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TPE removes large-molecular-weight substances such as harmful antibodies from the plasma. It is usually carried out using an automated blood cell separator to ensure fluid balance and maintain a normal plasma volume. This may require the insertion of a femoral or jugular line to allow adequate blood flow. Typically, 30–40 mL/kg of plasma (1–1.5 plasma volumes) are removed at each procedure and replaced with isotonic 4.5 or 5.0% human albumin solution (some services substitute 25–50% of replacement volume with 0.9% saline). Exchange with fresh frozen plasma (FFP) is reserved for the replacement of ADAMTS13 in thrombotic thrombocytopenic purpura (see below) or to replace clotting factors. A one plasma volume exchange removes about 66% of an intravascular constituent and a two plasma volume exchange approximately 85%. TPE is normally combined with disease modifying treatment, such as immunosuppressive drugs, for the underlying condition.
Low potassium (hypokalemia) refers to a lower than normal potassium level in your bloodstream. Potassium is a chemical (electrolyte) that is critical to the proper functioning of nerve and muscles cells, particularly heart muscle cells. Normally, your blood potassium level is 3.6 to 5.2 millimoles per liter (mmol/L). A very low potassium level (less than 2.5 mmol/L) can be life-threatening and requires urgent medical attention.
Antiarrhythmics are drugs that are used to treat abnormal heart rhythms resulting from irregular electrical activity of the heart. There are many different types of antiarrhythmic drugs. Examples include: Amiodarone (Cordarone) Flecainide (Tambocor) Procainamide (Procanbid) Sotalol (Betapace) In addition, there are other types of heart drugs that can be used to treat arrhythmias, including: Beta-blockers such as metoprolol or Toprol XL, which reduce the heart's workload and heart rate. Calcium channel blockers such as verapamil or Calan, which also reduces the heart rate.
This video shows Prof Dan Reinstein, MD MA(Cantab) FRCSC DABO FRCOphth FEBO performing a ReLEx SMILE keyhole LASIK procedure using the latest surgical instrument that he helped to develop (Malosa MMSU1297 - Reinstein Lenticule Separator: http://www.malosa.com/en/reinstein-le...). This instrument enables the procedure to be performed with one instrument, through one 2mm incision, using only one sweep per plane, and taking about 30 seconds to separate and withdraw the lenticule, improving day 1 uncorrected vision over other lenticule extraction techniques that require more corneal manipulation.
Rheumatoid arthritis is a chronic inflammatory disorder that can affect more than just your joints. In some people, the condition also can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels. An autoimmune disorder, rheumatoid arthritis occurs when your immune system mistakenly attacks your own body's tissues. Unlike the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the lining of your joints, causing a painful swelling that can eventually result in bone erosion and joint deformity. The inflammation associated with rheumatoid arthritis is what can damage other parts of the body as well. While new types of medications have improved treatment options dramatically, severe rheumatoid arthritis can still cause physical disabilities.
The shoulder and arm receives its nerve supply through the brachial plexus. The brachial plexus is a complex network of nerves which come out of the neck, passes down to the front of the shoulder and then splits into many separate nerves to travel to different muscles and parts of the skin. Normally an arm movement is produced by initially thinking of the movement, then a message passes from the brain, down through the spinal cord to the appropriate nerve. Then the instruction to move is conveyed along the nerve to the specific arm muscle which then contracts and moves the arm.
Dr. Ebraheim’s educational animated video describing the anatomy and associated injuries of the knee joint.
Disrupted quadriceps
•Patient is unable to actively extend the knee.
The most common cause of ACL ruptures:
•Traumatic force being applied during twisting motion.
•Side stepping or landing from a jump.
Patient complains of:
•Immediate pain
•Knee giving way
•Swelling
Aspiration of the knee
•If aspiration of the knee joint shows evidence of blood within the joint there is 75-80% chance of ACL and meniscal injury.
Lachamn’s test- ACL knee exam
•Knee is flexed at 30 degrees.
•ACL tear of the knee is identified by pulling on the tibia and examining the frontward motion of the lower leg in comparison to the upper leg.
Radiological exam – ACL
•MRI of the knee joint shows bone lesions or bruising associated with tears of the ACL. Injury is found in the typical location; middle of the femoral condyle and posterior part of the tibia laterally.
Posterior cruciate ligament tear (PCL)
•Common cause of injury is a bent knee hitting a dashboard in a car accident.
Tibial Sag Test –PCL knee exam
Quadriceps active test-PCL knee exam
•The examiner stabilizes the leg of the patient and then the patient is asked to actively contract the quadriceps muscle.
•The tibia is seen actively reduced from the posterior subluxed position.
Lachman’s test-PCL knee exam
•Knee is bent 20-30 degrees.
•The posterior drawer test is carried out while the patient is in a supine position and the knee is flexed to 90 degrees.
•The amount of translation of the tibia relative to the femur is observed.
The dial test is performed while the patient is in the supine or prone position and both knees are in 90 and 30 degrees of flexion. More than 10 degrees of external rotation indicates significant injury.
Common meniscal tears
Symptoms include
•Knee pain
•Pain with straightening the knee
•Swelling
•Locking
•Weakness
HYSTERECTOMY RECOVERY: ALL PROCEDURES ARE NOT CREATED EQUAL Too often, women are only given the option of an open hysterectomy for conditions like large fibroids or an enlarged uterus. Surgical techniques have evolved in the last decade, but across the United States, the number of women still having open hysterectomy procedures is unnecessarily staggering. Robotic procedures are becoming more common as hospitals invest nearly $2 million in the machine. While the robot does allow surgeons who are not necessarily trained in laparoscopic procedures to perform a more minimally invasive surgery, tools cannot replace skill. There is no added benefit to the patient and the surgery can cost on average up to $2,000 more than other laparoscopic options, and in some cases much higher.
Repairing a myelomeningocele in utero, rather than after birth, reduces the risk for fetal or neonatal death and the need for shunting by age 1 and substantially improves neurologic and motor outcomes. However, it is not without maternal and fetal risks. These are the findings, in a nutshell, of the long-awaited Management of Myelomeningocele Study (MOMS), which were published online February 9 in The New England Journal of Medicine.
Beating heart or "off pump" coronary artery surgery is the latest revolution in the management coronary disease. It is being embraced world-wide by increasing numbers of surgeons. Many of the advantages are subtle but reduced mortality, stroke, and bleeding as well as earlier discharge are well-established benefits. A cardiac stabiliser is mandatory for this surgery, most are single use only and very expensive, this one is multiple use and is saving many healthcare dollars
A visual prosthesis, often referred to as a bionic eye, is an experimental visual device intended to restore functional vision in those suffering from partial or total blindness. In 1983 Joao Lobo Antunes, a Portuguese doctor, implanted a bionic eye in a person born blind.