Depression (major depressive disorder or clinical depression) is a common but serious mood disorder. It causes severe symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or working. To be diagnosed with depression, the symptoms must be present for at least two weeks.

Dysentery is an infection of the intestines causing diarrhoea that contains blood or mucus. There are two main types of dysentery: Shigellosis, or bacillary dysentery, is the most common type experienced in the UK, caused by the shigella bacteria. Amoebic dysentery, also called amoebiasis, is caused by a single-celled parasite called Entamoeba histolytica. This form of dysentery is more common abroad in tropical countries. This article focuses on amoebic dysentery, This is usually caused by poor hygiene or contaminated food or water. Amoebic dysentery is a notifiable disease, so your GP must let the local health authority know if you have contracted it. Causes of amoebic dysentery Once inside the body, amoeba clump together to form a cyst that is protected by the stomach’s digestive acid. When the cyst passes through the intestines it breaks open infecting the body. The amoebae burrow into the intestinal wall and cause small ulcers or abscesses. Cysts exit the body via faeces but are still able to live outside, which is how many people become infected. Severe dysentery is more common in developing countries due to compromised hygiene. You can get sick in a number of ways including: Eating contaminated food Drinking contaminated water Contracting dysentery from another infected person. Symptoms of amoebic dysentery Symptoms can appear as many as 10 days after exposure and infection by the parasite. Signs of infection include: Watery diarrhoea with blood or pus in it Nausea or vomiting Stomach pain High temperature Chills Bleeding from back passage (rectum) Weight loss Loss of appetite. Complications of amoebic dysentery If the parasite gets into your bloodstream it can spread to other parts of your body, including the liver. When this happens you run the risk of developing a liver abscess. Symptoms include: High temperature Weakness Cough Jaundice Nausea Loss of appetite Weight loss

Knee pain facts Knee pain is a common problem with many causes, from acute injuries to complications of medical conditions. Knee pain can be localized to a specific area of the knee or be diffuse throughout the knee. Knee pain is often accompanied by physical restriction. A thorough physical examination will usually establish the diagnosis of knee pain. The treatment of knee pain depends on the underlying cause. The prognosis of knee pain is usually good although it might require surgery or other interventions.

Rotationplasty is a type of autograft wherein a portion of a limb is removed, while the remaining limb below the involved portion is rotated and reattached. This procedure is used when a portion of an extremity is injured or involved with a disease, such as cancer. Typically, the ankle joint becomes the knee joint.

Are you getting enough vitamin B12? Many people don’t, and that deficiency can cause some serious problems. Vitamin B12 does a lot of things for your body. It helps make your DNA and your red blood cells, for examples. Since your body doesn't make vitamin B12, you'll need to get it from animal-based foods or from supplements, and it needs to be consumed on a regular basis. Exactly how much you need and where you should get it from depends on things like your age, the diet you follow, your medical conditions, and in some cases what medications you take.

Indications for intervention in patients with a renal artery aneurysm (RAA) include the following [20, 8, 13, 14] : Rupture Symptomatic RAA - Hypertension (from associated renal artery stenosis, refractory to medical management), pain, renal ischemia or infarction secondary to embolization from the aneurysm sac RAAs in females who are pregnant or are contemplating pregnancy Diameter greater than 2 cm Enlarging RAA RAA associated with acute dissection Currently, there is no consensus regarding the size at which an RAA should be repaired in an asymptomatic patient. Experts have recommended RAA repair at diameters ranging from 1.5 to 3 cm, [8] though most suggest 2 cm. Some reports have even suggest that larger asymptomatic saccular aneurysms may be managed expectantly. Note that aneurysm rupture at a diameter of 1.5 cm has been reported. Complete calcification of the wall of the aneurysm sac manifests in about 40% of patients. This was once believed to confer protection against rupture [21] ; however, this belief has since been questioned. [30] Asymptomatic, small (<2 cm in diameter) RAAs do not usually require treatment. One notable exception is an RAA in a woman who is pregnant or contemplating pregnancy. In view of the increased risk of rupture in such cases, even small asymptomatic aneurysms should be repaired in this population. For diagnosis and preinterventional planning, gadolinium-enhanced magnetic resonance angiography (MRA) and computed tomography (CT) angiography (CTA) with three-dimensional (3D) reconstruction have essentially replaced conventional arteriography. Regular follow-up examination with ultrasonography (US) or CT) is recommended in patients who are treated expectantly. Spontaneous cure by thrombosis of small aneurysms has been described. Further refinements in endovascular techniques may allow more RAAs to be treated in this manner. So far, excellent short- and intermediate-term results have been described in the literature [40] ; however, there remains a need for further long-term outcome data.

What damage does atherosclerosis cause? Plaque may partially or totally block the blood's flow through an artery in the heart, brain, pelvis, legs, arms or kidneys. Some of the diseases that may develop as a result of atherosclerosis include coronary heart disease, angina (chest pain), carotid artery disease, peripheral artery disease (PAD) and chronic kidney disease.

An atrioventricular septal defect (AVSD) is a heart defect in which there are holes between the chambers of the right and left sides of the heart, and the valves that control the flow of blood between these chambers may not be formed correctly

To remove a smaller stone in your ureter or kidney, your doctor may pass a thin lighted tube (ureteroscope) equipped with a camera through your urethra and bladder to your ureter. Once the stone is located, special tools can snare the stone or break it into pieces that will pass in your urine.

The spleen, a spongy, soft organ about as big as a person’s fist, is located in the upper left part of the abdomen, just under the rib cage. The splenic artery brings blood to the spleen from the heart. Blood leaves the spleen through the splenic vein, which drains into a larger vein (the portal vein) that carries the blood to the liver. The spleen has a covering of fibrous tissue (the splenic capsule) that supports its blood vessels and lymphatic vessels. The spleen is made up of two basic types of tissue, each with different functions: White pulp Red pulp The white pulp is part of the infection-fighting (immune) system. It produces white blood cells called lymphocytes, which in turn produce antibodies (specialized proteins that protect against invasion by foreign substances). The red pulp filters the blood, removing unwanted material. The red pulp contains other white blood cells called phagocytes that ingest microorganisms, such as bacteria, fungi, and viruses. It also monitors red blood cells, destroying those that are abnormal or too old or damaged to function properly. In addition, the red pulp serves as a reservoir for different elements of the blood, especially white blood cells and platelets (cell-like particles involved in clotting). However, releasing these elements is a minor function of the red pulp.

The cat's stomach is a sac-like structure designed to store large volumes of food and continue the digestive process. The esophagus carries food to the stomach, where it enters via a valve-like structure called the cardiac sphincter. On the interior surface of the stomach is a series of folds called gastric folds. These folds function to help grind and digest food. The inner stomach lining secretes acids and enzymes to break down food. Once the initial stomach digestive process is complete, the partially digested food exits the stomach through the pyloric sphincter area and then enters the duodenum (first segment of the small intestine). Once eaten, most food leaves the stomach within twelve hours after entering.

6 987 24 MORE How Does Anesthesia Work? Credit: itsmejust | Shutterstock If you’ve ever had surgery, unless you are super tough, you’ve gone through it with the benefit of anesthetics. But, how do these body-numbing elixirs work? Prior to the invention of anesthesia in the mid-1800s, surgeons had to hack off limbs, sew up wounds and remove mysterious growths with nothing to dull the patient's pain but opium or booze. While these drugs may have numbed the patient, they didn’t always completely block the pain, or erase the memory of it. Since then, doctors have gotten much better at putting us out with drug combinations that ease pain, relax muscles and, in some cases, put us in a deep state of hypnosis that gives us temporary amnesia. Today, there are two primary types of anesthesia drugs: those that knockout the whole body (general) and those that only numb things up locally.

Multiple endocrine neoplasia type 2 (MEN2) (also known as "Pheochromocytoma and amyloid producing medullary thyroid carcinoma", "PTC syndrome," and "Sipple syndrome") is a group of medical disorders associated with tumors of the endocrine system. The tumors may be benign or malignant (cancer).

The average human digestive tract is home to as many as 1,000 species of microorganisms. Most of them are harmless -- or even helpful -- under normal circumstances. But when something upsets the balance of these organisms in your gut, otherwise harmless bacteria can grow out of control and make you sick. One of the worst offenders is a bacterium called Clostridium difficile(C. difficile, or C. diff). As the bacteria overgrow they release toxins that attack the lining of the intestines, causing a condition called Clostridium difficilecolitis.

Herpes simplex encephalitis is characterized by acute-onset (<1 week) fever, headaches, seizures, altered mental status, and focal neurologic findings such as hemiparesis or cranial nerve deficits. This patient's weakness/fatigue for >1 week, heart murmur, history of drug abuse, and absence of focal neurologic deficits make endocarditis with mycotic aneurysm more likely than herpes encephalitis

-Almost all the cases of occupational transmission of HIV have been due to transmission via exposure to blood and certain body fluids. The body fluids wherein standard precautions have been recommended include semen, vaginal secretions, and any other body fluid containing visible blood. Other standard precautions, according to the Center for Disease Control and Prevention (CDC), also apply to cerebrospinal, peritoneal, pleural, pericardia!, synovial fluid, or any other tissue, even though the epidemiologic data regarding the risk of HIV transmission from these fluids is insufficient. Standard precautions do not apply to urine, sweat, tears, sputum, vomitus, and nasal secretions or feces, as long as there is no gross visible blood. The occupational transmission of HIV has never been documented from the above sources.

Alpha-1 Antitrypsin Deficiency (Alpha-1) is a genetic (inherited) condition – it is passed from parents to their children through their genes. Alpha-1 may result in serious lung disease in adults and/or liver disease at any age.

Learn about Bicuspid Aortic Valves in this presentation. Bicuspid Aortic Valves are present in about 2% of the population and are the most common congenital disorder. Find out more about a Bicuspid Aortic Valve by visiting the following link:

-Traumatic amputation of a body part requires rapid transport of the appendage, which should be wrapped in a saline-moistened gauze, placed in a plastic bag, and transported in a container filled with ice mixed with either saline or sterile water to best preserve the body part and attempt replantation.

Benzodiazepines are a class of agents that work on the central nervous system, acting selectively on gamma-aminobutyric acid-A (GABA-A) receptors in the brain. GABA is a neurotransmitter that inhibits or reduces the activity of nerve cells (neurons) within the brain. Benzodiazepines open GABA-activated chloride channels, and allow chloride ions to enter the neuron. This makes the neuron negatively charged and resistant to excitation.