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Genetic surfactant dysfunction disorders are caused by mutations in genes encoding proteins critical for the production and function of pulmonary surfactant. These rare disorders may produce familial or sporadic lung disease, with clinical presentations ranging from neonatal respiratory failure to childhood- or adult-onset interstitial lung disease. An overview of these disorders is presented in the table.. Interstitial lung diseases in children until recently were categorized by their histologic appearance in a manner similar to that used for adult forms of interstitial lung disease (ILD). In children, the lung histopathology findings associated with desquamative interstitial pneumonitis (DIP) are now known to often result from genetic mechanisms that disrupt normal surfactant production and metabolism. By contrast, DIP in adults is considered to represent a distinct type of ILD, which is strongly associated with cigarette smoking and carries a relatively favorable prognosis [1]. These genetic disorders also result in histopathologic patterns other than DIP, including findings of pulmonary alveolar proteinosis and chronic pneumonitis of infancy. An understanding of the pathogenesis of these disorders permits a mechanistic classification as genetic surfactant dysfunction disorders instead of their previous classification based upon histologic appearance.
A sleep disorder, or somnipathy, is a medical disorder of the sleep patterns of a person or animal. Some sleep disorders are serious enough to interfere with normal physical, mental, social and emotional functioning. Polysomnography and actigraphy are tests commonly ordered for some sleep disorders.
The etiology of BOO is diverse and definitely gender specific. Often anatomic causes induce functional abnormality that remains somewhat unique for each individual, regardless of sex. A full appreciation of the possible etiologies of obstruction is necessary in order to identify overt and more subtle scenarios. In women, iatrogenic causes of obstruction are the most common. Other entities account for far fewer of the cases. The obstruction evaluation in women is somewhat more diverse in terms of modalities used, with no single grouping of techniques that are generally apropos. Individualized evaluation remains a tenet of analysis, and urodynamic criteria used to diagnose BOO in women continue to evolve.
Shaken baby syndrome symptoms and signs include: Extreme irritability Difficulty staying awake Breathing problems Poor eating Tremors Vomiting Pale or bluish skin Seizures Paralysis Coma Other injuries that may not be initially noticeable include bleeding in the brain and eye, damage to the spinal cord and neck and fractures of the ribs, skull and bones. Evidence of prior child abuse also is common.
The difference between bronchitis and pneumonia is that bronchitis causes an inflammation of the air passages while pneumonia causes fluid in the lungs due to an infection. The common cold however, allows people to remain active and presents itself with a clear runny nose, cough, and a low-grade or no fever.
Gestational hypertension, also referred to as pregnancy induced hypertension (PIH) is a condition characterized by high blood pressure during pregnancy. Gestational hypertension can lead to a serious condition called preeclampsia, also referred to as toxemia. Hypertension during pregnancy affects about 6-8% of pregnant women.
While it is unclear whether high heel shoes may or may not cause back pain, it is common for high heels to exacerbate an already present spinal condition. ... This pain in the back may also result from foot or leg fatigue that results from wearing these shoes and this can affect whole body mechanics.
A surgeon begins the PPH stapled hemorrhoidectomy by inserting a circular anal dilator and obturator into the anal canal and then securing the dilator in place with four sutures. The surgeon then inserts a PPH anoscope into the obturator. Next, he places a circumferential purse-string suture of 2-0 Monocryl on a UR-6 needle 4 cm proximal to the dentate line. The surgeon opens a PPH stapler and places its anvil across the purse string. The stapler is then closed and fired; it is held closed for two minutes to improve hemostasis. Prior to firing the stapler in a female patient, the surgeon places a gloved finger in the vagina to ensure the vaginal mucosa and rectal-vaginal septum are not trapped within the jaws of the closed stapler. The surgeon then opens and removes the stapler.
Cartilage is a slippery tissue that provides a smooth surface for joint motion and acts as a cushion between the bones. Synovium is soft, and it lines the joints. It produces fluid, called synovial fluid, for lubrication, and it supplies nutrients and oxygen to the cartilage. As these functions break down, they no longer protect the bones of the knee joint, and bone damage occurs. OA of the knee can cause pain and stiffness. The symptoms worsen over time
Cholangitis Email this page to a friend Email this page to a friend Facebook Twitter Google+ Cholangitis is an infection of the bile ducts, the tubes that carry bile from the liver to the gallbladder and intestines. Bile is a liquid made by the liver that helps digest food. Causes Cholangitis is most often caused by bacteria. This can occur when the duct is blocked by something, such as a gallstone or tumor. The infection causing this condition may also spread to the liver. Risk factors include a previous history of gallstones, sclerosing cholangitis, HIV, narrowing of the common bile duct, and rarely, travel to countries where you might catch a worm or parasite infection. Symptoms The following symptoms may occur: Pain on the upper right side or upper middle part of the abdomen. It may also be felt in the back or below the right shoulder blade. The pain may come and go and feel sharp, cramp-like, or dull. Fever and chills. Dark urine and clay-colored stools. Nausea and vomiting. Yellowing of the skin (jaundice), which may come and go.
The vulvar vaginal diseases service sees referrals to help women with short--and long--term problems of the outer genital area (vulva), vagina and pelvic floor muscles including: Vulvar vaginal burning, itching, irritation and pain Vulvar Vestibulitis Pain with intercourse Discharge Yeast infections Bacterial vaginosis Pelvic floor muscle dysfunction A patient must be referred by her local health care provider. Services include: Skin care education Examinations-Your healthcare provider will examine you and talk with you about recommendations for treatment and/or management of your symptoms. Some vulvar diseases require a biopsy to diagnose the condition. Referrals-Your healthcare team may refer you to other specialists, including physical therapists or health psychologists. Separate insurance authorization is necessary for these services. The clinic staff provides general education and support to help women cope with these very personal health problems. Following a clinic visit, a letter is promptly sent to your local health care provider. The letter provides the results of your exam and the plan of care.