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Primary sclerosing (skluh-ROHS-ing) cholangitis (koh-lan-JIE-tis) is a disease of the bile ducts, which carry the digestive liquid bile from your liver to your small intestine. In primary sclerosing cholangitis, inflammation causes scars within the bile ducts. These scars make the ducts hard and narrow and gradually cause serious liver damage. In most people with primary sclerosing cholangitis, the disease progresses slowly and can lead to liver failure, repeated infections, and tumors of the bile duct or liver. Liver transplant is the only known cure for primary sclerosing cholangitis. The search for other treatments to slow or stop primary sclerosing cholangitis is ongoing, and scientists have turned up many promising leads. Until better treatments are proved safe and effective, though, care for primary sclerosing cholangitis focuses on monitoring liver function, managing symptoms and, when possible, doing procedures that temporarily open blocked bile ducts.
There is a strong association with obesity. In children younger than 10 years, it is associated with metabolic endocrine disorders {hypothyroidism, panhypopituitarism, hypogonadism, renal osteodystrophy, growth hormone abnormalities). SCFE is considered chronic if it has been present more than 3 weeks and acute if it has been present for 3 weeks or less. It is called "stable" if the patient can bear weight and "unstable" if the patient cannot ambulate. Unstable SCFE is associated with more complications, including avascular necrosis of the femoral head (AVN). SCFE is diagnosed by x-ray of the pelvis and bilateral hips. The underlying cause is a widened epiphyseal growth plate, due to abnormal cartilage maturation and endochondral ossification. The treatment is surgical, requiring immediate internal fixation with a single screw. Delay in treatment {> 24 hours) leads to increased AVN, SCFE progression from stable to unstable, and high risk of future degenerative arthritis. Prophylactic contralateral fixation of the unaffected hip is not routinely done in the U.S., except in patients with endocrine abnormalities.
- Group A streptococcal pharyngitis Classic physical examination findings include tonsillar exudates, tender anterior cervical lymphadenopathy, and palatal petechiae. Diagnosis should be confirmed with throat culture (preferred) or rapid antigen testing prior to initiation of antibiotics.
In this medical video: This 72-year-old patient was unable to resist blinking when we tapped on the glabella. This is the glabellar reflex or Myerson's sign . It is often an early sign of Parkinson's disease, but can also be seen in early dementia as well as other progressive neurologic illness. Note the left (i.e., asymmetrical) hand resting tremor.
Obesity is the abnormal condition that causes a person to put on excessive amounts of weight due to accumulation of fat in their body. This extreme weight causes a variety of other disorders and diseases as complications associated with it. https://goo.gl/GgSAoY
The primary goal of treatment for each patient is to help relieve pain and other symptoms resulting from the herniated disc. To achieve this goal, each patient’s treatment plan should be individualized based on the source of the pain, the severity of pain and the specific symptoms that the patient exhibits.
Tooth loss can make you look older. When you lose a tooth and don’t replace it with a dental implant, you risk the chance of jawbone loss. Normally, your tooth root stimulates the continued growth and health of your jawbone. Dental implants mirror your natural tooth root and keep your jawbone healthy.
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