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Key facts
Hepatitis B is a viral infection that attacks the liver and can cause both acute and chronic disease.
The virus is transmitted through contact with the blood or other body fluids of an infected person - not through casual contact.
About 2 billion people worldwide have been infected with the virus and about 350 million live with chronic infection. An estimated 600 000 persons die each year due to the acute or chronic consequences of hepatitis B.
About 25% of adults who become chronically infected during childhood later die from liver cancer or cirrhosis (scarring of the liver) caused by the chronic infection.
The hepatitis B virus is 50 to 100 times more infectious than HIV.
Hepatitis B virus is an important occupational hazard for health workers.
Hepatitis B is preventable with a safe and effective vaccine.
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Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus. It is a major global health problem and the most serious type of viral hepatitis. It can cause chronic liver disease and puts people at high risk of death from cirrhosis of the liver and liver cancer.
Worldwide, an estimated two billion people have been infected with the hepatitis B virus (HBV), and more than 350 million have chronic (long-term) liver infections.
A vaccine against hepatitis B has been available since 1982. Hepatitis B vaccine is 95% effective in preventing HBV infection and its chronic consequences, and is the first vaccine against a major human cancer.
Acne can form several types of skin blemish, each with a distinct appearance and symptoms. Most minor acne blemishes respond to at-home care and over-the-counter medications. However, people with severe or long-term acne should speak with a doctor or dermatologist. Acne affects around 80 percent of adolescents and young adults. About 40–50 million Americans have acne at any given time. The following are common types of blemish associated with acne: whiteheads blackheads pustules, which are commonly called pimples papules cysts nodules Each type of acne lesion requires a different treatment. Receiving prompt, correct treatment can reduce the risk of long-term skin complications, such as dark spots and scarring. Acne blemishes fall into two categories, depending on whether or not they cause inflammation of the surrounding skin. Whiteheads Whiteheads Blackheads blackheads are pockets of oxidized melanin on the surface of the skin Papules Papules Pustules (pimples) Pustules (pimples) Nodules Nodules Cysts pus in a cyst 1of6 Noninflammatory acne types Whiteheads and blackheads are types of noninflammatory acne lesion. They are the least severe forms of acne. Noninflammatory blemishes usually do not cause swelling and are not very painful. Whiteheads The medical term for whiteheads is closed comedones. These are small, whitish or flesh-colored spots or bumps. They usually have a white, circular center surrounded by a red halo. A hair will sometimes emerge from the center of a whitehead, or it may appear to be trapped within the blemish. The skin around a whitehead may appear to be tight or wrinkled, especially when the whitehead is large or especially raised. ADVERTISEMENT Approved NSCLC Treatment - HCP Info & Resources Request A Rep & Discover A Therapy For Stage III NSCLC. www.stage-iii-nsclc-therapy.com Whiteheads typically do not cause scarring. Blackheads Blackheads are also called open comedones. They are small, black or dark-colored spots that may appear as slightly raised bumps. The skin around a blackhead usually appears normal, while the center of the blackhead is darker than the surrounding area. The coloration is not a result of trapped dirt. Blackheads are simply whiteheads that have opened and widened. When the contents of a whitehead are exposed to air, they darken. Treatment options Many over-the-counter rinses, moisturizers, gels, toners, and creams can treat noninflammatory acne blemishes. They often contain a mix of active ingredients. The following ingredients in over-the-counter treatments can help to break down whiteheads and blackheads: benzoyl peroxide salicylic acid sulfur resorcinol Also, several home remedies and lifestyle changes can help to reduce most minor-to-mild forms of noninflammatory acne. It may help to try: washing the face with lukewarm water and soap twice daily washing the whole body every 2 days reducing stress eating a healthful, balanced diet staying hydrated avoiding over-washing or irritating the skin limiting exposure to the sun always wearing sunscreen when outdoors People should never pop acne blemishes. Doing so can lead to complications, such as: nodules cysts scarring dark spots pitting Inflammatory acne types Inflammatory acne blemishes include: papules pustules nodules cysts Inflammatory acne is more severe than noninflammatory acne, and this type is more likely to cause complications, such as scarring or pitting. Blemishes or lesions that are inflamed, or red, swollen, and warm to the touch can result from inflammatory acne. Minor-to-mild forms Papules Papules are bumps under the skin's surface. They are solid, tender, pink, and raised, and the skin around a papule is usually slightly swollen and red. Unlike whiteheads, papules have no visible center. Unlike blackheads, the pores of a papule do not appear to be widened. Papules develop when whiteheads or blackheads cause so much irritation that they damage some of the surrounding skin. The damage leads to inflammation. Pustules (pimples) Pustules are larger, tender bumps with a defined circular center. The center is filled with whitish or yellowish pus, and the bump has a pink or red base. Immune cells and bacterial cells collect to form this pus. Pustules typically look like much larger and more inflamed whiteheads. Treatment options Several home remedies and over-the-counter medications can treat minor-to-mild papules and pustules. The following tips can help: washing the affected area with cool water and soap using clean hands or a clean, gentle facecloth twice a day applying a warm compress or cloth to the affected area for 10–15 minutes to encourage trapped debris to rise to the surface using products with benzoyl peroxide to combat bacteria using products with salicylic acid to remove dead skin cells and other debris How do you prevent pimples? How do you prevent pimples? How can you prevent pimples from forming? Learn 15 methods of prevention here, including home remedies, lifestyle changes, and diet tips. READ NOW Moderate-to-severe forms Nodules Nodules are hard, painful, inflamed lumps located deep within the skin. They look like larger, deeper papules and have no visible center or head. This type of acne lesion develops when clogged pores damage tissues and cells deep beneath the skin's surface. Nodules are a severe form of acne blemish, and they can cause skin complications such as dark spots or scarring. Cysts Cysts are very large, soft, painful, red or white lumps situated deep in the skin. They are filled with pus. Cysts form deeper within the skin than nodules, and they are the most severe type of acne blemish. Cysts can also cause skin complications, such as scarring. Treatment options People cannot treat moderate-to-severe inflammatory blemishes at home. These lesions require care from a doctor or dermatologist. The doctor can use many products and procedures to treat nodules and cysts. These include: antibiotics, such as tetracycline, doxycycline, and amoxicillin topical corticosteroids oral contraceptives for hormonal-related acne systematic retinoids, such as isotretinoin steroid injections chemical peels photodynamic therapy to combat bacteria drainage and extraction to remove large cysts What causes acne? young woman with forehead acne When a pore becomes clogged, acne can develop. Normally, dead cells collect in the skin's pores, then slowly rise to the surface of the openings and eventually fall away from the skin. A natural body oil called sebum helps to prevent skin cells from drying out. The glands that produce this oil are attached to the pores. When excess sebum builds up, it can cause dead cells to stick together, forming a mixture that becomes trapped in the pores. Acne occurs when a pore becomes clogged with dead skin cells, natural body oils, and a type of bacteria. These bacteria live on the skin and are called Propionibacterium acnes. If they enter and infect clogged pores, this causes acne blemishes to form. When to see a doctor In cases of minor-to-moderate acne, a person will generally have to use home and over-the-counter remedies consistently for 4–8 weeks before they see results. More severe inflammatory types of acne tend to take much longer to clear up. Speak to a doctor or dermatologist if whiteheads, blackheads, papules, or pustules: are severe do not respond to over-the-counter medications are very painful are very large bleed a lot release a lot of pus cover a significant portion of the face or body cause emotional distress develop very close to sensitive areas, such as the eyes or lips Most active ingredients in over-the-counter products are available in prescription-strength treatments. Dermatologists can also remove lesions that are very large or persistent. They can also remove those that do not respond to other forms of treatment. Always see a doctor or dermatologist about nodules and cysts, because these require medical care. Untreated nodules and cysts and those that have been picked or popped can cause scarring.
Nerves are the organs that make up the peripheral nervous system (PNS). They serve as information pipelines that allow the brain and spinal cord to communicate with other tissues and organs. Inside the nerves are the axon processes of sensory and motor neurons (nerve cells).
Vitamin E is an antioxidant. It may help protect your cells from damage. This essential nutrient occurs naturally in many foods. It’s also available as a dietary supplement. Sometimes, it’s in processed foods. Vitamin E is fat-soluble. This means your body stores and uses it as needed. The term “vitamin E” describes eight different compounds. Alpha-tocopherol is the most active one in humans
Endometrial cancer is a type of cancer that begins in the uterus. The uterus is the hollow, pear-shaped pelvic organ in women where fetal development occurs. Endometrial cancer begins in the layer of cells that form the lining (endometrium) of the uterus. Endometrial cancer is sometimes called uterine cancer. Other types of cancer can form in the uterus, including uterine sarcoma, but they are much less common than endometrial cancer. Endometrial cancer is often detected at an early stage because it frequently produces abnormal vaginal bleeding, which prompts women to see their doctors. If endometrial cancer is discovered early, removing the uterus surgically often cures endometrial cancer.
Shoulder dystocia is a rare emergency that can happen during the end of the second stage of labour. It's all to do with how your baby moves down through your vagina and out into the world. Shoulder dystocia happens when your baby's head has been born, but one of her shoulders becomes stuck.
If they are damaged, waste and fluids build up in your blood instead of leaving your body. Kidney damage from diabetes is called diabetic nephropathy. It begins long before you have symptoms. An early sign of it is small amounts of protein in your urine.
The eyes A close up of a young person's eyes. The eyes are responsible for four-fifths of all the information our brain receives. Here you can find out a bit more about how they work, common problems that affect vision and the work Sightsavers does to treat and prevent avoidable blindness. You can also find out more about the people whose lives have been changed thanks to donations from people like you. How do eyes work? (click image to see enlarged version or click here for text alternative) Graphic of an eye with information about its different parts The images we see are made up of light reflected from the objects we look at. This light enters the eye through the cornea. Because this part of the eye is curved, it bends the light, creating an upside down image on the retina (this is eventually put the right way up by the brain). The retina is a complex part of the eye, but only the very back of it is light sensitive. This part of the retina has roughly the area of a 10p coin, and is packed with photosensitive cells called rods and cones. Cones are the cells responsible for daylight vision. There are three kinds – each responding to a different wavelength of light: red, green and blue. The cones allow us to see images in colour and detail. Rods are responsible for night vision. They are sensitive to light but not to colour. In darkness, the cones do not function at all. How do we see an image? The lens focuses the image. It can do this because it is adjustable – using muscles to change shape and help us focus on objects at different distances. The automatic focusing of the lens is a reflex response and is not controlled by the brain. Once the image is clearly focused on the sensitive part of the retina, energy in the light that makes up that image creates an electrical signal. Nerve impulses can then carry information about that image to the brain through the optic nerve.
If you have multiple sclerosis (MS), you probably had several tests done before you received your diagnosis. There isn’t one test to diagnosis MS, so testing can vary. Doctors can use neurological exams, information about previous symptoms, blood tests, and spinal fluid tests. A magnetic resonance imaging (MRI) scan isn’t used to diagnose MS but rather to rule out other diseases. A diagnosis of MS requires more information than what a scan alone can give. By looking at more than one test or exam result, doctors can get a clearer picture of what’s going on in your body.
A heart attack is a medical emergency. A heart attack usually occurs when a blood clot blocks blood flow to the heart. Without blood, tissue loses oxygen and dies. Symptoms include tightness or pain in the chest, neck, back, or arms, as well as fatigue, lightheadedness, abnormal heartbeat, and anxiety. Women are more likely to have atypical symptoms than men. Treatment ranges from lifestyle changes and cardiac rehabilitation to medications, stents, and bypass surgery.
The rotator cuff is a group of muscles and tendons that surround the shoulder joint, keeping the head of your upper arm bone firmly within the shallow socket of the shoulder. A rotator cuff injury can cause a dull ache in the shoulder, which often worsens when you try to sleep on the involved side. Rotator cuff injuries occur most often in people who repeatedly perform overhead motions in their jobs or sports. Examples include painters, carpenters, and people who play baseball or tennis. The risk of rotator cuff injury also increases with age. Many people recover from rotator cuff disease with physical therapy exercises that improve flexibility and strength of the muscles surrounding the shoulder joint. Sometimes, rotator cuff tears may occur as a result of a single injury. In those circumstances, medical care should be provided as soon as possible. Extensive rotator cuff tears may require surgical repair, transfer of alternative tendons or joint replacement.
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Multiple endocrine neoplasia type 2 (MEN2) is a hereditary condition associated with three primary types of tumors: medullary thyroid cancer, parathyroid tumors, and pheochromocytoma. MEN2 is classified into three subtypes based on clinical features. MEN2A, which affects 60% to 90% of MEN2 families Medullary thyroid cancer: 98% to 100% with MEN2A are affected Pheochromocytoma, a typically benign (noncancerous) tumor of the adrenal glands: 50% with MEN2A affected Parathyroid adenoma (benign tumor) or hyperplasia, meaning increased size, of the parathyroid gland: 5% to 10% with MEN2A affected MEN2B, which affects 5% of MEN2 families Medullary thyroid cancer: 98% to 100% with MEN2B affected Pheochromocytoma: 50% with MEN2B affected Mucosal neuromas, which is a benign tumor of nerve tissue on the tongue, lips and throughout the gastrointestinal tract: 95% to 98% affected Digestive problems caused by disordered nerves in the gastrointestinal tract: 75% to 90% affected Muscle, joint, and spinal problems: 95% affected Typical facial features, including swollen lips and thick eyelids: 75% to 90% affected Familial medullary thyroid cancer (FMTC), which affects 5% to 35% of MEN2 families Medullary thyroid carcinoma only Sources: Gagel RF, Marx SJ. “Multiple endocrine neoplasia.” Williams Textbook of Endocrinology, Chapter 40, 11th ed., Philadelphia, 2008, and Eng C, Clayton D, et al. Grubbs EG, Gagel RF. My, How Things Have Changed in Multiple Endocrine Neoplasia Type 2A! J Clin Endocrinol Metab 100(7):2532-5, 7/2015. PMID: 26151398. What causes MEN2? MEN2 is a genetic condition. This means that the cancer risk and other features of MEN2 can be passed from generation to generation in a family. The gene associated with MEN2 is called RET. A mutation (alteration) in the RET gene gives a person an increased risk of developing medullary thyroid cancer and other tumors associated with MEN2.