Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic liver disease resulting from progressive destruction of the bile ducts in the liver – called the intrahepatic bile ducts. Bile produced in your liver travels via these ducts to your small intestine where it aids in the digestion of fat and fat-soluble vitamins (A, D, E and K). When the ducts are destroyed, bile builds up in the liver contributing to inflammation and scarring (fibrosis). Eventually this can lead to cirrhosis and its associated complications, as scar tissue replaces healthy liver tissue and liver function becomes increasingly impaired.

Vascular dementia is a general term describing problems with reasoning, planning, judgment, memory and other thought processes caused by brain damage from impaired blood flow to your brain. You can develop vascular dementia after a stroke blocks an artery in your brain, but strokes don't always cause vascular dementia. Whether a stroke affects your thinking and reasoning depends on your stroke's severity and location. Vascular dementia also can result from other conditions that damage blood vessels and reduce circulation, depriving your brain of vital oxygen and nutrients

Lupus Treatment | Causes Of Lupus Flares

Norepinephrine is synthesized from dopamine by dopamine β-hydroxylase.[7] It is released from the adrenal medulla into the blood as a hormone, and is also a neurotransmitter in the central nervous system and sympathetic nervous system where it is released from noradrenergic neurons.

Eosinophilic granulomatosis with polyangiitis (EGPA)—or, as it was traditionally termed, Churg-Strauss syndrome—is a rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels and is associated with severe asthma and blood and tissue eosinophilia. [1] Like granulomatosis with polyangiitis (Wegener granulomatosis), and the microscopic form of periarteritis (ie, microscopic polyangiitis), EGPA is an antineutrophil cytoplasmic antibody (ANCA)–associated vasculitide. [2, 3, 4, 5] In 1951, Churg and Strauss first described the syndrome in 13 patients who had asthma, eosinophilia, granulomatous inflammation, necrotizing systemic vasculitis, and necrotizing glomerulonephritis. [3] In 1990, the American College of Rheumatology (ACR) proposed the following six criteria for the diagnosis of Churg-Strauss syndrome [6] : Asthma (wheezing, expiratory rhonchi) Eosinophilia of more than 10% in peripheral blood Paranasal sinusitis Pulmonary infiltrates (may be transient) Histological proof of vasculitis with extravascular eosinophils Mononeuritis multiplex or polyneuropathy

A cervical herniated disc may be treated by removing part of the disc through a small incision (microdiscectomy). If this is done from the back (posteriorly) rather than from the front of the neck, a spinal fusion is not necessary. The alternative is an anterior cervical discectomy and fusion procedure.

Compartment syndrome can develop in the foot following crush injury or closed fracture. Following some critical threshold of bleeding and/or swelling into the fixed space compartments, arterial pulse pressure is insufficient to overcome the osmotic tissue pressure gradient, leading to cell death. The complicating factor is related to the magnitude of the force of the crush injury. The amount of swelling or bleeding has to be sufficient to impair arterial inflow, while not being of sufficient magnitude to produce an open injury, which decompresses the pressure within the affected compartments. When the injury is open, we then attribute the late disability primarily to the crushing injury to the involved muscles.

Demonstration of Burke-Baier wound closure forceps on simulated wound near eyebrow.

In a normal person, when a muscle tendon is tapped briskly, the muscle immediately contracts due to a two-neuron reflex arc involving the spinal or brainstem segment that innervates the muscle. The afferent neuron whose cell body lies in a dorsal root ganglion innervates the muscle or Golgi tendon organ associated with the muscles; the efferent neuron is an alpha motoneuron in the anterior horn of the cord. The cerebral cortex and a number of brainstem nuclei exert influence over the sensory input of the muscle spindles by means of the gamma motoneurons that are located in the anterior horn; these neurons supply a set of muscle fibers that control the length of the muscle spindle itself.

Tooth colored composite fillings are chemically bonded to teeth. For this reason, the placement of white fillings does not always require numbing the area being restored. Numbing (anesthetizing) the area is often required if tooth decay has progressed beneath the enamel layer and into the underlying dentin layer which surrounds the nerve of the tooth. Once decay is removed, the tooth is cleaned and a primer (weak acid) is applied to the area being restored. The primer opens pores in the enamel and dentin. A bonding agent is then flowed into the open pores and cured. Curing prepares the bonding agent to adhere to the tooth colored filling material. The filling material is then placed inside the tooth. After shaping the tooth colored filling material to resemble the natural anatomy of your tooth it is hardened by curing with a strong curing light. Once the white filling hardens, your bite will be checked to make sure your teeth fit together properly. If the tooth filling extends into the space between your teeth your dentist will also make sure you can floss between your teeth properly. Adjustments will be made if necessary followed by smoothing and polishing of your new filling..

This coating prevents blood from sticking on medical devices

Bronchoscopy Procedure - See inside the lungs!

Always Love Your Mother Because You Will Never Get Another

Surgery involves removing the cyst as well as part of the involved joint capsule or tendon sheath, which is considered the root of the ganglion. Even after excision, there is a small chance the ganglion will return. A ganglion cyst at the wrist is removed during a surgical procedure called excision.

Future Baby

Frostbite is an injury caused by freezing of the skin and underlying tissues. First your skin becomes very cold and red, then numb, hard and pale. Frostbite is most common on the fingers, toes, nose, ears, cheeks and chin. Exposed skin in cold, windy weather is most vulnerable to frostbite. But frostbite can occur on skin covered by gloves or other clothing. Frostnip, the first stage of frostbite, doesn't cause permanent skin damage. You can treat very mild frostbite with first-aid measures, including rewarming your skin. All other frostbite requires medical attention because it can damage skin, tissues, muscle and bones. Possible complications of severe frostbite include infection and nerve damage.

In breastfeeding, the latch is the moment everything comes together: Your baby takes a big mouthful of your nipple and areola (or "latches on"), begins to suck, and draws out your milk. When your baby has established a good latch, your nipple soreness is minimized and your little one gets the nourishment he needs. How do you pull all that off? First and most important, have faith in yourself and your baby. "Babies are designed to breastfeed," says Emily Pease, R.N., international board certified lactation consultant (IBCLC), of Swedish Hospital's Breastfeeding Center in Seattle. "They are born with instincts that help them find Mom's breast and latch on often with very little assistance. And if problems do come up, there are lots of ways to troubleshoot." Here are more steps to get a good latch right from the start.

The biceps muscle is located in the front of your upper arm. It is attached to the bones of the shoulder and elbow by tendons — strong cords of fibrous tissue that attach muscles to bones. Tears of the biceps tendon at the elbow are uncommon. They are most often caused by a sudden injury and tend to result in greater arm weakness than injuries to the biceps tendon at the shoulder. Once torn, the biceps tendon at the elbow will not grow back to the bone and heal. Other arm muscles make it possible to bend the elbow fairly well without the biceps tendon. However, they cannot fulfill all the functions of the elbow, especially the motion of rotating the forearm from palm down to palm up. This motion is called supination. To return arm strength to near normal levels, surgery to repair the torn tendon is usually recommended. However, nonsurgical treatment is a reasonable option for patients who may not require full arm function.

When anxiety takes hold, these steps can help you regain control.

Supraventricular tachycardia (SVT) is an abnormal condition of heart which increases normal heartbeat rate rapidly. Normally, heartbeat rate should be between 80 to 100 beats per minute. For more info: https://goo.gl/14btbU