Genetic surfactant dysfunction disorders are caused by mutations in genes encoding proteins critical for the production and function of pulmonary surfactant. These rare disorders may produce familial or sporadic lung disease, with clinical presentations ranging from neonatal respiratory failure to childhood- or adult-onset interstitial lung disease. An overview of these disorders is presented in the table.. Interstitial lung diseases in children until recently were categorized by their histologic appearance in a manner similar to that used for adult forms of interstitial lung disease (ILD). In children, the lung histopathology findings associated with desquamative interstitial pneumonitis (DIP) are now known to often result from genetic mechanisms that disrupt normal surfactant production and metabolism. By contrast, DIP in adults is considered to represent a distinct type of ILD, which is strongly associated with cigarette smoking and carries a relatively favorable prognosis [1]. These genetic disorders also result in histopathologic patterns other than DIP, including findings of pulmonary alveolar proteinosis and chronic pneumonitis of infancy. An understanding of the pathogenesis of these disorders permits a mechanistic classification as genetic surfactant dysfunction disorders instead of their previous classification based upon histologic appearance.

Gallbladder cancer is cancer that begins in the gallbladder. Your gallbladder is a small, pear-shaped organ on the right side of your abdomen, just beneath your liver. The gallbladder stores bile, a digestive fluid produced by your liver. Gallbladder cancer is uncommon. When gallbladder cancer is discovered at its earliest stages, the chance for a cure is very good. But most gallbladder cancers are discovered at a late stage, when the prognosis is often very poor. Gallbladder cancer is difficult to diagnose because it often causes no specific signs or symptoms. Also, the relatively hidden nature of the gallbladder makes it easier for gallbladder cancer to grow without being detected. Symptoms ShareTweet Aug. 07, 2014 References Products and Services Book: Mayo Clinic on Digestive Health Give today to find cancer cures for tomorrow See also Abdominal pain Can you recommend a diet after gallbladder removal? Chemo Targets Chemotherapy Chemotherapy and hair loss: What to expect during treatment Chemotherapy and sex: Is sexual activity OK during treatment? Chemotherapy nausea and vomiting: Prevention is best defense Show more Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship PolicyOpportunitiesAd Choices Mayo Clinic Store Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. NEW! – The Mayo Clinic Diet, Second Edition Relief for America's epidemic of indigestion Keeping your bones healthy and strong Manage blood pressure for better health The Mayo Clinic Diet Online

A video showing normal colonoscopy

Pioneer Plus IVUS Re-Entry Catheter plaque removal

A displaced fibular head can create tightness, pain, and even numbness or tingling along the outside of your knee and down your leg. This most often occurs after a modest hyperextension knee injury, such as landing on one leg after jumping. If you have lingering knee pain and are searching for an answer, try this move

Preventing heart attacks and stroke can involve extensive surgery to remove plaque from your arteries, but as FOX17's Nick Paranjape shows us, there's a new procedure in Middle Tennessee that is less invasive and substantially cuts down on your recovery time. At 76, Jimmy Wilkie of Hendersonville exercises on his treadmill 3-4 times a week. Recently, he started having pain in his left leg. It was so bad, he couldn't even walk. Turned out, Mr. Wilkie had a blocked artery in his leg. In years past, this would've required major bypass surgery. Not anymore!"The Turbohawk Catheter has really opened a new door for us," says Dr. Dan Wunder.Dr. Wunder, an Interventional Radiologist at Premier Radiology in Madison, is talking about the Turbohawk. It's a device which is inserted into the blocked artery, and inside the Turbohawk are 4 tiny blades."It can cut the plaque and with that shape of the disc it cuts with it pushes it forward into the catheter," says Dr. Wunder.The one-hour procedure doesn't just push the plaque to the sides where it can re-grow, but instead grabs it and removes it!"We pull it back out and it fills up," says Dr. Wunder. "Empty it out, go back down and we can cut some more out."Before and after images really say it all."They used a roto rooter as he called it," says Wilkie.A roto rooter, Turbohawk, call it what you want, but Wilkie says all he knows is the procedure worked right away!"There wasn't any pain at all in my leg," says Wilkie.It's rare, but the outpatient procedure can have complications like plaque getting pushed down in the leg. Dr. Wunder says the main symptoms of a blockage in your legs is having severe pain or cramping when you're walking or exercising.

Watch that video to know if it is safe to have sex during period

Michael La Corte MD
Ped Card

Mini-invasive surgical repair of a ruptured Achilles tendon

Most scoliosis surgeons agree that children who have very severe curves (45-50° and higher) will need surgery to lessen the curve and prevent it from getting worse. The operation for scoliosis is a spinal fusion. The basic idea is to realign and fuse together the curved vertebrae so that they heal into a single, solid bone. With the tools and technology available today, scoliosis surgeons are able to improve curves significantly.

Shoulder Injection

To facilitate the delivery of fluids during labour, obstetric anaesthetists from Coventry designed a triple IV peripheral connector with a central high-flow anti-reflux valve. This connector, now rightly known as the Coventry valve, can be used for all theatre settings and is especially useful in obstetrics, ICU, HDU and orthopaedics. More details on www.mediplus.co.uk

Laparoscopic Resection of Ovary Dermoid Cyst

Most women are put on a 3 to 5 day antibiotic. Men might be put on an antibiotic for 7 to 14 days. While symptoms usually clear up around three days after antibiotic treatment, it can take up to five days for all the bacteria in your urinary tract to die off. It may take even longer for men.

Uterine rupture is usually when the scar from your previous caesarean section tears open. Though it's uncommon, you should be aware of this risk, particularly if you're thinking about giving birth vaginally next time. It's possible for your scar to gape slightly while you're pregnant (scar dehiscence).

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Today’s video is all about peritoneal dialysis vs hemodialysis for Nursing Students and NCLEX Review.

Two common treatments for kidney failure are hemodialysis and peritoneal dialysis. With the right nursing assessments and interventions, your kidney failure patient can have a better chance at recovery.

We’re going over the roles that potassium plays in each of these two types of dialysis, as well as how stenosis monitoring can be used to prevent complications.

00:00 Introduction
01:10 Hyperkalemia in Hemodialysis
02:27 Assessing Fluid Status
03:35 Medications to Hold Before Hemodialysis
04:50 Medications Removed During Hemodialysis
05:45 Dialysis Disequilibrium Syndrome
07:20 Caring for a Fistula
09:12 Avoiding Fistula Complications
10:35 Peritoneal Dialysis
11:23 Peritonitis Risk
12:31 Respiratory Distress With Peritoneal Dialysis
13:39 Repositioning With Outflow Problems

#KidneyFailure #Dialysis #Hemodialysis #Peritonealdialysis

This video: Multiple myeloma is a cancer that forms in a type of white blood cell called a plasma cell. Plasma cells help you fight infections by making antibodies that recognize and attack germs. Multiple myeloma causes cancer cells to accumulate in the bone marrow, where they crowd out healthy blood cells. Rather than produce helpful antibodies, the cancer cells produce abnormal proteins that can cause kidney problems. Treatment for multiple myeloma isn't always necessary. If you're not experiencing signs and symptoms, you may not require treatment. If signs and symptoms develop, a number of treatments can help control your multiple myeloma.

Mastitis is an infection of the breast tissue that results in breast pain, swelling, warmth and redness. You also might have fever and chills. Mastitis most commonly affects women who are breast-feeding (lactation mastitis), although sometimes this condition can occur in women who aren't breast-feeding. In most cases, lactation mastitis occurs within the first six to 12 weeks after giving birth (postpartum), but it can happen later during breast-feeding. The condition can cause you to feel run down, making it difficult to care for your baby. Sometimes mastitis leads a mother to wean her baby before she intends to, but continuing to breast-feed, even while taking an antibiotic for the mastitis, is better for you and your baby.

After the diagnosis of primary melanoma of pectoral region had been established, the patient was referred to lymphoscintigraphy with gamma camera (techencium; nanno colloid). Two hours after the administration of the contrast medium, the operation commenced. During the operation the primary tumor wa...s excised, and the sentinel node was detected with the use of gamma probe and also excised.