Severe combined immunodeficiency (SCID) is a life-threatening syndrome of recurrent infections, diarrhea, dermatitis, and failure to thrive. It is the prototype of the primary immunodeficiency diseases and is caused by numerous molecular defects that lead to severe compromise in the number and function of T cells, B cells, and occasionally natural killer (NK) cells. Clinically, most patients present before age 3 months. Without intervention, SCID usually results in severe infection and death in children by age 2 years. A committee of experts, initially sponsored by the World Health Organization (WHO), meets every 2 years with the goal to classify the group of primary immunodeficiency diseases according to current understanding of the pathways that become defective in the immune system.[1] Eight classification groups have been determined, with SCID being one of the best studied. Over the past few decades, the diverse molecular genetic causes of SCID have been identified with progress from studies of the immune system.[2] SCID is considered a pediatric emergency because survival depends on expeditious stem cell reconstitution, usually by bone marrow transplantation (BMT). Appropriate diagnosis is essential because instituting proper treatment is lifesaving. Despite the heterogeneity in the pathogenesis of immune defects, common cutaneous manifestations and typical infections can provide clinical clues in diagnosing this pediatric emergency.[3] Skin manifestations were prevalent in primary immunodeficiency disorders studied in 128 pediatric patients in Kuwait; skin infections were the most prevalent findings, seen in 39 patients (30%), followed by dermatitis in 24 (19%).[4] Skin infections were significantly more prevalent in those with congenital defects in phagocyte number, function, or both, as well as in those with well-defined immunodeficiencies. Dermatitis was evident in all patients with hyper–immunoglobulin (Ig) E syndrome and Wiskott-Aldrich syndrome.[4] Erythroderma of infancy with diffuse alopecia was seen exclusively in patients with SCID disorders, and telangiectasia in patients with ataxia telangiectasia; and partial albinism with silvery gray hair was associated with Chediak-Higashi syndrome. With the advances in BMT and gene therapy, patients now have a better likelihood of developing a functional immune system in a previously lethal genetic disease. However, once an infant develops serious infections, intervention is rarely successful.

This information is collected from Oncolex. For more on colon and rectum (

Nose cautery can help prevent nosebleeds. The doctor uses a chemical swab or an electric current to cauterize the inside of the nose. This seals the blood vessels and builds scar tissue to help prevent more bleeding. For this procedure, your doctor made the inside of your nose numb.

Watch that Ectopic Baby Medical Abortion Surgery

Liver Transplant Surgery Explained

Deep Vein Thrombosis Treatment With Trellis Procedure

Patent ductus arteriosus (PDA), in which there is a persistent communication between the descending thoracic aorta and the pulmonary artery that results from failure of normal physiologic closure of the fetal ductus (see image below), is one of the more common congenital heart defects.

This animated video reviews myopia, which is the medical term for nearsightedness.

Another video of Dr.Vijay C. Bose from Apollo Speciality Hospital chennai perform Birmingham Hip Resurfacing Surgery procedure for a case of Avascular necrosis.The NCP ( Neck Capsule Preserving) approach is being used. Total hip replacement, hip resurfacing simply shaves and caps a few centimeters of bone within the joint. The bone-conserving approach of the Birmingham Hip Resurfacing System.

Insulin is a hormone made naturally in the pancreas that helps move sugar into the cells of your body. Your cells use the sugar as fuel to make energy. Without enough insulin, sugar stays in your bloodstream, raising your blood sugar. High blood sugar, or hyperglycemia, can lead to the signs and symptoms of diabetes:

Angina is a term used for chest pain caused by reduced blood flow to the heart muscle. Angina (an-JIE-nuh or AN-juh-nuh) is a symptom of coronary artery disease. Angina is typically described as squeezing, pressure, heaviness, tightness or pain in your chest. Angina, also called angina pectoris, can be a recurring problem or a sudden, acute health concern. Angina is relatively common but can be hard to distinguish from other types of chest pain, such as the pain or discomfort of indigestion. If you have unexplained chest pain, seek medical attention right away.

Watch that video of The Worst Fingers Infections Ever

Liposuction is a surgical procedure that is done to remove fat deposits from underneath the skin. Common areas that are treated: the abdomen, buttocks, thighs, upper arms, chest and neck. (use medical graphic of body with labeled parts) The procedure is usually done as an outpatient under some combination of local anesthesia and/or sedation:. This means you are awake but relaxed and pain free. Depending on the number of areas to be treated and the specific technique selected, it may take from one to several hours. A small incision (cut) is made through the skin near the area of the fat deposit. Multiple incisions may be needed if a wide area or multiple areas are being done. A long hollow tube called a cannula will be inserted through this incision. Prior to inserting the cannula, the doctor may inject a solution of salt water that contains an anesthetic (numbing) medication and another medication to decrease bleeding. The cannula is then inserted and moved under the skin in a way to loosen the fat deposits so they may be suctioned out. Because a significant amount of body fluid is removed with the fat, an intravenous (through the veins) fluid line will be kept going during the procedure.

A recent technique called “ultrasound-assisted lipoplasty” uses a special cannula that liquefies the fat cells with ultrasonic energy. You should ask your doctor which technique he/she will use and how it will affect the type of anesthesia you will need and the length of the procedure.

Why is this procedure performed?
Liposuction is done to restore a more normal contour to the body. The procedure is sometimes described as body sculpting. It should be limited to fat deposits that are not responsive to diet and exercise. It is suggested that you should be within 20of your ideal body weight at the time of surgery. If you are planning to lose weight you should delay this procedure. This is not obesity surgery. The maximum amount of fat that can be removed is usually less than 10 pounds. The best results are achieved in people who still have firm and elastic skin. Although rare, there are risks and complications that can occur with liposuction. You should be aware that all the complications are increased if you are a smoker. You will need to quit smoking or at least avoid smoking for a month before and after surgery. If you have had prior surgeries near any of the areas to be treated, this may increase the risk of complications and you should discuss this with your doctor. Any history of heart disease, diabetes, bleeding problems or blood clots in your legs may make you more prone to post-operative problems and you should discuss these with your doctor. Finally, as with any cosmetic procedure it is important to have realistic expectations. The goals, limitations, and expectations of the procedure should be discussed openly and in detail with your doctor. Most insurance companies do not cover cosmetic surgery.

What should I expect during the post-operative period?
After surgery you should be able to go home but you will need someone to drive you. In the first few days after surgery it is common for the incisions to drain fluid and you will have to change dressings frequently. Fresh blood is not usual and if you have any bleeding you should call your doctor immediately. In some cases a small tube may have been placed through the skin to allow drainage. You will be limited to sponge baths until the drains and dressings are removed. After that you may take showers but no baths for 2 weeks. You may experience pain, burning, and numbness for a few days. Take pain medicine as prescribed by your doctor. You may notice a certain amount of bruising and swelling. The bruising will disappear gradually over 1 to 2 weeks. Some swelling may last for up to 6 months. If you have skin sutures they will be removed in 7 to 10 days. You should be able to be up and moving around the house the day after surgery but avoid any strenuous activity for about 1

Rehabilitation time for a meniscus repair is about 3 months. A meniscectomy requires less time for healing — approximately 3 to 4 weeks. Meniscus tears are extremely common knee injuries. With proper diagnosis, treatment, and rehabilitation, patients often return to their pre-injury abilities.

TRANSUMBILICAL SINGLE SITE LAP CHOLYCYSTECTOMY

Inguinal hernia repair without mesh, Desarda Repair, no recurrence, pain, no mesh hernia surgery, hernia operation, no mesh, without mesh, hernia operation, hernia surgery, new method.http://www.desarda.com

The hip is a "ball-and-socket" joint. In a normal hip, the ball at the upper end of the thighbone (femur) fits firmly into the socket, which is part of the large pelvis bone. In babies and children with developmental dysplasia (dislocation) of the hip (DDH), the hip joint has not formed normally.

HD Hip Replacement Surgery

HD Cataract Surgery Video

The journey of egg and sperm. There are a lot of casualties (deaths) among the sperm as they swim toward the egg. First, many get lost in the maze of a woman's uterus where they also have to contend with acidic vaginal secretions.