#dialysis #hemodialysis #kidneys
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Dealing with burns

The goal of breast cancer surgery is to remove the entire tumor from the breast. Some of the lymph nodes in the underarm area (axillary nodes) may also be removed to see if cancer cells are present.

Ventricular septal rupture (VSR) is a rare but lethal complication of myocardial infarction (MI). The event occurs 2-8 days after an infarction and often precipitates cardiogenic shock. [1] The differential diagnosis of postinfarction cardiogenic shock should exclude free ventricular wall rupture and rupture of the papillary muscles. (See the image below.)

Anatomy of Back Muscles and Spinal Cord

Knee osteotomy is commonly used to realign your knee structure if you have arthritic damage on only one side of your knee. The goal is to shift your body weight off the damaged area to the other side of your knee, where the cartilage is still healthy. When surgeons remove a wedge of your shinbone from underneath the healthy side of your knee, the shinbone and thighbone can bend away from the damaged cartilage. Imagine the hinges on a door. When the door is shut, the hinges are flush against the wall. As the door swings open, one side of the door remains pressed against the wall as space opens up on the other side. Removing just a small wedge of bone can "swing" your knee open, pressing the healthy tissue together as space opens up between the thighbone and shinbone on the damaged side so that the arthritic surfaces do not rub against each other. Osteotomy is also used as an alternative treatment to total knee replacement in younger and active patients. Because prosthetic knees may wear out over time, an osteotomy procedure can enable younger, active osteoarthritis patients to continue using the healthy portion of their knee. The procedure can delay the need for a total knee replacement for up to ten years.

Medically: How common do females orgasm? From the medical point of view

Mitra Nejad, MD
Associate Physician Diplomate
UCLA Stein Eye Institute, Cataract and Refractive Surgery Division

McMaster University technique of Laparoscopic Radical Nephrectomy

Mitral Valve Repair of Posterior Leaflet Prolapse HD

Lumbar Laminotomy and Microdiscectomy

Endoscopic Removal of a Large Choanal Polyp

Cisplatin is in a class of drugs known as platinum-containing compounds used to treat various types of cancers including metastatic testicular and ovarian tumors. The molecule was first discovered in 1845, but did not receive FDA approval until 1978. Today it is known as the "penicillin of cancer drugs," because it is so effective for many different cancers. There are three key players involved in Cisplatin's mechanism: (1) Cisplatin, (2) DNA (3) and an HMG Protein. Most Cisplatin enters the body through active transport, but some molecules are passively defused through the cell membrane. Once in the nucleus, Cisplatin can form an adduct with two consecutive guanine bases within a strand of DNA. The molecule loses its chlorine atoms in exchange for the nitrogen atoms of the target guanines. Cisplatin can bond more tightly with nitrogen because nitrogen balances the platinum charge more effectively than chlorine. It is this adduct-induced DNA bend that allows binding of proteins which contain the high mobility group, HMG domain. Once the protein is bound to the DNA, it inserts a wedge-like phenyl group of phenylalanine 37 into the widened minor groove created by the bend. The tightly bound HMG protein causes destacking of the nucleotide bases, resulting in the DNA helix becoming kinked. In this way, Cisplatin can be thought of as a monkey wrench in the DNA repair system. With the HMG protein bound to the DNA, the modified strand is not repaired properly and so the cell dies. The success of Cisplatin depends on its ratio of efficacy between cancerous and healthy cells.

In this condition, the body retains water instead of excreting it normally in urine. This process upsets the body's balance of minerals called electrolytes, especially sodium. Symptoms can vary depending on how rapidly the condition develops. In some cases, nausea and vomiting, headache, confusion, weakness, and fatigue may be experienced. Treatments include fluid restriction and, possibly, medications to adjust electrolyte balance. Underlying conditions also need treatment.

ATTENTION! 5 Warning Signs Of BREAST CANCER That Many Women Ignore!

Hepatitis C is an infection caused by the hepatitis C virus (HCV) that attacks the liver and leads to inflammation. The World Health Organization (WHO) estimates that about 3% of the world’s population has been infected with HCV and that there are more than 170 million chronic carriers who are at risk of developing liver cirrhosis and/or liver cancer. The image below depicts the HCV genome.

Cell Adhesion Molecule Inhibition Animation

Dysmenorrhea, or chronic menstrual pain, is the most common gynecological pain condition, affecting from 45% to 95% of menstruating women. But because it is commonly considered a normal aspect of the menstrual cycle,

A spinal cord injury is not the sort of thing you have to wonder about having. If you've suffered a spinal cord injury, your life is in danger, and you'll know you're injured. You can't use symptoms to diagnose the sort of spinal cord injury you have, and every patient's prognosis is different. Some make a miraculous recovery within months; others need years of physical therapy and still make little to no progress.