine Associates International Mexico, S.C. Prolongacion Paseo de la Reforma 1232, Oficina 1213 Colonia Lomas de Bezares Delegacion Miguel Hidalgo Mexico, Distrito Federal 11910 Telephone: 011-52-55-2167-2515 Fax: 011-52-55-2167-6434
Bone tumors develop when cells in the bone divide without control, forming a mass of tissue. Most bone tumors are benign, which means they are not cancer and cannot spread. However, they may still weaken bone and lead to fractures or cause other problems. Bone cancer destroys normal bone tissue and may spread to other parts of the body (called metastasis). Benign Bone Tumors Benign tumors are more common than malignant tumors of the bones. These are a few common types of benign bone tumors: Osteochondroma is the most common benign bone tumor. It is more common in people under age 20. Giant cell tumor is a benign tumor, typically affecting the leg (malignant types of this tumor are uncommon). Osteoid osteoma is a bone tumor, often occurring in long bones, that occurs commonly in the early 20s. Osteoblastoma is a single tumor that occurs in the spine and long bones, mostly in young adults. Enchondroma usually appears in bones of the hand and feet. It often has no symptoms. It is the most common type of hand tumor.
Robotic surgery was developed to facilitate endoscopic surgery and overcome its disadvantage. Thus, we performed robotic Total Mesorectal Excison (TME) in patient with rectal cancer by using the Intuitive Surgical® da Vinci surgicalTM system (Intuitive Surgical®, Sunnyvale, CA). To our knowledge, ...this is the first robotic low anterior resection base on standard TME principle with pelvic autonomic preservation. In conclusion, Robotic system is the best operative instrument for performing the standard TME procedure in rectal cancer patients.
ICDs are useful in preventing sudden death in patients with known, sustained ventricular tachycardia or fibrillation. Studies have shown ICDs to have a role in preventing cardiac arrest in high-risk patients who haven't had, but are at risk for, life-threatening ventricular arrhythmias. View an animation of an ICD. Newer-generation ICDs may have a dual function which includes the ability to serve as a pacemaker. The pacemaker feature would stimulate the heart to beat if the heart rate is detected to be too slow. What is an Implantable Cardioverter Defibrillator (ICD)? An ICD is a battery-powered device placed under the skin that keeps track of your heart rate. Thin wires connect the ICD to your heart. If an abnormal heart rhythm is detected the device will deliver an electric shock to restore a normal heartbeat if your heart is beating chaotically and much too fast. ICDs have been very useful in preventing sudden death in patients with known, sustained ventricular tachycardia or fibrillation. Studies have shown that they may have a role in preventing cardiac arrest in high-risk patients who haven't had, but are at risk for, life-threatening ventricular arrhythmias.
Acclaimed sexologist Hanny Lightfoot-Klein, author of several highly illuminating books on genital mutilation, discusses compromises in orgasm after male circumcision. Also commenting is cultural anthropologist James De Meo.From the groundbreaking documentary film, "Whose Body, Whose Rights?"
More than 1 million Americans suffer a heart attack every year. Traditional symptoms—chest pain or pressure, cold sweat, extreme weakness—are well known. But there are more subtle signs you’re having or are about to have a heart attack that can be easy to miss. If you experience any of the following symptoms, see a doctor. Noticing heart attack signs early and getting prompt treatment can save your life.
Majority of patients these days prefer PCNL ( Minimal Invasive Telescopic removal of kidney stones broken with lithoclast, removed through a button hole incision ). This patient with a big stone in the pelvis of the kidney wanted it open only so I did an open pyelolithotomy for this patient after a long time as I use to do it in routine in the past. Except for the long incision and scar as compared to PCNL the recovery time was the same and patient went home third day happily walking and eating.