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Basics of Multiple Endocrine Neoplasia
Basics of Multiple Endocrine Neoplasia samer kareem 5,094 Views • 2 years ago

Multiple endocrine neoplasia is a group of disorders that affect the body's network of hormone-producing glands (the endocrine system). Hormones are chemical messengers that travel through the bloodstream and regulate the function of cells and tissues throughout the body. Multiple endocrine neoplasia typically involves tumors (neoplasia) in at least two endocrine glands; tumors can also develop in other organs and tissues. These growths can be noncancerous (benign) or cancerous (malignant). If the tumors become cancerous, the condition can be life-threatening.

Cortisol and Glucocorticoids
Cortisol and Glucocorticoids samer kareem 3,644 Views • 2 years ago

The vast majority of glucocorticoid activity in most mammals is from cortisol, also known as hydrocortisone. Corticosterone, the major glucocorticoid in rodents, is another glucocorticoid. Cortisol binds to the glucocorticoid receptor in the cytoplasm and the hormone-receptor complex is then translocated into the nucleus, where it binds to its DNA response element and modulates transcription from a battery of genes, leading to changes in the cell's phenotype. Only about 10% of circulating cortisol is free. The remaining majority circulates bound to plasma proteins, particularly corticosteroid-binding globulin (transcortin). This protein binding likely decreases the metabolic clearance rate of glucocorticoids and, because the bound steroid is not biologically active, tends to act as a buffer and blunt wild fluctuations in cortisol concentration.

Serious Side Effects of Using Steroids
Serious Side Effects of Using Steroids hooda 57,782 Views • 2 years ago

Watch that video to know the Serious Side Effects of Using Steroids

Cataplexy
Cataplexy samer kareem 5,608 Views • 2 years ago

Cataplexy is a sudden, temporary loss of muscle tone that can result in collapse. It is often caused by intense emotions, including laughter

Atrial fibrillation vs Atrial Flutter
Atrial fibrillation vs Atrial Flutter samer kareem 61,446 Views • 2 years ago

Atrial fibrillation vs Atrial Flutter

Hemorrhoids Surgical Repairing Operation
Hemorrhoids Surgical Repairing Operation hooda 48,329 Views • 2 years ago

Watch that Hemorrhoids Surgical Repairing Medical Operation

Testing Urine for Protein and Glucose by Dip Stick
Testing Urine for Protein and Glucose by Dip Stick Scott 12,373 Views • 2 years ago

This video demonstrates how use a commercially-prepared "dip-stick" to test a random urine specimen for the presence of protein or glucose.

 Testing for Occult Blood in the Stool
Testing for Occult Blood in the Stool Scott 11,426 Views • 2 years ago

This video demonstrates how to test for trace amounts of blood in the patients stool. Trace amounts of blood in the stool can be sign of a number of problems, colon cancer being the most worrisome.

Acanthamoeba Keratitis
Acanthamoeba Keratitis samer kareem 8,145 Views • 2 years ago

Acanthamoeba keratitis is a rare disease in which amoebae invade the cornea of the eye. It may result in permanent visual impairment or blindness.

Sucking Reflex
Sucking Reflex Medical_Videos 7,452 Views • 2 years ago

Sucking Reflex

Ten common mistakes in treating lupus nephritis:
Ten common mistakes in treating lupus nephritis: samer kareem 3,649 Views • 2 years ago

Anatomy of The Superficial Face
Anatomy of The Superficial Face Anatomy_Videos 29,804 Views • 2 years ago

Anatomy of The Superficial Face

Histology of Bone Marrow Smear
Histology of Bone Marrow Smear Histology 8,830 Views • 2 years ago

Histology of Bone Marrow Smear

Bowel Surgery for IBD
Bowel Surgery for IBD samer kareem 3,747 Views • 2 years ago

This animation describes surgery for patients with inflammatory bowel disease (IBD) -- IPAA, removal of colon, intestinal resection, & stricturoplasty.

Wound-closure technologies
Wound-closure technologies samer kareem 11,763 Views • 2 years ago

Wound-closure technologies are becoming less painful and more efficient at closing wounds

Ganglion Cyst  at Wrist
Ganglion Cyst at Wrist samer kareem 13,980 Views • 2 years ago

Ganglion cysts are the most common mass or lump in the hand. They are not cancerous and, in most cases, are harmless. They occur in various locations, but most frequently develop on the back of the wrist. These fluid-filled cysts can quickly appear, disappear, and change size.

Popping a Massive Dental Abscess
Popping a Massive Dental Abscess Mohamed Ibrahim 5,569 Views • 2 years ago

Surgical drainage of dental abscess extending Into the Sub mandibular Space

Wilson Disease
Wilson Disease samer kareem 10,103 Views • 2 years ago

Wilson's disease is a rare inherited disorder that causes too much copper to accumulate in your liver, brain and other vital organs. Symptoms typically begin between the ages of 12 and 23. Copper plays a key role in the development of healthy nerves, bones, collagen and the skin pigment melanin. Normally, copper is absorbed from your food, and any excess is excreted through bile — a substance produced in your liver.

Euthyroid sick syndrom
Euthyroid sick syndrom samer kareem 5,732 Views • 2 years ago

Euthyroid sick syndrome (ESS), sick euthyroid syndrome (SES), thyroid allostasis in critical illness, tumours, uremia and starvation (TACITUS), non-thyroidal illness syndrome (NTIS) or low T3 low T4 syndrome is a state of adaptation or dysregulation of thyrotropic feedback control where the levels of T3 and/or T4 are ...

Low Thyroid - Could It Be A T3 Problem?
Low Thyroid - Could It Be A T3 Problem? samer kareem 5,793 Views • 2 years ago

NTIS refers to a syndrome found in seriously ill or starving patients with low fT3, usually elevated RT3, normal or low TSH, and if prolonged, low fT4. It is found in a high proportion of patients in the ICU setting, and correlates with a poor prognosis if TT4 is <4ug/dl. The patho-physiology includes suppression of TRH release, reducedT3 and T4 turnover, reduction in liver generation of T3, increased formation of RT3, and tissue specific down-regulation of deiodinases, transporters, and TH receptors. Although long debated, tissue TH levels are definitely reduced, and tissue hypothyroidism is presumably present. This is often not clinically evident because of the brief duration, and reduced but not absent tissue levels of TH. Although recognized for nearly 4 decades, interpretation of the syndrome is contested, because of lack of data. Some observes, totally without data, argue that it is a protective response and should not be treated. Other observers (as in this review) present available data suggesting, but not proving, that thyroid hormone replacement is appropriate, not harmful, and may be beneficial. The best form of treatment (TRH,TSH,or T3+T4) and possible accompanying treatments (GHRH, Cortisol, nutrition, insulin) lack consensus. In this review current data are laid out for reader’s review and judgment.

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