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Immunohistochemistry or IHC refers to the process of detecting antigens (e.g., proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues.[1] IHC takes its name from the roots "immuno," in reference to antibodies used in the procedure, and "histo," meaning tissue (compare to immunocytochemistry). Immunohistochemical staining is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors. Specific molecular markers are characteristic of particular cellular events such as proliferation or cell death (apoptosis). IHC is also widely used in basic research to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of a biological tissue. Visualising an antibody-antigen interaction can be accomplished in a number of ways. In the most common instance, an antibody is conjugated to an enzyme, such as peroxidase, that can catalyse a colour-producing reaction. Alternatively, the antibody can also be tagged to a fluorophore, such as fluorescein or rhodamine
How to use a Syphilis rapid test kit for self-diagnosis of Syphilis (fingerstick blood). Convenient, Easy to Use, and over 99% Accurate. Certified GMP and ISO13485. Test yourself at home with Complete Privacy. Buy online today at: http://www.stdrapidtest.com
Diabetes is a growing global health concern, as is obesity. Diabetes and obesity are intrinsically linked: obesity increases the risk of diabetes and also contributes to disease progression and cardiovascular disease. Although the benefits of weight loss in the prevention of diabetes and as a critical component of managing the condition are well established, weight reduction remains challenging for individuals with type 2 diabetes due to a host of metabolic and psychological factors. For many patients, lifestyle intervention is not enough to achieve weight loss, and alternative options, such as pharmacotherapy, need to be considered. However, many traditional glucose-lowering medications may lead to weight gain. This article focuses on the potential of currently available pharmacological strategies and on emerging approaches in development to support the glycemic and weight-loss goals of individuals with type 2 diabetes. Two pharmacotherapy types are considered: those developed primarily for blood glucose control that have a favorable effect on body weight and those developed primarily to induce weight loss that have a favorable effect on blood glucose control. Finally, the potential of combination therapies for the management of obese patients with type 2 diabetes is discussed.
Vertigo is a sense of rotation, rocking, or the world spinning, experienced even when someone is perfectly still. Many children attempt to create a sense of vertigo by spinning around for a time; this type of induced vertigo lasts for a few moments and then disappears. In comparison, when vertigo occurs spontaneously or as a result of an injury it tends to last for many hours or even days before resolving.
Ewing's sarcoma typically occurs in children and young adults. It often begins in the legs, bones of the pelvis, and arms. Bone pain, localized swelling, and tenderness are symptoms. In rare cases bone fractures may also be found. Treatments include chemotherapy, surgery, and radiation.
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MEDICAL ANIMATION TRANSCRIPT:
Laparoscopic Ovarian Drilling (LOD)
A surgical treatment for women with PCOS
Women with PCOS usually have ovaries with a thick outer layer.
Ovarian drilling works by breaking through the thick outer surface and lowering the amount of testosterone made by the ovaries
A small incision is made in the abdomen.
Carbon dioxide gas is used to inflate the abdomen.
Very small holes are made in the ovaries.
Ovarian drilling can help restore ovulation and improve the chances of becoming pregnant.
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*TimeStamps*
0:00 Introduction
0:15 Procedure of Laparoscopic Ovarian Drilling (LOD)
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Let us watch this 3D video to understand what is Laparoscopic Ovarian Drilling for PCOS, why it is done, how well it works, and what to expect.
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#pcos #pcostreatment #laparascopicovariandrilling
The core features of migraine are headache, which is usually throbbing and often unilateral, and associated features of nausea, sensitivity to light, sound, and exacerbation with head movement. Migraine has long been regarded as a vascular disorder because of the throbbing nature of the pain.
The easy experimental answer to this question is 264 hours (about 11 days). In 1965, Randy Gardner, a 17-year-old high school student, set this apparent world-record for a science fair. Several other normal research subjects have remained awake for eight to 10 days in carefully monitored experiments. None of these individuals experienced serious medical, neurological, physiological or psychiatric problems. On the other hand, all of them showed progressive and significant deficits in concentration, motivation, perception and other higher mental processes as the duration of sleep deprivation increased. Nevertheless, all experimental subjects recovered to relative normality within one or two nights of recovery sleep. Other anecdotal reports describe soldiers staying awake for four days in battle, or unmedicated patients with mania going without sleep for three to four days.