Eosinophilic granulomatosis with polyangiitis (EGPA)—or, as it was traditionally termed, Churg-Strauss syndrome—is a rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels and is associated with severe asthma and blood and tissue eosinophilia. [1] Like granulomatosis with polyangiitis (Wegener granulomatosis), and the microscopic form of periarteritis (ie, microscopic polyangiitis), EGPA is an antineutrophil cytoplasmic antibody (ANCA)–associated vasculitide. [2, 3, 4, 5] In 1951, Churg and Strauss first described the syndrome in 13 patients who had asthma, eosinophilia, granulomatous inflammation, necrotizing systemic vasculitis, and necrotizing glomerulonephritis. [3] In 1990, the American College of Rheumatology (ACR) proposed the following six criteria for the diagnosis of Churg-Strauss syndrome [6] : Asthma (wheezing, expiratory rhonchi) Eosinophilia of more than 10% in peripheral blood Paranasal sinusitis Pulmonary infiltrates (may be transient) Histological proof of vasculitis with extravascular eosinophils Mononeuritis multiplex or polyneuropathy

A rotator cuff tear is a common injury, especially in sports like baseball or tennis, or in jobs like painting or cleaning windows. It usually happens over time from normal wear and tear, or if you repeat the same arm motion over and over. But it also can happen suddenly if you fall on your arm or lift something heavy. Your rotator cuff is a group of four muscles and tendons that stabilize your shoulder joint and let you lift and rotate your arms. There are two kinds of rotator cuff tears. A partial tear is when the tendon that protects the top of your shoulder is frayed or damaged. The other is a complete tear. That’s one that goes all the way through the tendon or pulls the tendon off the bone.

A leaking mitral valve allows blood to flow in two directions during the contraction. Some blood flows from the ventricle through the aortic valve – as it should – and some blood flows back into the atrium. A leaking (or regurgitant) aortic valve allows blood to flow in two directions. Oxygen-rich blood either flows out through the aorta to the body – as it should – or it flows backwards from the aorta into the left ventricle when the ventricle relaxes. Leaking valves can cause the heart to work harder to pump the same amount of blood.

Demonstration of Burke-Baier wound closure forceps on simulated wound near eyebrow.

9 Months In The Womb: A Remarkable Look At Fetal Development Through Ultrasound

Start out with a visit to a doctor called a urologist. He'll give you a physical exam and ask you questions about your lifestyle and medical history, such as: Surgeries you've had Medications you take Your exercise habits Whether you smoke or take recreational drugs He may also have a frank discussion with you about your sex life, including any problems you've had or whether you have or ever had any STDs (sexually transmitted diseases). You'll probably be asked to give a sample of semen for analysis.

When the hematocrit rises to 60 or 70%, which it often does in polycythemia, the blood viscosity can become as great as 10 times that of water, and its flow through blood vessels is greatly retarded because of increased resistance to flow. This will lead to decreased oxygen delivery.

www.lung.org > Lung Health and Diseases > Lung Disease Lookup > Silicosis Learn About Silicosis Silicosis is a lung disease caused by breathing in tiny bits of silica, a mineral that is part of sand, rock, and mineral ores such as quartz. It mostly affects workers exposed to silica dust in occupations such mining, glass manufacturing, and foundry work. Over time, exposure to silica particles causes scarring in the lungs, which can harm your ability to breathe. Key Facts There are three types of silicosis: acute, chronic, and accelerated. It occurs in workers from mines, foundries, sandblasting, and glass manufacturing. About 2 million US workers remain potentially exposed to occupational silica. There is no cure for silicosis, but it can be prevented. What Is Silicosis? There are three types of silicosis: Acute silicosis, which causes cough, weight loss, and fatigue within a few weeks or years of exposure to inhaled silica. Chronic silicosis, which appears 10 to 30 years after exposure and can affect upper lungs and sometimes cause extensive scarring. Accelerated silicosis, which occurs within 10 years of high-level exposure. Silicosis can develop within a few weeks to even decades after exposure. When people breathe silica dust, they inhale tiny particles of the mineral silica. This silica dust can cause fluid buildup and scar tissue in the lungs that cuts down your ability to breathe. This can lead to lung scarring and cough, weight loss, and fatigue.

In a normal person, when a muscle tendon is tapped briskly, the muscle immediately contracts due to a two-neuron reflex arc involving the spinal or brainstem segment that innervates the muscle. The afferent neuron whose cell body lies in a dorsal root ganglion innervates the muscle or Golgi tendon organ associated with the muscles; the efferent neuron is an alpha motoneuron in the anterior horn of the cord. The cerebral cortex and a number of brainstem nuclei exert influence over the sensory input of the muscle spindles by means of the gamma motoneurons that are located in the anterior horn; these neurons supply a set of muscle fibers that control the length of the muscle spindle itself.

Sacrococcygeal teratoma (SCT) is an unusual tumor that, in the newborn, is located at the base of the tailbone (coccyx). This birth defect is more common in female than in male babies. Although the tumors can grow very large, they are usually not malignant (that is, cancerous).

A filling is a way to restore a tooth damaged by decay back to its normal function and shape. When a dentist gives you a filling, he or she first removes the decayed tooth material, cleans the affected area, and then fills the cleaned out cavity with a filling material. By closing off spaces where bacteria can enter, a filling also helps prevent further decay. Materials used for fillings include gold, porcelain, a composite resin (tooth-colored fillings), and an amalgam (an alloy of mercury, silver, copper, tin and sometimes zinc).

First Head Transplant Surgery

In Deep Vein Thrombosis, blood clot is able to reach the heart and from there it transport to the arteries of the lungs, where it may stuck in the...

This system treats type 2 diabetes by promoting weight loss.

This surgical procedure helps children defeat bone cancer.

A short story about Warts, Are they contagious?

The cyst was technically 46.5 pounds and her doctors call it the largest in world history. I am not sure if that is true, but it is a massive cyst

Terrifying Sinus Infection - Disturbing - Must Watch

Most retinal tears need to be treated by sealing the retina to the back wall of the eye with laser surgery or cryotherapy (a freezing treatment). Both of these procedures create a scar that helps seal the retina to the back of the eye. This prevents fluid from traveling through the tear and under the retina, which usually prevents the retina from detaching. These treatments cause little or no discomfort and may be performed in your ophthalmologist’s office. With laser surgery, your ophthalmologist uses a laser to make small burns around the retinal tear. The scarring that results seals the retina to the underlying tissue, helping to prevent a retinal detachment.

Traumatic Brain Injury (TBI) TBI is defined as an alteration in brain function, or other evidence of brain pathology, caused by an external force. Adopted by the Brain Injury Association Board of Directors in 2011. This definition is not intended as an exclusive statement of the population served by the Brain Injury Association of America. Acquired Brain Injury An acquired brain injury is an injury to the brain, which is not hereditary, congenital, degenerative, or induced by birth trauma. An acquired brain injury is an injury to the brain that has occurred after birth. There is sometimes confusion about what is considered an acquired brain injury. By definition, any traumatic brain injury (e.g. from a motor vehicle accident or assault) could be considered an acquired brain injury. In the field of brain injury, acquired brain injuries are typically considered any injury that is non traumatic. Examples of acquired brain injury include stroke, near drowning, hypoxic or anoxic brain injury, tumor, neurotoxins, electric shock or lightning strike.