This animated video covers statins, fibrates, niacin, bile resins, and ezetimibe. We will discuss mechanisms of action, which part of the lipid profile is affected by each drug, and common side effects.

Many people don't know that they have hepatitis C until they already have some liver damage. This can take many years. Some people who get hepatitis C have it for a short time and then get better. This is called acute hepatitis C. But most people who are infected with the virus go on to develop long-term, or chronic, hepatitis C. Although hepatitis C can be very serious, most people can manage the disease and lead active, full lives.

The pathobiology of MM is complex and the root underlying cause of myeloma is the multistep genetic changes in the postgerminal center B cell. In addition, the bone marrow microenvironment plays a crucial role.[2] The interaction between myeloma cells and the microenvironment is mediated through adhesive interactions via cell-surface receptors, paracrine loops involving several cytokines, such as IL-6, VEGF and IL-10, and suppression of cell-mediated immunity.[2–4] IMiDs modulate many of these interactions leading to decreased myeloma cell growth and survival. Thalidomide was the first IMiD introduced to treat MM. It was initially synthesized in Germany in the late 1950s to treat insomnia and morning sickness. It was withdrawn from the market in 1961 because of its teratogenic effects. Its immunomodulatory properties were realized when it was observed to improve erythema nodosum leprosum, a painful immunologic reaction of leprosy, leading to its approval by the FDA in 1998 with tight prescribing and marketing regulations. Subsequent research showed the diverse mechanism of action of thalidomide including its immunomodulatory effect by inhibition of de novo IgM antibody synthesis,[5] modulation of the T-cell subset by increasing the T-helper cells, inhibitory effects on the TNF-α and antiangiogenic activity leading to its use in MM. Significantly higher response rates in combination with dexamethasone led to its approval in the treatment of newly diagnosed MM in 2006. Lenalidomide, a second-generation IMiD, was developed from the structural backbone of the thalidomide molecule by the addition of an amino group (NH2-) at position 4 of the phthaloyl ring and removal of the carbonyl group (C = O) of the 4-amino-substituted phthaloyl ring (Table 1).[6] In addition to immunomodulatory effects, other mechanisms of action have been described such as direct cytotoxicity via induction of apoptosis, inhibition of cell adhesion molecules and inhibition of growth signals that promote bone marrow angiogenesis

There is nothing that compares to the fresh-faced feeling you have when you leave the aesthetician after a facial. There is just something so freeing about knowing that nasty little buggers like blackheads, whiteheads and all other kinds of heads have been given the heave-ho. That could be why this Facebook video of a blackhead being removed has gone viral. With more than 24 million views, the popular video is weirdly difficult to stop watching.

Ultrasound or ultrasonography is a medical imaging technique that uses high frequency sound waves and their echoes. The technique is similar to the echolocation used by bats, whales and dolphins, as well as SONAR used by submarines. In ultrasound, the following events happen: The ultrasound machine transmits high-frequency (1 to 5 megahertz) sound pulses into your body using a probe. The sound waves travel into your body and hit a boundary between tissues (e.g. between fluid and soft tissue, soft tissue and bone). Some of the sound waves get reflected back to the probe, while some travel on further until they reach another boundary and get reflected. The reflected waves are picked up by the probe and relayed to the machine. The machine calculates the distance from the probe to the tissue or organ (boundaries) using the speed of sound in tissue (5,005 ft/s or1,540 m/s) and the time of the each echo's return (usually on the order of millionths of a second). The machine displays the distances and intensities of the echoes on the screen, forming a two dimensional image like the one shown below.

Ureteral stents are one of the most common devices used by urologists. They are placed with cystoscopic guidance in an operating room setting. Ureteral stents are used to relieve ureteral obstruction, promote ureteral healing following surgery, and to assist with ureteral identification during pelvic surgery. Ureteral stent placement is associated with some degree of morbidity in the majority of patients that ranges from generalized urinary discomfort to urinary tract infection or obstruction. Much of the morbidity is related to the biocompatibility of the materials used to fashion the stent and, to some extent, their design; unfortunately, the ideal stent has yet to be discovered.

The Lansinoh Latch Assist has been designed to extend inverted nipples - watch this video to see how.?

Prostate cancer is the most common cancer among men (after skin cancer), but it can often be treated successfully. If you have prostate cancer or are close to someone who does, knowing what to expect can help you cope. Here you can find out all about prostate cancer, including risk factors, symptoms, how it is found, and how it is treated.

A boxer's fracture is a break through the bones of the hand that form the knuckles. Some doctors use the term "brawler's fracture" rather than "boxer's fracture" because a boxer is not likely to get this injury. The less well-trained brawlers have to learn how to punch without hurting themselves. The metacarpal bones in the hand connect the bones in the finger to the bones in the wrist. There are five metacarpal bones, one to connect each finger to the wrist. All of the metacarpal bones have the same anatomic structure. Each consists of the base, the shaft, the neck, and the head

the elbow is the second most frequently dislocated major joint, after the shoulder. It is the most commonly dislocated joint in children. [1] More than 90% of all elbow dislocations are posterior dislocations. This injury entails disengagement of the coronoid process of the ulna from the trochlea of the humerus with movement posteriorly. [2] The mechanism of injury is typically a fall onto an outstretched hand (FOOSH) with the elbow in extension upon impact.

The treatment of cardiac arrest

http://how-to-get-pregnant.info-pro.co ----- How To Get Pregnant, Ways To Get Pregnant, Best Days To Get Pregnant, Easiest Way To Get Pregnant. Signs of Infertility. What exactly is infertility? The problems with either conceiving a child, or with carrying out the pregnancy to its eventual fruitful end, fall under the definition of infertility. Infertility is the incapability of an individual to become pregnant, in case of females, or the incapability to induce pregnancy, in case of the males. The inability of an individual to carry out a pregnancy to its full term is also dubbed infertility. How does one recognize infertility? What are the signs of infertility? Signs of infertility are not always evident. Most people go through life without knowing there is a problem with their reproductive systems, attributing failed pregnancies to providence. In fact, miscarriages are the most common indicator of infertility. Signs of infertility in women: In women, the signs of infertility are more readily recognized as compared to men. Endometriosis causes the lining of the uterus to grow outside the uterus. Bacterial infections may begin around the uterus and spread to other reproductive organs, resulting in infertility. Fibroids in the uterus are indicative of infertility. Tumors in the cervix often cause stenosis, or narrowing of the cervix, which is a common indicator of infertility. Ovulating before the tenth day and after the twentieth day of one's monthly cycle, pre-menstrual spotting, menopausal symptoms, etc. are indicative of luteal phase defect, and thus in turn are signs too.

Simply put, there isn’t enough room for wisdom teeth because our jaws don’t grow to be big enough to have enough space for them to come in. Since there isn’t enough room for them to erupt properly, wisdom teeth tend to come in at an angle or they don’t fully emerge, which causes problems for the rest of the mouth. Third molars (the wisdom teeth) routinely damage the teeth right next door, called second molars. Dentists recommend removing wisdom teeth before they become a problem and to avoid a more complicated surgery. Read more at Ask the Dentist: https://askthedentist.com/wisdom-teeth-removal/

Watch that video of Removal of a large epidermal cyst in the chest

Watch that video to know the Serious Side Effects of Steroids on The Human Body

Watch that video to know if it is safe to have oral sex or not

Watch that video of Unbelievable Head Infection Exposing a Man's Skull

Watch that Big Fibrodenoma Removal Under Local Anesthesia

This video cover all Medical Laboratory Departments

Watch that video of Ingrown hair turns into Horrible 140-pound tumor in man’s stomach