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Aplastic anemia is a hematopoietic disorder caused due to T lymphocyte mediated destruction of stem cells resulting in pancytopenia with a cellular bone marrow and normal cell cytogenetics. The causes of aplastic anaemia may be inherited or acquired. The causes and the diagnostic approach, along with spectrum of severity of this disorder is discussed in this presentation. A detailed discussion of the management options, along with pharmacological therapy and supportive therapy in these cases is also discussed. The treatment options include, in addition to a stem cell transplant, anti-thymocyte globulin, cyclosporine, methyprednisolone and eltrombopag (for patients who have failed treatment on combined modality therapy with ATG and cyclosporine)
Very small currents can be imperceptible. Larger current passing through the body may make it impossible for a shock victim to let go of an energized object. Still larger currents can cause fibrillation of the heart and damage to tissues. Death caused by an electric shock is called electrocution.
A brief description of the pathophysiology, clinical features, warning signs, diagnosis and management of Dengue fever. This description is based on the World Health Organisation guidelines of the management of Dengue fever.
Usually a sebaceous cyst grows very slowly and doesn't cause pain. However, they can become inflamed or infected, with the overlying skin becoming red, tender, and sore. Sometimes, they occur on a site that is constantly irritated, such as a cyst on your neck that rubs against your collar.