Scleroderma (skleer-oh-DUR-muh) is a group of rare diseases that involve the hardening and tightening of the skin and connective tissues — the fibers that provide the framework and support for your body. In some people, scleroderma affects only the skin. But in many people, scleroderma also harms structures beyond the skin — such as blood vessels, internal organs and the digestive tract. Signs and symptoms vary, depending on which structures are affected. Scleroderma affects women more often than men and most commonly occurs between the ages of 30 and 50. While there is no cure for scleroderma, a variety of treatments can ease symptoms and improve quality of life.

There's only one group of people who really know what happens when you die: the dead. And since the dead won't be revealing their secrets anytime soon, it's up to scientists to explain what happens when a person dies. Death, just like life, is a process, scientists say. The first stage of this process is known as clinical death. It lasts from four to six minutes, beginning when a person stops breathing and the heart stops pumping blood. During this time, there may be enough oxygen in the brain that no permanent brain damage occurs. Other organs, such as the kidneys and eyes, also remain alive throughout clinical death.

The protein inside red blood cells (a) that carries oxygen to cells and carbon dioxide to the lungs is hemoglobin (b). Hemoglobin is made up of four symmetrical subunits and four heme groups. Iron associated with the heme binds oxygen.

Knee replacement, also called arthroplasty, is a surgical procedure to resurface a knee damaged by arthritis. Metal and plastic parts are used to cap the ends of the bones that form the knee joint, along with the kneecap. This surgery may be considered for someone who has severe arthritis or a severe knee injury.

Natural painkiller found in human spit. Compound in saliva could be more powerful than morphine. A new painkilling substance has been discovered that is up to six times more potent than morphine when tested in rats — and it's produced naturally by the human body.

Why Does Thinking Hard Make You Tired?

10 Biggest Babies Ever Born

Transposition of the great arteries is a serious but rare heart defect present at birth (congenital), in which the two main arteries leaving the heart are reversed (transposed). Transposition of the great arteries changes the way blood circulates through the body, leaving a shortage of oxygen in blood flowing from the heart to the rest of the body. Without an adequate supply of oxygen-rich blood, the body can't function properly and your child faces serious complications or death without treatment.

Although the Apgar score was developed in 1952 by an anesthesiologist named Virginia Apgar, you also might hear it referred to as an acronym for: Appearance, Pulse, Grimace, Activity, and Respiration. The Apgar test is usually given to a baby twice: once at 1 minute after birth, and again at 5 minutes after birth.

Spine Examination

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Marfan syndrome is a genetic disorder that affects the body’s connective tissue. Connective tissue holds all the body’s cells, organs and tissue together. It also plays an important role in helping the body grow and develop properly. marfan_general_2.jpg What is Marfan Syndrome?Connective tissue is made up of proteins. The protein that plays a role in Marfan syndrome is called fibrillin-1. Marfan syndrome is caused by a defect (or mutation) in the gene that tells the body how to make fibrillin-1. This mutation results in an increase in a protein called transforming growth factor beta, or TGF-β. The increase in TGF-β causes problems in connective tissues throughout the body, which in turn creates the features and medical problems associated with Marfan syndrome and some related disorders. Because connective tissue is found throughout the body, Marfan syndrome can affect many different parts of the body, as well. Features of the disorder are most often found in the heart, blood vessels, bones, joints, and eyes. Some Marfan features – for example, aortic enlargement (expansion of the main blood vessel that carries blood away from the heart to the rest of the body) – can be life-threatening. The lungs, skin and nervous system may also be affected. Marfan syndrome does not affect intelligence.

Bone tumors develop when cells in the bone divide without control, forming a mass of tissue. Most bone tumors are benign, which means they are not cancer and cannot spread. However, they may still weaken bone and lead to fractures or cause other problems. Bone cancer destroys normal bone tissue and may spread to other parts of the body (called metastasis). Benign Bone Tumors Benign tumors are more common than malignant tumors of the bones. These are a few common types of benign bone tumors: Osteochondroma is the most common benign bone tumor. It is more common in people under age 20. Giant cell tumor is a benign tumor, typically affecting the leg (malignant types of this tumor are uncommon). Osteoid osteoma is a bone tumor, often occurring in long bones, that occurs commonly in the early 20s. Osteoblastoma is a single tumor that occurs in the spine and long bones, mostly in young adults. Enchondroma usually appears in bones of the hand and feet. It often has no symptoms. It is the most common type of hand tumor.

-MEN1 syndrome is composed of hyperparathyroidism, gastrinoma (pancreatic tumor) and pituitary tum or(remember the 3 Ps). Hyperparathyroidism in MEN1 is caused by hyperplasia of the parathyroid glands. Removal of 3 1/2 glands or total parathyroidectomy with autotransplantation is necessary.

Watch that Above Knee Medical Amputation Surgery

Cervical Mucus

A hemolytic transfusion reaction is a serious complication that can occur after a transfusion of blood. The red blood cells that were given in the transfusion are destroyed by the patient's immune system. There are other types of allergic transfusion reactions that do not cause hemolysis.

Art restoration of anterior teeth

Binswanger's disease is a type of vascular dementia that involves white matter infarcts. Patients with this disease usually present with apathy, agitation, and bilateral corticospinal or bulbar signs

patient has fever, hypotension, swelling, and erythema of his left leg. Notably, his leg is more painful to palpation than might be expected after visual inspection. These symptoms are very concerning for necrotizing fasciitis. Necrotizing fasciitis is a fulminant infection of the subcutaneous tissue that spreads rapidly along the fascial planes and leads to extensive tissue necrosis and shock. Treatment • Requires surgical debridement & broad-spectrum antibiotics