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Normal Skin Histology - Explained by a Dermatopathologist
Normal Skin Histology - Explained by a Dermatopathologist DrPhil 258 Views • 3 years ago

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology)

Topics discussed:

Epidermis:
Layers of epidermis: 0:10
Melanocytes vs Keratinocytes: 5:16
Langerhans cells: 10:10 & 33:30 & 57:30

Dermis:
Papillary and reticular dermis: 11:50
Three types of white empty spaces on a slide: vessels, glands/ducts/cysts, or artifact: 15:25
Blood vessels & nerves: 18:24 & 48:50 & 58:59
Arrector pili & other dermal smooth muscle: 20:00

Adnexal:
Sebaceous gland: 21:10
Hair follicle 23:14
Eccrine sweat glands and ducts 24:45 & 50:00
Gland/duct vs blood vessel 27:20 & 48:50
Apocrine glands: this video https://kikoxp.com/posts/7837 (at 12:30)
Acrosyringium: this video https://kikoxp.com/posts/7837 (at 10:00)

Three types of pink bundles: smooth muscle, nerve, dense connective tissue: 27:50

Acral skin (palm sole) with contact dermatitis 29:37
Parakeratosis 30:00
Perivascular lymphocytes 30:40
Eosinophils vs neutrophils 31:20
Spongiosis with desmosome keratinocyte spines 32:10
Spongiotic vesicles with Langerhans cells 33:30
Normal acral skin (palm & sole) with stratum lucidum 34:20
Normal glomus body/apparatus (canal of Sucquet-Hoyer) 35:40
Nerve 36:46 & 51:50
Adipose tissue (white fat cells) in subcutis with Lochkern 37:55
Normal scalp skin with large anagen hair follicles: 39:30
Hair follicle anatomy (bulb/matrix, inner root sheath, outer root sheath, hair shaft, isthmus, infundibulum): 40:55 (labeled images):
https://kikoxp.com/posts/3661 & https://kikoxp.com/posts/7899
Pacinian corpuscle 50:40
Meissner corpuscle 1:02:28

Dense regular connective tissue (Fascia/Tendon/Ligament) vs Smooth Muscle 53:00

Basic Normal Skin Immunohistochemistry:
-cytokeratin in epidermis: 55:33
-S100 in melanocytes and Langerhans cells and adipocytes: 57:30
-Desmin in smooth muscle (arrector pili and blood vessels): 58:59
-CD31 in endothelial cells of blood vessels: 59:33
-SOX-10 in melanocytes: 1:00:40

Digit/Finger/Toe histology (amputation for subungual acral melanoma) 1:04:10 & 1:08:30
-bone 1:05:40
-glomus body 1:05:15
-tendon/ligament 1:06:10
-artery 1:06:58
-fingernail/toenail 1:08:54
-acrosyringium 1:10:45

Solar elastosis (what wrinkles look like microscopically!) 1:11:50

Other videos you might like:
Tendon vs Nerve Histology Made Simple with the Ramen Noodle Sign (of Fulton) video: https://kikoxp.com/posts/4466
Melanocytes vs Keratinocytes made easy video: https://kikoxp.com/posts/3802
Blood Vessel vs Gland vs Artifact Made Easy video: https://kikoxp.com/posts/4808

The basic normal structures of the skin discussed and described by a dermatopathologist. This material is intended for use by medical students, junior pathology or dermatology residents, or for anyone else studying normal human histology. Special thanks to two of my medical students at UAMS for helping make this video possible. Miki Lindsey convinced me that I really needed to sit down and record this video. Akash Patel took time to edit the video and make it ready for YouTube. My sincere thanks to both of them for helping me overcome procrastination.

Huge thanks to Abigail Cline, a medical student at Medical College of Georgia, for volunteering to type a transcript of this ENTIRE video (over 14,000 words!) so that I could provide closed caption subtitles for those with hearing impairments and for those who may need assistance in understanding spoken English (particularly given how quickly I speak!). You can access a text version of her transcript of my video here: https://kikoxp.com/posts/5390

Correction - I made a mistake in the video. I said that sebaceous gland secretions are turned into smelly substances by bacteria and that this makes body odor. That is incorrect. That is actually true of APOCRINE gland secretions not sebaceous secretions.

Also, in the past I used "keratinocyte" and "squamous cell" interchangeably (this is because in dermatopathology, we see and talk about squamous cell carcinomas all the time, and those tumors are composed of keratinocytes). But technically, in normal skin histology, "squamous cell" refers only to the flattened keratinocytes in the superficial epidermis. Thankfully, a histology PhD colleague pointed this out to me and corrected my lazy nomenclature!

Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB ‬

This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.

Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.

Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Facebook: https://www.facebook.com/JMGardnerMD/

Ectopic Baby Medical Abortion Surgery
Ectopic Baby Medical Abortion Surgery hooda 74,527 Views • 3 years ago

Watch that Ectopic Baby Medical Abortion Surgery

Full Tummy Tuck 3D Video - Dr Landsman
Full Tummy Tuck 3D Video - Dr Landsman Surgeon 296 Views • 3 years ago

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Hypertensive Emergency
Hypertensive Emergency samer kareem 1,782 Views • 3 years ago

Hypertensive emergencies encompass a spectrum of clinical presentations in which uncontrolled blood pressures (BPs) lead to progressive or impending end-organ dysfunction. In these conditions, the BP should be lowered aggressively over minutes to hours. Neurologic end-organ damage due to uncontrolled BP may include hypertensive encephalopathy, cerebral vascular accident/cerebral infarction, subarachnoid hemorrhage, and/or intracranial hemorrhage.[1] Cardiovascular end-organ damage may include myocardial ischemia/infarction, acute left ventricular dysfunction, acute pulmonary edema, and/or aortic dissection. Other organ systems may also be affected by uncontrolled hypertension, which may lead to acute renal failure/insufficiency, retinopathy, eclampsia, or microangiopathic hemolytic anemia.[1] With the advent of antihypertensives, the incidence of hypertensive emergencies has declined from 7% to approximately 1% of patients with hypertension.[2] In addition, the 1-year survival rate associated with this condition has increased from only 20% (prior to 1950) to a survival rate of more than 90% with appropriate medical treatment

Heart Stent Procedure
Heart Stent Procedure Surgeon 221 Views • 3 years ago

Watch to learn more about what happens during a stent procedure.
More information about this procedure and other heart care at BJC: https://www.bjc.org/Services/M....edical-Services/angi

Birmingham Hip Resurfacing Surgery- Vijay Bose_Part 1
Birmingham Hip Resurfacing Surgery- Vijay Bose_Part 1 Dr. Vijay Bose 11,786 Views • 3 years ago

Dr.Vijay C. Bose from Apollo Speciality Hospital chennai perform Birmingham Hip Resurfacing Surgery procedure for a case of Avascular necrosis.The NCP ( Neck Capsule Preserving) approach is being used. Total hip replacement, hip resurfacing simply shaves and caps a few centimeters of bone within the joint. The bone-conserving approach of the Birmingham Hip Resurfacing System.

What is Vaginal Discharge and How To Get Rid Of It?
What is Vaginal Discharge and How To Get Rid Of It? hooda 140,543 Views • 3 years ago

Watch that video to know What is Vaginal Discharge and How To Get Rid Of It?

Breast Exam After Breast implants
Breast Exam After Breast implants Alicia Berger 47,503 Views • 3 years ago

A video showing breast examination after breast implants

Nasal Polyp Removal Animation
Nasal Polyp Removal Animation samer kareem 5,455 Views • 3 years ago

Nasal polyps are associated with inflammation of the lining of your nasal passages and sinuses that lasts more than 12 weeks (chronic rhinosinusitis, also known as chronic sinusitis). However, it's possible — and even somewhat more likely — to have chronic sinusitis without nasal polyps. Nasal polyps themselves are soft and lack sensation, so if they're small you may not be aware you have them. Multiple growths or a large polyp may block your nasal passages and sinuses.

Labiaplasty: Understanding the Anatomy
Labiaplasty: Understanding the Anatomy Mohamed Ibrahim 54,823 Views • 3 years ago

Otto Placik MD. a board certified Chicago based plastic surgeon presents Vulvar Vaginal Genital anatomy lesson reviewing the Vulva, Mons Pubis, clitoral hood, prepuce, frenulum, labia minora & majora, vagina, urethra and fourchette with surgical implications and techniques. Photos pictures and video of anatomic models are reviewed in detail on different models. Great for patients thinking about or planning before labiaplasty or vaginal cosmetic surgery

Successful External Cephalic Version
Successful External Cephalic Version samer kareem 2,287 Views • 3 years ago

Successful External Cephalic Version (ECV) - Turning a breech baby in just 2 minutes!

Swallowing Disorders and Achalasia
Swallowing Disorders and Achalasia samer kareem 10,267 Views • 3 years ago

Achalasia is a neurogenic esophageal motility disorder characterized by impaired esophageal peristalsis and a lack of lower esophageal sphincter relaxation during swallowing. Symptoms are slowly progressive dysphagia, usually to both liquids and solids, and regurgitation of undigested food. Evaluation typically includes manometry, barium swallow, and endoscopy. Treatments include dilation, chemical denervation, surgical myotomy, and peroral endoscopic myotomy.

Female Diaphragm for Contraception
Female Diaphragm for Contraception Scott 6,781 Views • 3 years ago

A diaphragm is a shallow, bendable cup that you put inside your vagina. It covers your cervix during sex to prevent pregnancy.

Endoscopy in Hiatal Hernia
Endoscopy in Hiatal Hernia DrPhil 648 Views • 3 years ago

Endoscopy in Hiatal Hernia.

When Do You Ovulate - How to Know When You Are Ovulating
When Do You Ovulate - How to Know When You Are Ovulating hooda 19,611 Views • 3 years ago

Watch that video to learn How to Know When You Are Ovulating

Puberty In Girls Changes and Stages
Puberty In Girls Changes and Stages hooda 48,554 Views • 3 years ago

All you need to know about Puberty In Girls Changes and Stages

Double Hand Transplant Surgery - Inside the Human Body: Hostile World - BBC One
Double Hand Transplant Surgery - Inside the Human Body: Hostile World - BBC One Surgeon 416 Views • 3 years ago

Subscribe and 🔔 to the BBC 👉 https://bit.ly/BBCYouTubeSub
Watch the BBC first on iPlayer 👉 https://bbc.in/iPlayer-Home http://www.bbc.co.uk/human Richard Edwards undergoes a double hand transplant in which his hands are amputated and replaced with hands from a donor. This is the first time this has been done. Three months later the new hands are already changing his life.

#bbc
All our TV channels and S4C are available to watch live through BBC iPlayer, although some programmes may not be available to stream online due to rights. If you would like to read more on what types of programmes are available to watch live, check the 'Are all programmes that are broadcast available on BBC iPlayer?' FAQ 👉 https://bbc.in/2m8ks6v.

Lumpectomy Surgery Procedure
Lumpectomy Surgery Procedure Surgeon 234 Views • 3 years ago

Lumpectomy means that a focal area of cancer is going to be removed. A lot of patients with a lumpectomy don’t need any specific breast reconstruction, explains Dr. Miguel Angel Medina, Director of Microsurgery with Miami Cancer Institute.
Al the end of surgical treatment, all those patients go on to need radiation therapy. For patients who have large breasts, physicians have to take a larger lumpectomy than normal.

Oxygen Saturation
Oxygen Saturation academyo 16,753 Views • 3 years ago

The video will describe what is oxygen saturation? What is Oxygen content and what is oxygen capacity. Please see my web site for disclaimer.

Structure and Types of Cartilage | Hyaline | Elastic | Fibrocartilage | Connective Tissue Histology
Structure and Types of Cartilage | Hyaline | Elastic | Fibrocartilage | Connective Tissue Histology DrPhil 326 Views • 3 years ago

✨This video is on the structure and functions of the three types of cartilage (Hyaline, Elastic and Fibrocartilage). I hope it helps! ☀️

🌟What's in this video?
0:00 - Intro
0:07 - Connective Tissue Recap
1:16 - Structure of Connective Tissue
1:57 - Structural Components of Cartilage
3:38 - Types of Cartilage
3:49 - Hyaline Cartilage
8:05 - Elastic Cartilage
8:55 - Fibrocartilage

✨ Other videos you may need:
🔅 Connective Tissue : https://youtu.be/xw_ALdt5n-A
🔅 Collagen : https://youtu.be/3e2JYMNS_W4
🔅 Ossification: https://youtu.be/86V9SNWD_No
🔅Histology: https://www.youtube.com/playli....st?list=PL1rG930trF2


💫 For more videos like this, subscribe to my channel!
Byte Size Med: https://youtube.com/channel/UC....ZghvlgylH3r_CWfA18eF

📚Factual References & for Further Reading:
- DiFiore's Atlas of Histology
- Junqueira's Basic Histology
- Gartner's Concise Histology
- Openstax Anatomy and Physiology
https://openstax.org/details/b....ooks/anatomy-and-phy
- Openstax Biology
https://openstax.org/details/books/biology-2e
(The last two are links to open-source references. They are NOT affiliate links)

🌤 Note:
These are just a collection of my notes. So use them the way you would use borrowed notes from a friend. 📝
The images in this video are hand-drawn for illustration and explanation only.✍️ Hence, they may not be anatomically accurate. I am just one person making these videos. If there are any errors, that is unintentional. I try super hard to avoid them. Please let me know if you find any, so it gets clarified for other viewers. Science constantly evolves and changes. New discoveries are made everyday. So some of the information in these videos may become outdated. If you notice that, please let me know so I can update them.










⚡️Disclaimer:
These videos are NOT a substitute for a medical textbook. Textbooks are written by experts (which I do not claim to be), edited, proofread and referenced. Please use them.
The information has been sourced from multiple references as mentioned above. I draw all the pictures myself. But if I have inadvertently infringed on any copyright, that is completely unintentional. I only make these videos to impart education. If I have accidentally violated copyright in any way, do let me know so I can make the necessary changes or give credit to anyone who is owed the same.
These videos are NOT intended for patient education. They are NOT a substitute for diagnosis and treatment by a licensed medical professional. Always seek the advice of a qualified health care provider for any questions you may have regarding any medical condition, so that they can address your individual needs.

🔅They are ONLY meant to help students of medicine and health sciences with studying, and should be used for just that purpose and absolutely nothing else.


Byte Size Med. All Rights Reserved.

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