Removal of the womb by keyhole surgery. The womb is detached from its pelvic attachments and removed through the birth canal. The birth canal is then stitched closed.

Cisplatin is in a class of drugs known as platinum-containing compounds used to treat various types of cancers including metastatic testicular and ovarian tumors. The molecule was first discovered in 1845, but did not receive FDA approval until 1978. Today it is known as the "penicillin of cancer drugs," because it is so effective for many different cancers. There are three key players involved in Cisplatin's mechanism: (1) Cisplatin, (2) DNA (3) and an HMG Protein. Most Cisplatin enters the body through active transport, but some molecules are passively defused through the cell membrane. Once in the nucleus, Cisplatin can form an adduct with two consecutive guanine bases within a strand of DNA. The molecule loses its chlorine atoms in exchange for the nitrogen atoms of the target guanines. Cisplatin can bond more tightly with nitrogen because nitrogen balances the platinum charge more effectively than chlorine. It is this adduct-induced DNA bend that allows binding of proteins which contain the high mobility group, HMG domain. Once the protein is bound to the DNA, it inserts a wedge-like phenyl group of phenylalanine 37 into the widened minor groove created by the bend. The tightly bound HMG protein causes destacking of the nucleotide bases, resulting in the DNA helix becoming kinked. In this way, Cisplatin can be thought of as a monkey wrench in the DNA repair system. With the HMG protein bound to the DNA, the modified strand is not repaired properly and so the cell dies. The success of Cisplatin depends on its ratio of efficacy between cancerous and healthy cells.

Scott Geller MD of Fort Myers Florida uses A LASAG Yag laser is in thermal mode, 1.5 Joules/pulse to treat the trabecular meshwork between the cornea and iris for glaucoma. The view is of the inside anterior eyeball.

Patty Jackson WDAS Interviews Renee Brown & Nnamdi G. Osuagwu, Co-Founders of The Fibroids Project (FibroidsProject.com).

Can a Vaccine Give Me the Disease It’s Supposed to Protect Me Against?

Laparotomy (opening and closing)

this video shows the Supine assessment of reflexes

Neck and Cardiac Exam

A video showing the phases of normal wound healing

Posterior Urethral Strictures Associated with Urinary Incontinence after Prostatectomy Management

Straight Leg Raising from the USMLE collection

What Is It? Your wisdom teeth (third molars) usually start to erupt (enter your mouth) during the late teen years. Sometimes, there's not enough room for them. They may come into your mouth partially or not at all. Partial eruption of a wisdom tooth can create a flap of gum tissue next to the tooth. The flap can trap bits of food and debris. It can turn into a hotbed for bacteria. It's called pericoronitis if the tissue around the tooth becomes inflamed. Pericoronitis also can occur around a wisdom tooth that is still completely under the gums. Symptoms Symptoms include: Painful, swollen gum tissue in the area of the affected tooth. It can be difficult to bite down comfortably without catching the swollen tissue between your teeth. A bad smell or taste in the mouth Discharge of pus from the gum near the tooth More serious symptoms include: Swollen lymph nodes under your chin (the submandibular nodes) Muscle spasms in the jaw Swelling on the affected side of the face Diagnosis Usually, someone with pericoronitis goes to the dentist, complaining of pain in the area of the back tooth. Pericoronitis is diagnosed during the clinical exam. Your dentist will see inflamed gum tissue in the area of the unerupted or partly erupted wisdom tooth. The gums may be red, swollen or draining fluid or pus. Expected Duration Pericoronitis can be managed with antibiotics and warm salt water rinses. It goes away in about one week. However, it can return. This is likely to happen if the tooth does not completely enter the mouth and food and bacteria keep building up under the gum. Prevention You can help to prevent pericoronitis by brushing any erupting wisdom tooth and flossing around it. This will help make sure that food and bacteria do not build up under the gums. However, sometimes these steps do not work. If pericoronitis returns, you may need to have the flap of gum tissue removed. In some cases, the flap of tissue grows back and the wisdom tooth will need to be extracted. Treatment Pericoronitis can be tricky to treat. That's because the flap of gum tissue won't go away until the wisdom tooth emerges naturally, the tissue is removed or the tooth is removed. Your dentist will clean the area thoroughly by rinsing under the flap with water to remove bits of food and pus. Your dentist also may need to remove damaged tissue. If the area is infected, you'll most likely be given antibiotics. Your dentist will explain how to keep the area clean, which is the best way to prevent the problem from returning. This usually involves brushing and flossing daily and rinsing your mouth with water several times a day. These steps will help to prevent food from getting stuck under the gum flap. In some cases, your dentist may suggest removing the erupting tooth. Or the dentist may want to remove the tooth above it, which bites down on the gum below. If your dentist thinks the tooth may erupt fully into the mouth without problems, he or she may leave it alone. However, if pericoronitis comes back, the tooth may be extracted. Pericoronitis that causes symptoms should be treated as soon as possible. If it is not, the infection can spread to other areas of your mouth. The most severe cases are treated in a hospital. They sometimes require intravenous antibiotics and surgery. When To Call a Professional If you have symptoms of pericoronitis, make an appointment to see your dentist. If your wisdom teeth are coming in, visit your dentist at least twice a year for regular checkups. During those visits, the dentist can check on the progress of your wisdom teeth. Prognosis Pericoronitis does not cause any long-term effects. If the affected tooth is removed or erupts fully into the mouth, the condition cannot return.

Treatment consists of diet modifications and laxatives A high-fiber diet can be effective, along with over-the-counter medications, such as stool softeners. In some cases, a medical procedure to remove the hemorrhoid may be needed to provide relief.

Physical Exam and Sample History

The thyroid is a butterfly shaped gland overlying the voice box and the windpipe. Adjacent to the thyroid are the parathyroid glands which control the body's calcium and the recurrent laryngeal nerves that control the voice box muscles. The thyroid is removed while preserving the recurrent laryngeal nerves and the parathyroids.

An Abdominoplasty (commonly referred to as a “Tummy Tuck”) removes excess fat and skin around your abdomen to shape and contour your midsection. During surgery, I also restore weakened or separated muscles to help create an abdominal profile that is both; smoother and more firm. ⁠
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Watch this video as we go from the operating table to her 2-month post-op results! ⁠
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If you’re interested in learning more about tummy tuck surgery or any other services we offer, please DM us or give us a call today! ⁠
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☎️(424) 266-4181
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Cervical cerclage can be placed via transvaginal, open transabdominal, or laparoscopic transabdominal approach, preferably before pregnancy. Recurrent late miscarriages may be due to a weak (sometimes called an incompetent) cervix that shortens or opens too early in pregnancy. Cervical cerclage involves placing a stitch around the upper part of the cervix to keep it closed; the operation may be carried out through the vagina, or through the abdomen, as an open or laparoscopic ('keyhole') procedure.

Pulmonary alveolar proteinosis. Please see disclaimer on my website. www.academyofprofessionals.com. MCQs are also available.

USMLE Step 2 CS - Diabetes Mellitus This is just preview video. To get full access please visit our website : www.usmletutoring.com

Dr. Thomas Haas, MD, Board Certified plastic surgeon, performed breast augmentation on his patient in November, 2007. The surgery was performed in his JCAHO accredited in-office Surgery Suite (Imaage) located in Louisville, Kentucky. With so many women interested in this surgery, this video can answer many of their questions. Dr. Haas specializes in cosmetic and aesthetic surgery and has been in practice over 15 years