Asthma was originally described as an inflammatory disease that predominantly involves the central airways. Pathological and physiological evidence reported during the past few years suggests that the inflammatory process extends beyond the central airways to the peripheral airways and the lung parenchyma. The small airways are capable of producing T-helper-2 cytokines, as well as chemokines, and they have recently been recognized as a predominant site of airflow obstruction in asthmatic persons. The inflammation at this distal site has been described as more severe than large airway inflammation. These findings are of great clinical significance, and highlight the need to consider the peripheral airways as a target in any therapeutic strategy for treatment of asthma.

Many people don't know that they have hepatitis C until they already have some liver damage. This can take many years. Some people who get hepatitis C have it for a short time and then get better. This is called acute hepatitis C. But most people who are infected with the virus go on to develop long-term, or chronic, hepatitis C. Although hepatitis C can be very serious, most people can manage the disease and lead active, full lives.

Laparoscopic surgery is now commonly used as a type of minimally invasive surgery, but what is it and why is it used?

Interested in learning more about minimally invasive techniques, or having surgery planned? Visit https://www.topdoctors.co.uk/doctor/charles-imber

✔ Follow us on Instagram: https://bit.ly/3fSrqXb
✔ Follow us on Facebook: https://bit.ly/3t5kGsW
✔ Follow us on Twitter: https://bit.ly/39TidKh

Get my book on fixing injury here:
https://www.amazon.com/Rebuild....ing-Milo-Foundation-

Get my book 'The Squat Bible' here:
https://www.amazon.com/Squat-B....ible-Ultimate-Master

Get my 13-Week Squat Program? https://marketplace.trainheroi....c.com/workout-plan/p

Get olympic weightlifting programming (part 1):
https://marketplace.trainheroi....c.com/workout-plan/p

Get olympic weightlifting programming (part 2): https://marketplace.trainheroi....c.com/workout-plan/p

______________________
Show Sponsors

- TYR: https://www.tyr.com/?gclid=Cjw....KCAjw9qiTBhBbEiwAp-G

- Bandbell: Check out their amazing bars here: https://www.bandbell.com/?utm_source=youtube.com&utm_medium=web&utm_campaign=squatu

______________________
Subscribe to the channel: https://tinyurl.com/y2eq7kpr

Check out the Eleiko products I use here: https://shop.eleiko.com/en-us/?ref=qg8uBQd3JL7S

Recommended products: https://squatuniversity.com/recommended-products/

FitMap: https://www.fitmaptrainer.com/

Support SquatU & join monthly live Q&A: https://www.patreon.com/SquatUniversity

______________________

Connect with SquatUniversity:
Visit the website: http://www.squatuniversity.com
Like the Facebook page: https://www.facebook.com/SquatUniversity
Follow on Twitter: https://twitter.com/squatuniversity
Follow on TikTok: @SquatUniversity
Follow on Instagram: http://instagram.com/squat_university
Listen to the Podcast on: apple iTunes, Overcast, Pocket Casts, Google Play and the Anchor App

Shout out @Muscle and Motion for the amazing anatomy graphics.

______________________

Surgeons at The Children’s Hospital of Philadelphia were the first to perform a bilateral hand transplant on a child. Our research and work in this groundbreaking field of medicine led us to establish the Hand Transplantation Program. Combining the expertise of the Penn Transplant Institute and the Hospital’s Division of Plastic and Reconstructive Surgery and Division of Orthopedics, the program aims to improve quality of life for children who may benefit from this procedure. This is Zion, one year after the surgery

When you get a kidney transplant, a healthy kidney is placed inside your body to do the work your own kidneys can no longer do. On the plus side, there are fewer limits on what you can eat and drink, but you should follow a heart-healthy diet. Your health and energy should improve. In fact, a successful kidney transplant may allow you to live the kind of life you were living before you got kidney disease. Studies show that people with kidney transplants live longer than those who remain on dialysis. On the minus side, there are the risks of surgery. You will also need to take anti-rejection medicines for as long as your new kidney is working, which can have side effects. You will have a higher risk for infections and certain types of cancer.

A talus fracture is a break in one of the bones that forms the ankle. This type of fracture often occurs during a high-energy event, such as a car collision or a high-velocity fall. Because the talus is important for ankle movement, a fracture often results in significant loss of motion and function. In addition, a talus fracture that does not heal properly can lead to serious complications, including chronic pain. For this reason, many talus fractures require surgery.

Patent ductus arteriosus (PDA) is a persistent opening between two major blood vessels leading from the heart. The opening, called the ductus arteriosus, is a normal part of a baby's circulatory system before birth that usually closes shortly after birth. If it remains open, however, it's called a patent ductus arteriosus.

Watch that video to know if it is safe to have intercourse during her period

First aid - Shock and bleeding

Postmenopausal bleeding (PMB) is defined for practical purposes as vaginal bleeding occurring after twelve months of amenorrhoea, in a woman of the age where the menopause can be expected.[1] Hence it does not apply to a young woman, who has had amenorrhoea from anorexia nervosa, or a pregnancy followed by lactation. However, it can apply to younger women following premature ovarian failure or premature menopause. Unscheduled bleeding in women of menopausal age taking hormone replacement therapy (HRT) should be managed in the same way from a practical perspective.[2] 'Unscheduled bleeding' is defined as non-cyclical bleeding still continuing six months after commencing HRT or after six months of amenorrhoea.

Knee replacement involves replacing a knee joint that has been damaged or worn away, usually by arthritis or injury. Find out more here: https://www.bupa.co.uk/health-....information/knee-cli

Find Out More at https://medwayhealthcare.com/

A pilonidal sinus (PNS) is a small cyst or abscess that occurs in the cleft at the top of the buttocks. A PNS usually contains hair, dirt, and debris. It can cause severe pain and can often become infected. If it becomes infected, it may ooze pus and blood and have a foul odor. A PNS is a condition that mostly affects men and is also common in young adults. It’s also more common in people who sit a lot, like cab drivers.

How To Breastfeed - Deep Latch Technique

Vasculitis is an inflammation of your blood vessels. It causes changes in the walls of blood vessels, including thickening, weakening, narrowing and scarring. These changes restrict blood flow, resulting in organ and tissue damage. There are many types of vasculitis, and most of them are rare. Vasculitis might affect just one organ, such as your skin, or it may involve several. The condition can be short term (acute) or long lasting (chronic). Vasculitis can affect anyone, though some types are more common among certain groups. Depending on the type you have, you may improve without treatment. Or you will need medications to control the inflammation and prevent flare-ups. Vasculitis is also known as angiitis and arteritis.

A seizure occurs when there’s abnormal electrical activity in the brain. Seizures may go virtually unnoticed. Or, in severe cases, they may produce a change or loss of consciousness and involuntary muscle spasms called convulsions. Seizures usually come on suddenly and vary in duration and severity. A seizure may be a one-time event, or you may have seizures repeatedly. Recurrent seizures are called epilepsy, or a seizure disorder. Less than one in 10 people who has a seizure develops epilepsy. Experts classify seizures into two general categories and many subtypes based on the pattern of the attack. Generalized seizures involve both sides of the brain from the start of the attack. Common subtypes include tonic-clonic (grand mal) and absence seizures (petit mal). Febrile and infantile spasms are two types of generalized seizures that occur almost exclusively in young children. Partial (or focal) seizures are the second major seizure type. These begin in a specific area of the brain and may be contained there. Or they may spread to the entire brain. With simple partial seizures, the person remains conscious. Complex partial seizures involve impaired consciousness. What Causes Seizures? Often the cause of a seizure is unknown. Many conditions can provoke seizures, including: Stroke Brain tumors Head injuries Electrolyte imbalance Very low blood sugar Repetitive sounds or flashing lights, such as in video games Medications, such as antipsychotics and some asthma drugs Withdrawal from medications, such as Xanax, narcotics, or alcohol Use of drugs such as cocaine and heroin Cancer Brain infections, such as meningitis

Bizarre Body Modifications

Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Insulin helps keeps your blood sugar level from getting too high (hyperglycemia) or too low (hypoglycemia). The cells in your body need sugar for energy. However, sugar cannot go into most of your cells directly. After you eat food and your blood sugar level rises, cells in your pancreas (known as beta cells) are signaled to release insulin into your bloodstream. Insulin then attaches to and signals cells to absorb sugar from the bloodstream. Insulin is often described as a “key,” which unlocks the cell to allow sugar to enter the cell and be used for energy.