There are 3 genetic types of FHH based on chromosome location. FHH type 1 accounts for 65% of cases and is due to inactivating mutations in the CASR gene, localized to 3q21.1. This gene encodes the calcium-sensing receptor (CaSR). Loss of CaSR function results in a reduction in the sensitivity of parathyroid and renal cells to calcium levels so hypercalcemia is perceived as normal. The other 35% have either a mutation GNA11 (19p13.3) seen in FHH type 2 or AP2S1 (19q13.2-q13.3) seen in FHH type 3 (see these terms) or in genes not yet discovered. FHH is rarely caused by auto-antibodies against CaSR in those without a mutation.

A silent heart attack is a heart attack that has few, if any, symptoms. You may have never had any symptoms to warn you that you've developed a heart problem, such as chest pain or shortness of breath. Having diabetes or prediabetes puts you at increased risk for heart disease and stroke. You can lower your risk by keeping your blood glucose (also called blood sugar), blood pressure, and blood cholesterol close to the recommended target numbersthe levels suggested by diabetes experts for good health. (

How to Reverse GERD and Leaky Gut

Encopresis is a problem that children age four or older can develop due to chronic (long-term) constipation. With constipation, children have fewer bowel movements than normal, and the bowel movements they do have can be hard, dry, and difficult to pass. The child may avoid using the bathroom to avoid discomfort.

-Osler-Rendu-Weber syndrome is characterized by multiple telangiectasias and vascular lesions of the CNS.

Medication Use During Pregnancy

To learn how to give multiple vaginal orgasms

If you’re thinking about going on the pill, you may have questions. What do birth control pills do? Are birth control pills safe? Here’s all the info on how to use birth control pills.

Three lower limb surgeries that you need to know about.

How a woman's body changes during Pregnancy

During this week your baby's brain form channels and creases with the help of more tissues with greater surface area. Check out this video for detail information on 30 weeks pregnant -

Broca's Aphasia (expressive) When a stroke injures the frontal regions of the left hemisphere, different kinds of language problems can occur. This part of the brain is important for putting words together to form complete sentences. Injury to the left frontal area can lead to what is called Broca's aphasia.

This animation describes surgery for patients with inflammatory bowel disease (IBD) -- IPAA, removal of colon, intestinal resection, & stricturoplasty.

surgical procedure used to remove excess skin and fat from the abdomen and to tighten the muscles of the abdominal wall. Most tummy tuck patients are dealing with the effects of pregnancies and weight loss and find themselves with loose skin in spite of exercise and weight control. Each year, thousands of Americans undergo a tummy tuck to tone, firm and define the abdominal area.

Of the many factors that affect your compatibility with a man, one of the biggest (or smallest) is in his pants. As with humour, interests or habits, the wrong fit can leave you cold. Or traumatised. In a study of 1,661 penises, Dr Debby Herbenick, author of Sex Made Easy, found an almost nine-inch difference in erection size: from 1.6 inches to 10.2. And since absolutely nothing outside the package tells you what to expect with the package, you have to test compatibility the hard way. Sometimes you hit your jackpot, sometimes it's just fine, and sometimes he's the guy on either end of that erection spectrum. These writers have been there, so here's what they learned - and how you can deal (without the gasp reflex).

Chest x-ray, pneumoperitonuem, air under diaphragms

knife spoon and toothbrush removed from stomach

Craft man’s new ear from rib cartilage and the skin on his forearm

The first operation is harvesting the heart from the donor. The donor is usually an unfortunate person who has suffered irreversible brain injury, called "brain death". Very often these are patients who have had major trauma to the head, for example, in an automobile accident. The victim's organs, other than the brain, are working well with the help of medications and other "life support" that may include a respirator or other devices. A team of physicians, nurses, and technicians goes to the hospital of the donor to remove donated organs once brain death of the donor has been determined. The removed organs are transported on ice to keep them alive until they can be implanted. For the heart, this is optimally less than six hours. So, the organs are often flown by airplane or helicopter to the recipient's hospital.

Your body needs bile, but if it has too much cholesterol in it, that makes gallstones more likely. It can also happen if your gallbladder can't empty properly. Pigment stones are more common in people with certain medical conditions, such as cirrhosis (a liver disease) or blood diseases such as sickle cell anemia.