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Toxoplasmosis (tok-so-plaz-MOE-sis) is a disease that results from infection with the Toxoplasma gondii parasite, one of the world's most common parasites. Toxoplasmosis may cause flu-like symptoms in some people, but most people affected never develop signs and symptoms. For infants born to infected mothers and for people with weakened immune systems, toxoplasmosis can cause extremely serious complications. If you're generally healthy, you probably won't need any treatment for toxoplasmosis. If you are pregnant or have lowered immunity, certain medications can help reduce the infection's severity. The best approach, though, is prevention.

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Hiatal hernias occur when contents of the abdominal cavity protrude through the esophageal hiatus of the diaphragm. Factors that contribute to the development of a hiatal hernia include an enlargement of the esophageal hiatus due to developmental defects, an increased abdominal thoracic pressure gradient, and the depletion of elastic fibers in the phrenoesophageal membrane with aging. There are four different types of hiatal hernias and management varies depending on the type. Type I, also known as a sliding hernia, is a simple displacement of the gastroesophageal junction into the thoracic cavity. The stomach remains in the abdominal cavity. This is the most common type of hiatal hernia, accounting for about 95% of all hiatal hernias. Types II-IV are classified as paraesophageal hernias. Type II occurs when the gastroesophageal junction maintains its position but the gastric fundus herniates through the diaphragmatic hiatus. Type III has both the gastroesophageal junction and the stomach herniate above the diaphragm. When more than 30% of the stomach is herniated into the thoracic cavity, it is termed a “giant” paraesophageal hernia. A patient has a type IV hernia when other organs, such as the colon, in addition to the stomach herniate above the diaphragm.

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Meckel's Diverticulum is a vestigeal remnant of vitellointestinal duct. Its a true diverticulum as it contains all three layers of intestine. It is usually presents at anti mesenteric burder. Usually 2 cm (range 1- 12 cm ) in length, found in 2 % of population , and situated around 2 feet of Ileaocecal junction. 50 % cases it contains gastric mucosa , but may also contain colonic, duodenal or pancreatic mucosa .male : female ration in symptomatic cases is 3 : 1.It may mimic acute appendicitis, so in cases where one is going for surgery for appendicitis , must search for meckel's diverticulum........

Given the common presentation of onychodystrophy, physicians should have a firm grasp of common presentations of conditions like onychomycosis, trachyonychia and psoriasis. Accordingly, this author reviews keys to effective diagnosis and pertinent treatment considerations. Nail cosmesis and discomfort are the main motivators for most of our patients to schedule a podiatric consultation. During that patient visit, it is important for the podiatric practitioner to delve into the cause of the problematic nail change, known as onychodystrophy. Onychodystrophy, which is any alteration of nail morphology, encompasses a wide spectrum of nail disorders. Caused by either exogenous or endogenous factors, nail dystrophy may manifest as a misshapen, damaged, infected or discolored nail unit that may affect the toenails, fingernails or both.

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