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Normal Skin Histology - Explained by a Dermatopathologist
Normal Skin Histology - Explained by a Dermatopathologist DrPhil 99 Views • 2 years ago

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology)

Topics discussed:

Epidermis:
Layers of epidermis: 0:10
Melanocytes vs Keratinocytes: 5:16
Langerhans cells: 10:10 & 33:30 & 57:30

Dermis:
Papillary and reticular dermis: 11:50
Three types of white empty spaces on a slide: vessels, glands/ducts/cysts, or artifact: 15:25
Blood vessels & nerves: 18:24 & 48:50 & 58:59
Arrector pili & other dermal smooth muscle: 20:00

Adnexal:
Sebaceous gland: 21:10
Hair follicle 23:14
Eccrine sweat glands and ducts 24:45 & 50:00
Gland/duct vs blood vessel 27:20 & 48:50
Apocrine glands: this video https://kikoxp.com/posts/7837 (at 12:30)
Acrosyringium: this video https://kikoxp.com/posts/7837 (at 10:00)

Three types of pink bundles: smooth muscle, nerve, dense connective tissue: 27:50

Acral skin (palm sole) with contact dermatitis 29:37
Parakeratosis 30:00
Perivascular lymphocytes 30:40
Eosinophils vs neutrophils 31:20
Spongiosis with desmosome keratinocyte spines 32:10
Spongiotic vesicles with Langerhans cells 33:30
Normal acral skin (palm & sole) with stratum lucidum 34:20
Normal glomus body/apparatus (canal of Sucquet-Hoyer) 35:40
Nerve 36:46 & 51:50
Adipose tissue (white fat cells) in subcutis with Lochkern 37:55
Normal scalp skin with large anagen hair follicles: 39:30
Hair follicle anatomy (bulb/matrix, inner root sheath, outer root sheath, hair shaft, isthmus, infundibulum): 40:55 (labeled images):
https://kikoxp.com/posts/3661 & https://kikoxp.com/posts/7899
Pacinian corpuscle 50:40
Meissner corpuscle 1:02:28

Dense regular connective tissue (Fascia/Tendon/Ligament) vs Smooth Muscle 53:00

Basic Normal Skin Immunohistochemistry:
-cytokeratin in epidermis: 55:33
-S100 in melanocytes and Langerhans cells and adipocytes: 57:30
-Desmin in smooth muscle (arrector pili and blood vessels): 58:59
-CD31 in endothelial cells of blood vessels: 59:33
-SOX-10 in melanocytes: 1:00:40

Digit/Finger/Toe histology (amputation for subungual acral melanoma) 1:04:10 & 1:08:30
-bone 1:05:40
-glomus body 1:05:15
-tendon/ligament 1:06:10
-artery 1:06:58
-fingernail/toenail 1:08:54
-acrosyringium 1:10:45

Solar elastosis (what wrinkles look like microscopically!) 1:11:50

Other videos you might like:
Tendon vs Nerve Histology Made Simple with the Ramen Noodle Sign (of Fulton) video: https://kikoxp.com/posts/4466
Melanocytes vs Keratinocytes made easy video: https://kikoxp.com/posts/3802
Blood Vessel vs Gland vs Artifact Made Easy video: https://kikoxp.com/posts/4808

The basic normal structures of the skin discussed and described by a dermatopathologist. This material is intended for use by medical students, junior pathology or dermatology residents, or for anyone else studying normal human histology. Special thanks to two of my medical students at UAMS for helping make this video possible. Miki Lindsey convinced me that I really needed to sit down and record this video. Akash Patel took time to edit the video and make it ready for YouTube. My sincere thanks to both of them for helping me overcome procrastination.

Huge thanks to Abigail Cline, a medical student at Medical College of Georgia, for volunteering to type a transcript of this ENTIRE video (over 14,000 words!) so that I could provide closed caption subtitles for those with hearing impairments and for those who may need assistance in understanding spoken English (particularly given how quickly I speak!). You can access a text version of her transcript of my video here: https://kikoxp.com/posts/5390

Correction - I made a mistake in the video. I said that sebaceous gland secretions are turned into smelly substances by bacteria and that this makes body odor. That is incorrect. That is actually true of APOCRINE gland secretions not sebaceous secretions.

Also, in the past I used "keratinocyte" and "squamous cell" interchangeably (this is because in dermatopathology, we see and talk about squamous cell carcinomas all the time, and those tumors are composed of keratinocytes). But technically, in normal skin histology, "squamous cell" refers only to the flattened keratinocytes in the superficial epidermis. Thankfully, a histology PhD colleague pointed this out to me and corrected my lazy nomenclature!

Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB

This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.

Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.

Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Facebook: https://www.facebook.com/JMGardnerMD/

Robotic Surgery for Pelvic Organ Prolapse
Robotic Surgery for Pelvic Organ Prolapse samer kareem 5,843 Views • 2 years ago

B - 12 shot
B - 12 shot yu696969 50,492 Views • 2 years ago

Injection in buttocks

Examination of Inguinal Hernia,Direct Inguinal Hernia,Indirect Inguinal Hernia, Inguinal Lymph Nodes
Examination of Inguinal Hernia,Direct Inguinal Hernia,Indirect Inguinal Hernia, Inguinal Lymph Nodes DrPhil 203 Views • 2 years ago

#final #fumc #mbbs #medicalstudents #mbbsabroad #doctor #fcps #fcpspart #surgeryeducation #surgeryreview #trainee #exampreparation

Kootenai Health - Open Heart Surgery
Kootenai Health - Open Heart Surgery Surgeon 115 Views • 2 years ago

Kootenai Health provides open heart surgery complete with specially trained cardiothoracic surgeons and operating room teams. Programs include pre-operative appointments and cardio rehabilitation to speed recovery.

Breast Examination
Breast Examination Doctor 56,008 Views • 2 years ago

A new video illustrating the horizontal breast exam technique whihc is performed by doctors for any breast masses or abnormalities.

Surgery: Manual Small Incision Cataract Surgery using Blumenthal Technique
Surgery: Manual Small Incision Cataract Surgery using Blumenthal Technique Surgeon 182 Views • 2 years ago

This video demonstrates a manual small incision cataract surgery using a Blumenthal technique, in a white cataract.

Surgeon: Dr. Rishi Swarup, FRCS, Medical Director & Senior Consultant, Swarup Eye Centre, India

abdomen physical examination
abdomen physical examination M_Nabil 163,702 Views • 2 years ago

a video of abdominal physical examination including all the required items:
-Inspection
-Palpation
-Percussion
-Auscultation

What is the Whipple Procedure - Mayo Clinic
What is the Whipple Procedure - Mayo Clinic Surgeon 211 Views • 2 years ago

Dr. Horacio Asbun, Mayo Clinic in Florida, explains the Whipple procedure using this animated graphic of a pancreas. Cancer of the pancreas affects 45,000 people every year in the U.S., and it is the fourth leading cause of cancer-related deaths. The five-year overall survival rate if a tumor is detected early and surgically removed is 22 percent, versus 6 percent without early detection and surgery. To learn more, visit http://mayocl.in/2zk7FDi.

This video in Spanish/español: https://www.youtube.com/watch?v=N_zWboNMKWk

Testicular Cancer Self Exam
Testicular Cancer Self Exam Surgeon 69,691 Views • 2 years ago

screening and early detection is the key to beating any form of cancer. share this with a friend. you may save a life.

Basic histological staining methods (preview)  - Human Histology | Kenhub
Basic histological staining methods (preview) - Human Histology | Kenhub DrPhil 92 Views • 2 years ago

In order to be able to look at tissues under a microscope, we need to first stain them with the right technique. Learn the main staining techniques used in histology today on our full video: https://khub.me/aux9w

Oh, are you struggling with learning anatomy? We created the ★ Ultimate Anatomy Study Guide ★ to help you kick some gluteus maximus in any topic. Completely free. Download yours today: https://khub.me/e0th1

As you probably know, histology is the study of the microscopic anatomy of cells and tissues. So we use staining methods to visualize and distinguish the different parts of cells and tissues since cells and their structures are usually transparent or colorless. The types of dyes used to color cells and their components can either be specific to particular structures, chemical groups or even molecules, and it can also be non-specific in which case most of the cell is stained in the same way.

When staining tissue samples, dyes that are used are either acidic or basic or a combination of the two. And why is that, you might be asking. Well, cellular structures such as nucleic acids or proteins have charged groups which are known as phosphate groups or carboxyl groups, just to name a couple. The dyes used in histology are colored organic compounds which also have a charge. Acidic dyes carry a negative charge and so they bind to positively-charged cell structures.

In the full version of this tutorial, we will cover some of the most common types of dyes used in histological staining of cells and their structures:
- basic dyes vs acidic dyes vs neutral dyes;
- hematoxylin and eosin;
- PAS - staining;
- Golgi method;
- Toluidine blue;
- Masson's trichrome;
- Osmium tetroxide;

To master this topic, click on the link and carry on watching the full video (available to Premium members): https://khub.me/aux9w !

Want to test your knowledge on the different types of cells and tissues? Take this quiz: https://khub.me/3g19f

Read more on how to interpret different histological sections on this complete article which goes through the different stains used in histology https://khub.me/saimh

For more engaging video tutorials, interactive quizzes, articles and an atlas of Human anatomy and histology, go to https://khub.me/pkvz2

How teeth braces are put
How teeth braces are put Dentist 8,319 Views • 2 years ago

How teeth braces are put

Surprising Facts About High Blood Pressure
Surprising Facts About High Blood Pressure samer kareem 2,053 Views • 2 years ago

Surprising Facts About High Blood PressureMust

Wet Mount
Wet Mount DrHouse 23,292 Views • 2 years ago

A wet mount is the suspension of a small amount of vaginal discharge in a liquid medium. Two liquids are commonly used, normal saline and potassium hydroxide. Each has it's own unique properties that make it useful in this setting

Dilatation and Curettage (part 1 )
Dilatation and Curettage (part 1 ) DrHouse 116,058 Views • 2 years ago

The dilatation and Curettage procedure that is commonly performed (D and C)

Erectile Dysfunction : Causes, symptoms and treatment
Erectile Dysfunction : Causes, symptoms and treatment samer kareem 3,767 Views • 2 years ago

Surgical abortion - end
Surgical abortion - end Paul Jensen 35,723 Views • 2 years ago

The products of a surgical abortion.

Every Ethics Question on a Medical Exam
Every Ethics Question on a Medical Exam DrPhil 123 Views • 2 years ago

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Hemodialysis Blood Flow Circuit Animation
Hemodialysis Blood Flow Circuit Animation Scott 115 Views • 2 years ago

SUBSCRIBE: https://www.youtube.com/c/TVNe....phrologist?sub_confi

An animation of blood flow inside the Hemodialysis circuit.

About Dr. Rifai:
Dr. Ahmad Oussama Rifai is certified by the American Board of Internal Medicine (ABIM) in the specialty of Internal Medicine and the sub-specialty of Nephrology.

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https://www.thevirtualnephrologist.com/rifai/

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Incision and Drainage of a Huge Gluteal Abscess
Incision and Drainage of a Huge Gluteal Abscess Scott 52,151 Views • 2 years ago

Incision and Drainage of a Huge Gluteal Abscess

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