Emphysema gradually damages the air sacs (alveoli) in your lungs, making you progressively more short of breath. Emphysema is one of several diseases known collectively as chronic obstructive pulmonary disease Smoking is the leading cause of emphysema. Your lungs' alveoli are clustered like bunches of grapes. In emphysema, the inner walls of the air sacs weaken and eventually rupture — creating one larger air space instead of many small ones. This reduces the surface area of the lungs and, in turn, the amount of oxygen that reaches your bloodstream. When you exhale, the damaged alveoli don't work properly and old air becomes trapped, leaving no room for fresh, oxygen-rich air to enter. Treatment may slow the progression of emphysema, but it can't reverse the damage.

Genetic surfactant dysfunction disorders are caused by mutations in genes encoding proteins critical for the production and function of pulmonary surfactant. These rare disorders may produce familial or sporadic lung disease, with clinical presentations ranging from neonatal respiratory failure to childhood- or adult-onset interstitial lung disease. An overview of these disorders is presented in the table.. Interstitial lung diseases in children until recently were categorized by their histologic appearance in a manner similar to that used for adult forms of interstitial lung disease (ILD). In children, the lung histopathology findings associated with desquamative interstitial pneumonitis (DIP) are now known to often result from genetic mechanisms that disrupt normal surfactant production and metabolism. By contrast, DIP in adults is considered to represent a distinct type of ILD, which is strongly associated with cigarette smoking and carries a relatively favorable prognosis [1]. These genetic disorders also result in histopathologic patterns other than DIP, including findings of pulmonary alveolar proteinosis and chronic pneumonitis of infancy. An understanding of the pathogenesis of these disorders permits a mechanistic classification as genetic surfactant dysfunction disorders instead of their previous classification based upon histologic appearance.

This video describes, step by step, how to place an external ventricular drain. This is a common neurosurgical procedure used to relieve intracranial pressure.

This video demonstrates how a broken nose is fixed using only local anesthesia and without sedation. Of course, this can also be performed while asleep.

Human Circulatory System and heart video

A displaced fibular head can create tightness, pain, and even numbness or tingling along the outside of your knee and down your leg. This most often occurs after a modest hyperextension knee injury, such as landing on one leg after jumping. If you have lingering knee pain and are searching for an answer, try this move

In these times when there are uncountable online pharmacies being recognized, mynetpharma.com stands out as one of the best.The drug catalogue of this web pharmacy has medicines to treat a range of health issues ranging from medicines to treat obesity, alopecia, allergy, bacterial infections, pain etc. Mynetpharma(http://www.mynetpharma.com) provide a range of top quality medicines to their customers who are based in different parts of the world to help them overcome their health problems.

The preferred route of access for temporary transvenous pacing is the internal jugular vein followed by subclavian and femoral veins. However, all the major venous access sites (internal and external jugular, subclavian, brachial, femoral) have been used and each is associated with particular problems.

Fremale to male gender reassignment surgery

By 5 weeks' gestational age, the wolffian (ie, mesonephric) and the müllerian (ie, paramesonephric) ducts have formed from intermediate mesoderm. In the absence of testosterone and müllerian inhibitory substance, the mesonephric ducts regress and the paramesonephric ducts continue to form the female reproductive structures with fusion of the distal portions of the paramesonephric ducts to give rise to the uterine fundus, the cervix, and the upper vagina. These developmental changes are genetically controlled in large part by a series of complex transcriptional signaling pathways including Wnt signaling, Hox genes, and many others. In a female fetus, the wolffian duct disappears except for nonfunctional vestiges. The müllerian duct is lined by a columnar epithelium. This includes the entire cervix and upper vagina to the vaginal plate (ie, sinovaginal bulb). Through a process of squamous metaplasia, the vagina and a variable portion of the ectocervix become covered with squamous epithelium. This process is complete by the fifth month of pregnancy.

Peritoneal dialysis (per-ih-toe-NEE-ul die-AL-uh-sis) is a way to remove waste products from your blood when your kidneys can no longer do the job adequately. A cleansing fluid flows through a tube (catheter) into part of your abdomen and filters waste products from your blood. After a prescribed period of time, the fluid with filtered waste products flows out of your abdomen and is discarded. Peritoneal dialysis differs from hemodialysis, a more commonly used blood-filtering procedure. With peritoneal dialysis, you can give yourself treatments at home, at work or while traveling. Peritoneal dialysis isn't an option for everyone wit

Watch that video to know the Causes of Pain During Intercourse

Pyogenic liver abscess Email this page to a friend Email this page to a friend Facebook Twitter Google+ Pyogenic liver abscess is a pus-filled area in the liver. Causes There are many potential causes of liver abscesses, including: Abdominal infection, such as appendicitis, diverticulitis, or a perforated bowel Infection in the blood Infection of the bile draining tubes Recent endoscopy of the bile draining tubes Trauma that damages the liver The most common bacteria that cause liver abscesses are: Escherichia coli Bacteroides Enterococcus Klebsiella pneumoniae Staphylococcus aureus Streptococcus In most cases, more than one type of bacteria is found.

ROBOTIC ASSISTED RADICAL NEPHRECTOMY

Can a Vaccine Give Me the Disease It’s Supposed to Protect Me Against?

How to pull a wisdom tooth fully impacted

Note: This video contains graphic surgical footage so viewer discretion is advised.

Director of the Penn Orthopaedics Robotics and Navigation Program, Dr. Christopher Travers, discusses robotic joint replacement surgery, which is one of the multiple options that Penn Orthopaedics offers for joint replacement surgery. He walks through a robotic knee replacement surgery, discussing what the procedure is, how it differs from traditional joint replacement surgery, and the benefits.

Refer a patient (physicians only):
https://www.pennmedicine.org/refer-your-patient

Learn more about the Penn Joint Replacement Program:
https://www.pennmedicine.org/f....or-patients-and-visi

Learn more about Dr. Travers:
https://www.pennmedicine.org/providers/profile/christopher-travers?fadf=pennmedicine&keyword=travers

#RoboticSurgery #JointReplacementSurgery #KneeReplacement #SurgicalFootage

Inner Workings tells the story of the ceaseless pull of the human heart — even as it works against the very stoic realism of the brain.

Watch that video to know if it is safe to have sex during period

The rotator cuff is a group of muscles and tendons that surround the shoulder joint, keeping the head of your upper arm bone firmly within the shallow socket of the shoulder. A rotator cuff injury can cause a dull ache in the shoulder, which often worsens when you try to sleep on the involved side. Rotator cuff injuries occur most often in people who repeatedly perform overhead motions in their jobs or sports. Examples include painters, carpenters, and people who play baseball or tennis. The risk of rotator cuff injury also increases with age. Many people recover from rotator cuff disease with physical therapy exercises that improve flexibility and strength of the muscles surrounding the shoulder joint. Sometimes, rotator cuff tears may occur as a result of a single injury. In those circumstances, medical care should be provided as soon as possible. Extensive rotator cuff tears may require surgical repair, transfer of alternative tendons or joint replacement.