St. John's wort (Hypericum perforatum) is an over-the-counter herbal supplement used for its antidepressant, anti-inflammatory, and wound-healing properties. Although it has been prescribed in Europe for mild to moderate depression, negative clinical trials and multiple reports of adverse drug interactions have raised concern about its use. St. John's wort induces various P450 isozymes (CYP 1A2, 2C19, 2C9, and 3A4) and P-glycoprotein systems. Drug interactions with the herbal product can lead to treatment failures with many medications, including hormonal contraceptives, antiretrovirals, immunosuppressive agents, narcotics, anticoagulants, and antifungals. There is also a risk for serotonin syndrome when St. John's wort is used in combination with other serotonergic antidepressants. The lack of strict regulation of herbal products that results in variable quality and content (unknown toxic ingredients or inactive ingredients) is also a concern.

Benzodiazepines are a class of agents that work on the central nervous system, acting selectively on gamma-aminobutyric acid-A (GABA-A) receptors in the brain. GABA is a neurotransmitter that inhibits or reduces the activity of nerve cells (neurons) within the brain. Benzodiazepines open GABA-activated chloride channels, and allow chloride ions to enter the neuron. This makes the neuron negatively charged and resistant to excitation.

This is a video which discusses the Vioptix tOX system of near infrared spectroscopy for the monitoring of free tissue transfer. Having information as to the health of the microvascular anastomosis is critical to improved patient outcome and free tissue survival. With better monitoring, supplementing clinical evaluation, surgeons are able to assess the health of the free tissue better and potentially improve patient outcome. The example in this video is of a free breast reconstruction where the tOX system was used to remotely monitor the free flap. The surgeon can follow the flap real time and more importantly follow trend lines to help predict flap complications.

In 5 minutes find out how and why a normal cell becomes a cancer cell: risk factors and treatment.

Meet Toby, the baby who was born premature at 24 weeks. He may be small, but he's definitely a fighter! Share his story

Uterine fibroid embolization (UFE), also known as uterine artery embolization, is a minimally invasive procedure that is performed by an Interventional Radiologist (IR), a doctor who uses advanced imaging technology to see inside the body without surgery. UFE is often performed as an outpatient service and offers a much shorter recovery time than surgery. For more information on uterine fibroids and all your treatment options, including UFE,

This 13 yrs young girl has had left temporo parietal cavernous angioma ,she came with acute bleed with raised ICT ,aphasia ,right hemiparesis ,leision was excised microsurgically with excellent out come

This animated video is an informative video that provides information regarding Upper Gastro-intestinal Endoscopy. An upper GI endoscopy procedure allows your doctor to view the mucus lining of the upper portion of your gastro-intestinal tract. This includes your oesophagus, stomach and duodenum. Upper endoscopy is used to evaluate symptoms of persistent upper abdominal pain, nausea, vomiting, bleeding, or difficulty in swallowing. The procedure is performed using an endoscope which is a long thin flexible tube a light and a tiny video camera attached to the end. The camera transmits the image to a monitor. Uncomplicated upper endoscopy takes 10-20 minutes, your doctor will gently insert the endoscope through your mouth and then slowly and carefully move it down your oesophagus until it reaches your stomach. An endoscopy for stomach may also be necessary in some cases.

How to examine a patient's wrist if you suspect a scaphoid fracture: by Cape Town Emergency Medicine

Dr. Glenn Barnhart explains the symptoms of mitral valve regurgitation such as becoming short of breath. There are five structures of the mitral valve: annulus, leaflet tissue, chordae tendineae, papillary muscles, and left ventricle. All of these are taken into consideration when the mitral valve is leaking and not working right. There are four degrees of mitral valve regurgitation: mild, moderate, moderately severe,.

Simple or Total Mastectomy. The entire breast is removed, but no lymph nodes are taken in this procedure. Simple mastectomy is most frequently used for further cancer prevention or when the cancer has not spread to the lymph nodes.Oct 29, 2014

Trichinosis (trik-ih-NO-sis), sometimes called trichinellosis (trik-ih-nuh-LOW-sis), is a type of roundworm infection. Roundworm parasites use a host body to live and reproduce. Occurring primarily among meat-eating animals (carnivores) — especially bears, foxes and walruses — the infection is acquired by eating roundworm larvae in raw or undercooked meat. When humans eat undercooked meat containing trichinella larvae, the larvae mature into adult worms in the intestine over several weeks. The adult worms then produce larvae that travel through various tissues, including muscle. Trichinosis is most widespread in rural areas throughout the world. Trichinosis can be treated with medication, though it's not always necessary. It's also easy to prevent.

This animation describes the goals of inflammatory bowel disease (IBD) management and how patients can take an active role in managing their disease.

Venipuncture can be a challenging process for medical professionals especially when a patients veins are difficult to see. VeinViewer uses near infrared light to create a digital image of patient vasculature in real time.

Erectile dysfunction (ED) is the inability to get or keep an erection firm enough for sexual function. It’s a common sexual problem, affecting as many as 30 million men in the United States. Most cases of ED have a physical cause, such as heart disease, diabetes, and obesity. Lifestyle choices like smoking and drinking excessive amounts of alcohol can also lead to ED. But for some men, psychological issues are the root of the problem.

Womb Fight amazing

A ganglion cyst is a tumor or swelling on top of a joint or the covering of a tendon (tissue that connects muscle to bone). It looks like a sac of liquid (cyst). Inside the cyst is a thick, sticky, clear, colorless, jellylike material. Depending on the size, cysts may feel firm or spongy.

Scientists in Switzerland proved in 2012 that electrical-chemical stimulation of the spinal cord could restore lower body movement in paralysed rats.

This is a technique of correcting knock knee (genu valgum) deformity by surgery. Highligh of the technique is that the bone is not cut, but merely weakened. The advantage is that it provides accuracy to the surgeon, and rapid healing. Once corrected, the bone is held in place with a special plate (Tomofix), which permits walking with crutches the very next day.

You May Be Able to Repair Cavities Without Getting a Filling