Gastrointestinal GI Drug Delivery

Part 7: from Loyola Medical School, Chicago showing clinical examination of the neurological system.

This video shows the heart transplant surgery

What Causes Ulcers? No single cause has been found for ulcers. However, it is now clear that an ulcer is the end result of an imbalance between digestive fluids in the stomach and duodenum. Most ulcers are caused by an infection with a type of bacteria called Helicobacter pylori (H. pylori). Factors that can increase your risk for ulcers include: Use of painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, naproxen (Aleve, Anaprox, Naprosyn, and others), ibuprofen (Motrin, Advil, some types of Midol, and others), and many others available by prescription; even safety-coated aspirin and aspirin in powered form can frequently cause ulcers. Excess acid production from gastrinomas, tumors of the acid producing cells of the stomach that increases acid output (seen in Zollinger-Ellison syndrome) Excessive drinking of alcohol Smoking or chewing tobacco Serious illness Radiation treatment to the area What Are the Symptoms of an Ulcer? An ulcer may or may not have symptoms. When symptoms occur, they may include: A gnawing or burning pain in the middle or upper stomach between meals or at night Bloating Heartburn Nausea or vomiting In severe cases, symptoms can include: Dark or black stool (due to bleeding) Vomiting blood (that can look like "coffee-grounds") Weight loss Severe pain in the mid to upper abdomen

An intracranial hematoma occurs when a blood vessel ruptures within your brain or between your skull and your brain. The collection of blood (hematoma) compresses your brain tissue. An intracranial hematoma may occur because the fluid that surrounds your brain can't absorb the force of a sudden blow or a quick stop. Then your brain may slide forcefully against the inner wall of your skull and become bruised. Although some head injuries — such as one that causes only a brief lapse of consciousness (concussion) — can be minor, an intracranial hematoma is potentially life-threatening and often requires immediate treatment. An intracranial hematoma often, but not always, requires surgery to remove the blood.

Dr. David Rivadeneira from Stony Brook University in Stony Brook, NY will host a panel discussion on how to obtain improved outcomes during open surgery through the application of advanced techniques and technologies, including the new LigaSure Impact™ instrument. "It provides excellent and reliable hemostasis on major blood vessels, but the big advancement is that it is faster than traditional techniques and leaves no foreign material behind."

The program will begin with a brief introduction of the topic, followed by video presentation of two procedures, a right hemicolectomy and a sigmoid colectomy. Dr. Rivadeneira will discuss the techniques that he uses. "You'll be able to see the impact of applying multifunctional energy-based instruments to enable rapid and reliable dissection of the mesentery and ligation of colonic blood supply. This is particularly evident on tough diverticular cases, where it works very well with complicated tissue." Joining Dr. Rivadeneira, to review and discuss the cases, will be Dr. Sang Lee from Weill Cornell Medical College, NY.

This video, Rheumatoid arthritis is a chronic inflammatory disorder that can affect more than just your joints. In some people, the condition also can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels. An autoimmune disorder, rheumatoid arthritis occurs when your immune system mistakenly attacks your own body's tissues. Unlike the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the lining of your joints, causing a painful swelling that can eventually result in bone erosion and joint deformity. The inflammation associated with rheumatoid arthritis is what can damage other parts of the body as well. While new types of medications have improved treatment options dramatically, severe rheumatoid arthritis can still cause physical disabilities.

In this video I discuss sexual function for people with a spinal cord injury. The amount of feeling and function can vary drastically depending on the level and severity of the injury to the spinal cord.

Multicystic dysplastic kidney (MCDK) is a condition that results from the malformation of the kidney during fetal development. The kidney consists of irregular cysts of varying sizes. Multicystic dysplastic kidney is a common type of renal cystic disease, and it is a cause of an abdominal mass in infants.

Watch that video of Surgery to Remove Chainsaw Blade From Man's Neck

A video showing the phases of normal wound healing

While the incidence of most sports-related injuries has been holding steady for the past two decades, injuries to the anterior cruciate ligament (ACL) continue to increase significantly, particularly in female athletes. In fact, on many college teams, as many as 30 to 50 percent of young women have had an ACL injury during their high school careers in certain sports, such as basketball, soccer and gymnastics.
Watch pediatric orthopedic surgeons at Akron Children's Hospital perform arthroscopic surgery to replace a young athlete's ACL

Spinal stenosis can put pressure on the spinal cord and the nerves within the spine. It commonly occurs in the neck and lower back. The condition is often caused by age-related wear and tear. Symptoms, if they occur, include pain, numbness, muscle weakness, and impaired bladder or bowel control. Treatment includes medication, physical therapy, and possibly surgery

Papillary fibroelastoma is the third most common primary tumor of the heart and is most likely to involve the cardiac valves. Like myxomas, they arise from the endocardium in most patients and since these tumors are often incidental findings at echocardiography or autopsy, the true incidence is difficult to estimate. Most patients are older than 60 years, which also contrasts with myxomas. Papillary fibroelastomas can embolize, leading to severe neurological complications and therefore, surgical removal is advised, although there is controversy regarding small incidental lesions and the need for surgery.

Stay active and push your body to its limit – tips on how you can mend strained muscles and prevent injury.

Patients with candida endophthalmitis who have chorioretinitis with vitreal involvement should be treated with vitrectomy and systemic antifungal therapy with amphotericin B (Choice B) and/or fluconazole. An early vitrectomy improves the likelihood of a positive outcome, and intravitreal injection of amphotericin B may be of help. Prompt diagnosis and treatment of candida endophthalmitis is essential, as the condition can worsen quickly.

How a simple conversation about colon cancer screening can save your life.

Medications to treat high blood pressure Thiazide diuretics. ... Beta blockers. ... Angiotensin-converting enzyme (ACE) inhibitors. ... Angiotensin II receptor blockers (ARBs). ... Calcium channel blockers. ... Renin inhibitors

Central venous access is essential in providing quality medical care to many patients for whom intensive therapy is required. In many situations, a semipermanent tunneled central line is preferred (see Indications). An anterior approach to the internal jugular vein (IJV) is the best option in this situation because it offers the easiest route with a low risk of complications. In this procedure, a tunneled catheter is surgically inserted into a vein in the neck or chest and passed under the skin. Only the end of the catheter is brought through the skin; medicines and intravenous (IV) fluid can be administered through this catheter; other tasks, such as blood sampling, can also be performed. The fact that the catheter is passed under the skin helps secure the catheter, reduces the rate of infection, and permits free movement of the catheter port. The placement of a tunneled catheter should be carried out by practitioners with specific experience in the procedure.

Cholecystectomy means removal of the gallbladder. The most common reasons
your doctor might recommend a cholecystectomy are biliary colic, cholecystitis,
choledocolithiasis, or gallstone pancreatitis. Biliary colic, also known as symptomatic
cholelithiasis, is caused by gallstones, which are hardened deposits of bile. Gallstones are
common in the general population, and gallstones alone are not a reason for gallbladder
removal if they do not cause symptoms. However, sometimes gallstones can get caught at the
neck of the gallbladder, causing pain when the gallbladder contracts against them trying to
release its bile, especially after a fatty meal. With biliary colic, the pain typically resolves within
an hour or so. Occasionally, a stone or some other blockage may prevent the gallbladder from
emptying over a long period of time, causing an increase in pressure and trapped fluid within the
gallbladder. This can cause inflammation and infection of the gallbladder, which we call
cholecystitis. Choledocholithiasis is when there are one or more stones in the bile ducts, which
can cause back up of bile into the liver, and depending on the location of the stones, could
cause pancreatitis, which is inflammation of the pancreas. Other reasons for gallbladder
removal, though less common, are gallbladder polyps and cancer. All of these are reasons for
gallbladder removal.