1. What is hemodialysis?
2. Why do you do hemodialysis?
3. How does hemodialysis remove body waste?
4. What are the symptoms and side effects of hemodialysis?
5. How should I eat food when I do hemodialysis?
6. What are some precautions for patients during hemodialysis?


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Cisplatin is in a class of drugs known as platinum-containing compounds used to treat various types of cancers including metastatic testicular and ovarian tumors. The molecule was first discovered in 1845, but did not receive FDA approval until 1978. Today it is known as the "penicillin of cancer drugs," because it is so effective for many different cancers. There are three key players involved in Cisplatin's mechanism: (1) Cisplatin, (2) DNA (3) and an HMG Protein. Most Cisplatin enters the body through active transport, but some molecules are passively defused through the cell membrane. Once in the nucleus, Cisplatin can form an adduct with two consecutive guanine bases within a strand of DNA. The molecule loses its chlorine atoms in exchange for the nitrogen atoms of the target guanines. Cisplatin can bond more tightly with nitrogen because nitrogen balances the platinum charge more effectively than chlorine. It is this adduct-induced DNA bend that allows binding of proteins which contain the high mobility group, HMG domain. Once the protein is bound to the DNA, it inserts a wedge-like phenyl group of phenylalanine 37 into the widened minor groove created by the bend. The tightly bound HMG protein causes destacking of the nucleotide bases, resulting in the DNA helix becoming kinked. In this way, Cisplatin can be thought of as a monkey wrench in the DNA repair system. With the HMG protein bound to the DNA, the modified strand is not repaired properly and so the cell dies. The success of Cisplatin depends on its ratio of efficacy between cancerous and healthy cells.

An Abdominoplasty (commonly referred to as a “Tummy Tuck”) removes excess fat and skin around your abdomen to shape and contour your midsection. During surgery, I also restore weakened or separated muscles to help create an abdominal profile that is both; smoother and more firm. ⁠
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Watch this video as we go from the operating table to her 2-month post-op results! ⁠
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If you’re interested in learning more about tummy tuck surgery or any other services we offer, please DM us or give us a call today! ⁠
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☎️(424) 266-4181
🌐DrJohnDiaz.com

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Physical Exam and Sample History

Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Insulin helps keeps your blood sugar level from getting too high (hyperglycemia) or too low (hypoglycemia). The cells in your body need sugar for energy. However, sugar cannot go into most of your cells directly. After you eat food and your blood sugar level rises, cells in your pancreas (known as beta cells) are signaled to release insulin into your bloodstream. Insulin then attaches to and signals cells to absorb sugar from the bloodstream. Insulin is often described as a “key,” which unlocks the cell to allow sugar to enter the cell and be used for energy.

A positive Speed's test result is usually thought to suggest inflammation or lesions related to the biceps/labral complex. The specificity, sensitivity, and positive and negative predictive values are determined for the Speed's test.

According to a Danish study , frequent sex may help prevent pre-eclampsia. Researchers believe it's because of a protein found in sperm that can regulate the body's immune system. Yet because the cause of preeclampsia is unknown, it's important to keep your prenatal visits and talk to your doctor about your risk.

Straight Leg Raising from the USMLE collection

The thyroid is a butterfly shaped gland overlying the voice box and the windpipe. Adjacent to the thyroid are the parathyroid glands which control the body's calcium and the recurrent laryngeal nerves that control the voice box muscles. The thyroid is removed while preserving the recurrent laryngeal nerves and the parathyroids.

Minimally Invasive Surgery (MIS) Hip Joint Replacement is an advancement in hip replacement that offers important advantages over standard surgical procedures. Stryker has partnered with surgeons worldwide to develop MIS procedures and surgical instruments that are designed to help your surgeons do their very best to help you recover your lifestyle. These techniques bring together a wide variety of hip implants, new minimally invasive surgical techniques, and new instrumentation. The direct anterior approach is one of the minimally invasive techniques used in hip replacement surgery. Continuing orthopaedic experience suggests that this procedure may offer several advantages over the more traditional surgical approaches to hip replacement.1 Traditional hip replacement techniques involve operating from the side (lateral) or the back (posterior) of the hip, which requires a significant disturbance of the joint and connecting tissues and an incision approximately 8-12 inches long. In comparison, the direct anterior approach requires an incision that is only 3-4 inches in length and located at the front of the hip.1 In this position, the surgeon does not need to detach any of the muscles or tendons.

Heart failure, sometimes known as congestive heart failure, occurs when your heart muscle doesn't pump blood as well as it should. Certain conditions, such as narrowed arteries in your heart (coronary artery disease) or high blood pressure, gradually leave your heart too weak or stiff to fill and pump efficiently.

Posterior Urethral Strictures Associated with Urinary Incontinence after Prostatectomy Management

Neck and Cardiac Exam

Simple or Total Mastectomy. The entire breast is removed, but no lymph nodes are taken in this procedure. Simple mastectomy is most frequently used for further cancer prevention or when the cancer has not spread to the lymph nodes.Oct 29, 2014

This video discusses knee arthritis, and when to do osteotomy, partial knee replacement, or total knee replacement.

Mommy Makeover plastic surgery in NYC and is a fairly new phenomena. This video, from 5thavenue surgery; http://www.5thavesurgery.com, goes through a case study of a patient getting plastic surgery in NYC. Check out what a Mommy Makeover can do for your body and what Plastic Surgery can do for you.

Move the person beyond striking distance of the snake. Have the person lie down with wound below the heart. Keep the person calm and at rest, remaining as still as possible to keep venom from spreading. Cover the wound with loose, sterile bandage

this video shows the Supine assessment of reflexes

TV interview with Dr. Mostafa Yakoot, MD discussing latest researches on herbal drugs

Scott Geller MD of Fort Myers Florida uses A LASAG Yag laser is in thermal mode, 1.5 Joules/pulse to treat the trabecular meshwork between the cornea and iris for glaucoma. The view is of the inside anterior eyeball.