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Benzodiazepines are a class of agents that work on the central nervous system, acting selectively on gamma-aminobutyric acid-A (GABA-A) receptors in the brain. GABA is a neurotransmitter that inhibits or reduces the activity of nerve cells (neurons) within the brain. Benzodiazepines open GABA-activated chloride channels, and allow chloride ions to enter the neuron. This makes the neuron negatively charged and resistant to excitation.
A decade ago we thought that Chikungunya was a tropical disease restricted to the rain forests. However, after the 2007 epidemic in Italy and later in the Reunion islands, this dreaded condition has now spread to the Carribean and the Americas. Its an arthropod borne alpha virus which causes fever, polyarthralgia and arthritis. There could be serious complications in the adult such as meningoencephalitis or GBS as well as in neonates. This presentation discusses in detail the clinical features, diagnosis and management of Chikungunya fever. A detailed discussion of its complications is also included. Check out our other videos
Pectus excavatum repair is surgery to correct pectus excavatum. This is a congenital (present at birth) deformity of the front of the chest wall that causes a sunken breastbone (sternum) and ribs. Pectus excavatum is also called funnel or sunken chest. It may worsen during the teen years.
A brief description of the pathophysiology, clinical features, warning signs, diagnosis and management of Dengue fever. This description is based on the World Health Organisation guidelines of the management of Dengue fever.
The discussion begins with a basic explanation of Bone biology taking into consideration the osteoblast and osteoclast balance. Concepts of RANK, RANK ligand and Osteoprotegerin are included. Risk factors for Osteoporosis such as Age, alcohol, smoking, sedentary lifestyle are also discussed.
The "great arteries" in this anomaly refer to the aorta and the pulmonary artery, the two major arteries carrying blood away from the heart. In cases of transposition of the great arteries, these vessels arise from the wrong ventricle. They are "transposed" from their normal position so that the aorta arises from the right ventricle and the pulmonary artery from the left ventricle. Other heart defects may occur along with transposition of the great arteries. About 25 percent of children with transposition will also have a ventricular septal defect (VSD) . In nearly a third, the branching pattern of the coronary arteries as they leave the transposed aorta is unusual. Infants may also have narrowing below the pulmonary valve that blocks blood flow from the left ventricle to the lungs.
Cigarette contain tobacco that is very harmful but vaporizers does not contain tobacco. ... The most basic difference between vaping and cigarette usage is that cigarettes require combustion. You need fire to light a cigarette. On the other hand, vaping requires electricity and creates vapor.
This cyst had been slowly growing for decades and created some redundant skin on the surface. A decision was made to make a slightly bigger incision in order to remove this tissue as well. As a result of this deeper process, 2 deep dermal sutures were added before the superficial interrupted sutures were put in place.
How do you know if you have an STD? There’s only one way — you have to get tested. How do they test for STDs? Here’s the good news: STD testing is usually quick and painless. Get answers to all your questions about how to get tested for STDs.
Emergency Contraception is a way to prevent pregnancy AFTER unprotected sex. Lots of people have questions about it: What does the morning after pill do? How does emergency contraception work to prevent pregnancy? What are the different types of emergency contraception? This video answers these questions and more.
Fibrodysplasia ossificans progressiva (FOP) is a disorder in which muscle tissue and connective tissue such as tendons and ligaments are gradually replaced by bone (ossified), forming bone outside the skeleton (extra-skeletal or heterotopic bone) that constrains movement. This process generally becomes noticeable in early childhood, starting with the neck and shoulders and proceeding down the body and into the limbs. Extra-skeletal bone formation causes progressive loss of mobility as the joints become affected. Inability to fully open the mouth may cause difficulty in speaking and eating. Over time, people with this disorder may experience malnutrition due to their eating problems. They may also have breathing difficulties as a result of extra bone formation around the rib cage that restricts expansion of the lungs.