Ca2+ binds with the membrane of the synaptic vesicles, which causes the vesicles to break and release the neurotransmitter into the synaptic cleft. After the neurotransmitters are released, they diffuse across the synaptic cleft and interact with receptors on the postsynaptic membrane. When the action potential reaches the presynaptic terminal, it provokes the release of a small quantity of neurotransmitter molecules, which bind to chemical receptor molecules located in the membrane of another neuron, the postsynaptic neuron, on the opposite side of the synaptic cleft.

Ischemic colitis occurs when blood flow to part of the large intestine (colon) is reduced, usually due to narrowed or blocked blood vessels (arteries). The diminished blood flow doesn't provide enough oxygen for the cells in your digestive system. Ischemic colitis can cause pain and may damage your colon. Any part of the colon can be affected, but ischemic colitis usually causes pain on the left side of the belly area (abdomen). The condition can be misdiagnosed because it can easily be confused with other digestive problems. Ischemic colitis may heal on its own. But you may need medication to treat ischemic colitis or prevent infection, or you may need surgery if your colon has been damaged. Symptoms ShareTweet Oct. 13, 2015 References Products and Services Newsletter: Mayo Clinic Health Letter See also Abdominal pain Colonoscopy Color Blue Detects Colon Cancer CT scan CT scans: Are they safe? Diarrhea Ultrasound Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship PolicyOpportunitiesAd Choices Mayo Clinic Store Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. NEW! – The Mayo Clinic Diet, Second Edition Treatment Strategies for Arthritis Mayo Clinic on Better Hearing and Balance Keeping your bones healthy and strong The Mayo Clinic Diet Online Ads by Swoop Psoriasis Treatment www.informationaboutpsoriasis.com Explore a Treatment Option for Moderate to Severe Plaque Psoriasis Immune Biomarker PD-L1 - Discover the Science iobiomarkers.bmsinformation.com Understanding Assay Results for PD-L1 is Crucial for Treatment Decisions. Biomarker PD-L1 Information - Easy to Download Resources iobiomarkers.bmsinformation.com Explore the Role of PD-L1 in Immuno-Oncology & the Evolving Biomarker Landscape.

The video is a clip from ABC 7 News, KGO-TV. The video details the new FDA approved device Insight eNO system which uses exhaled nitric oxide for effective asthma management, in both adults and children.
Insight eNO has revolutionized asthma treatment. Apieron’s asthma products help in managing asthma for patients suffering from acute asthma attacks by detecting exhaled nitric oxide (eNO) present in the human breath.

This video describe the clinical managment of a patient with hyperprolactinemia, including the approach to diagnosis, important endocrine testing, and management options.

-MEN1 syndrome is composed of hyperparathyroidism, gastrinoma (pancreatic tumor) and pituitary tum or(remember the 3 Ps). Hyperparathyroidism in MEN1 is caused by hyperplasia of the parathyroid glands. Removal of 3 1/2 glands or total parathyroidectomy with autotransplantation is necessary.

PARASITE REMOVED FROM THE EYEBALL OF A YOUNG N, NOT FOR THE SCREAMISH!Loa Loa worms (also known as the "eye worm") are classified as filarial worms, meaning they thrive in human tissue. The Loa Loa worm is also called the "eye worm" because they often migrate through the eye and surrounding subsurface areas. At one time, prior to the 1920s, loa loa worm infections occurred in the United States. Today, however, they mainly infect people who are native to Sudan, and those who live in or near Central and West Africa's swamps and rain forests.

Loiasis is the infestation of loa loa worms in humans. The larvae are first collected from an infected individual when a mango fly (horsefly) or a deer fly bites the individual, and acquires the larvae. The larvae then progress through the fly's body, finally reaching the feeding tube. They are then transferred to a human host when the fly bites the human. The larvae may remain unnoticed for months or years before becoming an adult, mating, and producing offspring.

Adult female Loa Loa worms can reach a length of 2 1/2 inches while males are approximately half that size. Loa Loa worms can live approximately fifteen years inside their human hosts. They travel continuously through connective and deep tissue, often without the victim experiencing any sensation other than occasional itching.

It is when the worm slows or reaches a sensitive spot that a person will often feel the greatest discomfort. At this point, immune reactions may also include localized redness and a condition called "Calabar" swelling. Skin eruptions and muscle pain may be evident.

When the Loa Loa worm reaches the eye tissue, it can be easily seen and felt within the eyeball for up to an hour. It is usually removed under local anesthesia if the patient is within proximity of a qualified physician. When an adult worm dies, the surrounding tissue may abscess and require excision. Encephalitis can occur if the worm reaches the brain.

After mating, the female will deposit eggs - called microfilariae. These tiny organisms then travel in a worm-like fashion in the bloodstream during daytime hours, when potential host flies are most abundant. They congregate in the lungs at night.

A Loa Loa worm infection is rarely fatal and treatments often cause more life-threatening side effects than the actual infestation, especially if the worms are widespread. The most common treatments are DEC (diethylcarbamazine) and Ivermectin

Polycythemia vera (pol-e-sigh-THEE-me-uh VEER-uh) is a slow-growing type of blood cancer in which your bone marrow makes too many red blood cells. Polycythemia vera may also result in production of too many of the other types of blood cells — white blood cells and platelets. These excess cells thicken your blood and cause complications, such as such as a risk of blood clots or bleeding. Polycythemia vera isn't common. It usually develops slowly, and you may have it for years without noticing signs or symptoms. Often, polycythemia vera is found during a blood test done for some other reason. Without treatment, polycythemia vera can be life-threatening. However, with proper medical care, many people experience few problems related to this disease. Over time, there's a risk of progressing to more-serious blood cancers, such as myelofibrosis or acute leukemia.

Watch that video of Female Genital Infection Causes and Symptoms

This video: Polycystic ovary syndrome (PCOS) is a common endocrine disorder among women of reproductive age. Women with PCOS may have enlarged ovaries that contain small collections of fluid — called follicles — located in each ovary as seen during an ultrasound exam. Infrequent or prolonged menstrual periods, excess hair growth, acne, and obesity can all occur in women with polycystic ovary syndrome. In adolescents, infrequent or absent menstruation may raise suspicion for the condition. The exact cause of polycystic ovary syndrome is unknown. Early diagnosis and treatment along with weight loss may reduce the risk of long-term complications, such as type 2 diabetes and heart disease.

Wilson's disease is a rare inherited disorder that causes too much copper to accumulate in your liver, brain and other vital organs. Symptoms typically begin between the ages of 12 and 23. Copper plays a key role in the development of healthy nerves, bones, collagen and the skin pigment melanin. Normally, copper is absorbed from your food, and any excess is excreted through bile — a substance produced in your liver.

Review of heart sounds

USMLE Step 2 CS - Antenatal Visit This is just preview video. To get full access please visit our website : www.usmletutoring.com

The Valsalva Maneuver is any attempt to exhale with the mouth and nose closed. Named after the Italian physician and anatomist, Antonio Maria Valsalva (1666-1723), it is also known as Valsalva's Test and Valsalva's Method.

Bugs Removal from Ear Canal

Babinski reflex

DMC Surgeon uses minimally-invasive surgery to remove uterine fibroids to hasten recovery. ~ Detroit Medical Center

DMC Neurosurgeon Sandeep Mittal uses EEG and brain surgery to decode the secrets of adult epilepsy - Part I of a two-part series. ~ Detroit Medical Center

Learn How to Suture a Banana

A new promising technique in saving the lives of patients with cancer of the esophagus. It is minimally invasive and the recovery time is quicker than ever. H. Lee Moffitt Cancer Center

A bone marrow biopsy is part of a bone marrow test that takes a sample of your solid bone tissue. This test looks for abnormalities in your blood cells and signs of any diseases. You can request anesthesia or a sedative before the biopsy, and manage any pain afterward with over-the-counter medications.