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Phenylketonuria Genetics
Phenylketonuria Genetics samer kareem 1,261 Views • 3 years ago

Classical PKU is an autosomal recessive disorder, caused by mutations in both alleles of the gene for phenylalanine hydroxylase (PAH), found on chromosome 12. In the body, phenylalanine hydroxylase converts the amino acid phenylalanine to tyrosine, another amino acid.

Baby Talk from First Sounds to First Word
Baby Talk from First Sounds to First Word samer kareem 4,338 Views • 3 years ago

Developmental Milestones: Baby Talk from First Sounds to First Words

How to do an Insulin Injection
How to do an Insulin Injection samer kareem 8,901 Views • 3 years ago

Insert the needle into the rubber stopper of the insulin bottle. Push the plunger down to inject air into the bottle (this allows the insulin to be drawn more easily). Leave the needle in the bottle. Turn the bottle and syringe upside-down.

Artificial Kidney Transplant
Artificial Kidney Transplant samer kareem 6,523 Views • 3 years ago

Artificial kidney is often a synonym for hemodialysis, but may also, more generally, refer to renal replacement therapies (with exclusion of kidney transplantation) that are in use and/or in development.

Here is how minimal invasive scoliosis surgery performed.
Here is how minimal invasive scoliosis surgery performed. samer kareem 1,864 Views • 3 years ago

Scoliosis is a sideways curvature of the spine that occurs most often during the growth spurt just before puberty. While scoliosis can be caused by conditions such as cerebral palsy and muscular dystrophy, the cause of most scoliosis is unknown. Most cases of scoliosis are mild, but some children develop spine deformities that continue to get more severe as they grow. Severe scoliosis can be disabling. An especially severe spinal curve can reduce the amount of space within the chest, making it difficult for the lungs to function properly. Children who have mild scoliosis are monitored closely, usually with X-rays, to see if the curve is getting worse. In many cases, no treatment is necessary. Some children will need to wear a brace to stop the curve from worsening. Others may need surgery to keep the scoliosis from worsening and to straighten severe cases of scoliosis.

Yag Laser Trabeculoplasty for Glaucoma
Yag Laser Trabeculoplasty for Glaucoma Scott 14,786 Views • 3 years ago

Scott Geller MD of Fort Myers Florida uses A LASAG Yag laser is in thermal mode, 1.5 Joules/pulse to treat the trabecular meshwork between the cornea and iris for glaucoma. The view is of the inside anterior eyeball.

From axons to tracts
From axons to tracts Mohamed 21,086 Views • 3 years ago

The complex circuitry interconnecting different areas in the brain, known collectively as white matter, is composed of millions of axons organized into fascicles and bundles. Upon macroscopic examination of sections of the brain, it is difficult to discern the orientation of the fibers. The same is true for conventional imaging modalities. However, recent advancements in magnetic resonance imaging (MRI) make such task possible in a live subject. By sensitizing an otherwise typical MRI sequence to the diffusion of water molecules it is possible to measure their diffusion coefficient in a given direction1. Normally, the axonal membrane and myelin sheaths pose barriers to the movement of water molecules and, thus, they diffuse preferentially along the axon2. Therefore, the direction of white matter bundles can be elucidated by determining the principal diffusivity of water. The three-dimensional representation of the diffusion coefficient can be given by a tensor and its mathematical decomposition provides the direction of the tracts3; this MRI technique is known as diffusion tensor imaging (DTI). By connecting the information acquired with DTI, three-dimensional depictions of white matter fascicles are obtained4. The virtual dissection of white matter bundles is rapidly becoming a valuable tool in clinical research.

Our journey begins with a transverse section of tightly packed axons as seen through light microscopy. Although represented as a two-dimensional "slice", we see that these axons in fact resemble tubes. A simulation of water molecules diffusing randomly inside the axons demonstrates how the membranes and myelin hinder their movement across them and shows the preferred diffusion direction --along the axons. The tracts depicted through DTI slowly blend in and we ride along with them. As we zoom out even more, we realize that it is a portion of the corpus callosum connecting the two sides of the brain we were traveling on and the great difference in relative scale of the individual axons becomes evident. The surface of the brain is then shown, as well as the rest of the white matter bundles--a big, apparently chaotic tangle of wires. Finally, the skin covers the brain.

With the exception of the simulated water molecules, all the data presented in the animation is obtained through microscopy and MRI. Computer algorithms for the extraction of the cerebral structures and a custom-built graphics engine make our journey through the brain's anatomy possible in a living person.

Micrograph courtesy of Dr. Christian Beaulieu, University of Alberta.
Music by Mario Mattioli.

References:
1. Stejskal, E.O., et al., J. Chem. Phys., 1965. 42:
2. Beaulieu, C., NMR Biomed., 2002. 15:435-55.
3. Basser, P.J., et al., J. Magn. Reson. B, 1994. 103:247-54.
4. Mori, S., et al., NMR Biomed., 2002. 15:468-80.

Atrioventricular Septal Defect - AV Canal
Atrioventricular Septal Defect - AV Canal samer kareem 9,652 Views • 3 years ago

An atrioventricular septal defect (AVSD) is a heart defect in which there are holes between the chambers of the right and left sides of the heart, and the valves that control the flow of blood between these chambers may not be formed correctly. This condition is also called atrioventricular canal (AV canal) defect or endocardial cushion defect. In AVSD, blood flows where it normally should not go. The blood may also have a lower than normal amount of oxygen, and extra blood can flow to the lungs. This extra blood being pumped into the lungs forces the heart and lungs to work hard and may lead to

Bone Marrow Diseases
Bone Marrow Diseases samer kareem 4,909 Views • 3 years ago

With bone marrow disease, there are problems with the stem cells or how they develop: In leukemia, a cancer of the blood, the bone marrow makes abnormal white blood cells. In aplastic anemia, the bone marrow doesn't make red blood cells. In myeloproliferative disorders, the bone marrow makes too many white blood cells.Nov 22, 2016

Superior Rhinotomy as Anterior approach to skull base
Superior Rhinotomy as Anterior approach to skull base Doctor 114,322 Views • 3 years ago

This procedure describes one of the most versatile approaches to the anterior skull base for large tumors of the sinonasal cavity. It may be used with or without a craniofacial resection. The benefits of this approach are: wide access around the tumor; good postoperative cosmesis; & decreased operative & postoperative morbidity. We have used this approach for many bilateral tumors of the nasal & sinus cavities that approach &/or invade the skull base & brain. This video show the resection of a large esthesioneuroblastoma.

Laparoscopic Appendectomy Steps
Laparoscopic Appendectomy Steps Doctor 14,298 Views • 3 years ago

Laparoscopic Appendectomy for Acute Appendicitis Post-illeal Appendix

Laparoscopic Varicocelectomy
Laparoscopic Varicocelectomy Doctor 25,868 Views • 3 years ago

16 year Boy.Grade III Varicocele.ISV reflux on CDUS.Operative findings showed high attachment of sigmoid.This procedure was done at Pakistan Institute of Medical sciences,PIMS,Islamabad,Pakistan

wisdom teeth removal - surgery,extraction
wisdom teeth removal - surgery,extraction samer kareem 3,302 Views • 3 years ago

Simply put, there isn’t enough room for wisdom teeth because our jaws don’t grow to be big enough to have enough space for them to come in. Since there isn’t enough room for them to erupt properly, wisdom teeth tend to come in at an angle or they don’t fully emerge, which causes problems for the rest of the mouth. Third molars (the wisdom teeth) routinely damage the teeth right next door, called second molars. Dentists recommend removing wisdom teeth before they become a problem and to avoid a more complicated surgery. Read more at Ask the Dentist: https://askthedentist.com/wisdom-teeth-removal/

Laser Dental Surgery HD
Laser Dental Surgery HD Scott Stevens 6,423 Views • 3 years ago

Laser Dental Surgery HD

Vaginal Hysterectomy using Thermal Hemostasis
Vaginal Hysterectomy using Thermal Hemostasis Medical_Videos 7,862 Views • 3 years ago

Vaginal Hysterectomy using Thermal Hemostasis

AZT Mechanism of Antiviral Activity
AZT Mechanism of Antiviral Activity Medical_Videos 8,236 Views • 3 years ago

AZT Mechanism of Antiviral Activity

Anatomy of The Shoulder and Arm Muscles
Anatomy of The Shoulder and Arm Muscles Anatomy_Videos 18,400 Views • 3 years ago

Anatomy of The Shoulder and Arm Muscles

Histology of Aorta
Histology of Aorta Histology 5,912 Views • 3 years ago

Histology of Aorta

Histology of Spleen
Histology of Spleen Histology 7,194 Views • 3 years ago

Histology of Spleen

Histology of Secretory Endometrium
Histology of Secretory Endometrium Histology 4,617 Views • 3 years ago

Histology of Secretory Endometrium

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