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Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome samer kareem 12,752 Views • 2 years ago

Ehlers-Danlos syndrome is a group of disorders that affect the connective tissues that support the skin, bones, blood vessels, and many other organs and tissues. Defects in connective tissues cause the signs and symptoms of Ehlers-Danlos syndrome, which vary from mildly loose joints to life-threatening complications. Previously, there were more than 10 recognized types of Ehlers-Danlos syndrome, differentiated by Roman numerals. In 1997, researchers proposed a simpler classification that reduced the number of major types to six and gave them descriptive names: the classical type (formerly types I and II), the hypermobility type (formerly type III), the vascular type (formerly type IV), the kyphoscoliosis type (formerly type VIA), the arthrochalasia type (formerly types VIIA and VIIB), and the dermatosparaxis type (formerly type VIIC). This six-type classification, known as the Villefranche nomenclature, is still commonly used. The types are distinguished by their signs and symptoms, their underlying genetic causes, and their patterns of inheritance. Since 1997, several additional forms of the condition have been described. These additional forms appear to be rare, affecting a small number of families, and most have not been well characterized.

Mitral valve repair of anterior leaflet perforation and ruptured chordae
Mitral valve repair of anterior leaflet perforation and ruptured chordae samer kareem 17,650 Views • 2 years ago

Mitral valve repair of anterior leaflet perforation and ruptured chordae

Menstrual cycle
Menstrual cycle samer kareem 22,936 Views • 2 years ago

The menstrual cycle is the regular natural change that occurs in the female reproductive system like the uterus and ovaries that make pregnancy possible. The cycle is required for the production of ovocytes, and for the preparation of the uterus for pregnancy.

Nelson's syndrome
Nelson's syndrome samer kareem 4,819 Views • 2 years ago

Nelson syndrome refers to a spectrum of symptoms and signs arising from an adrenocorticotropin (ACTH)–secreting pituitary macroadenoma after a therapeutic bilateral adrenalectomy. The spectrum of clinical features observed relates to the local effects of the tumor on surrounding structures, the secondary loss of other pituitary hormones, and the effects of the high serum concentrations of ACTH on the skin. [1] The first case was reported by Nelson et al in 1958. [2]

Kyphosis
Kyphosis samer kareem 7,636 Views • 2 years ago

Kyphosis, also known as a round back or hunchback, is a condition in which the spine in the upper back has an excessive curvature. The upper back, or thoracic region of the spine, is supposed to have a slight natural curve.

The Scheuermann's Disease
The Scheuermann's Disease samer kareem 9,188 Views • 2 years ago

The gradual curves of the human spine allow the body to absorb many shocks and stresses in daily life. It’s a delicate balance, though, and if part of the spine curves too much, pain and limited mobility may result.

Scoliosis
Scoliosis samer kareem 18,797 Views • 2 years ago

If you look at someone’s back, you’ll see that the spine runs straight down the middle. When a person has scoliosis, their backbone curves to the side. The angle of the curve may be small, large or somewhere in between. But anything that measures more than 10 degrees is considered scoliosis. Doctors may use the letters “C” and “S” to describe the curve of the backbone. You probably don’t look directly at too many spines, but what you might notice about someone with scoliosis is the way they stand. They may lean a little or have shoulders or hips that look uneven. What Causes Scoliosis? In as many as 80% of cases, doctors don’t find the exact reason for a curved spine. Scoliosis without a known cause is what doctors call “idiopathic.” Some kinds of scoliosis do have clear causes. Doctors divide those curves into two types -- structural and nonstructural. In nonstructural scoliosis, the spine works normally, but looks curved. Why does this happen? There are a number of reasons, such as one leg’s being longer than the other, muscle spasms, and inflammations like appendicitis. When these problems are treated, this type of scoliosis often goes away.

How Do Your Lungs Work?
How Do Your Lungs Work? samer kareem 15,952 Views • 2 years ago

The lungs and respiratory system allow oxygen in the air to be taken into the body, while also enabling the body to get rid of carbon dioxide in the air breathed out. Respiration is the term for the exchange of oxygen from the environment for carbon dioxide from the body's cells.

Asthma and COPD
Asthma and COPD samer kareem 14,003 Views • 2 years ago

Asthma and COPD

Here's Why Your Skin Doesn't Rip Easily
Here's Why Your Skin Doesn't Rip Easily samer kareem 4,793 Views • 2 years ago

Here's Why Your Skin Doesn't Rip Easily

Neuropathic Gait Demonstration
Neuropathic Gait Demonstration samer kareem 4,742 Views • 2 years ago

This type of gait is most often seen in peripheral nerve disease where the distal lower extremity is most affected. Because the foot dorsiflexors are weak, the patient has a high stepping gait in an attempt to avoid dragging the toe on the ground.

Herpes Encephalitis
Herpes Encephalitis samer kareem 7,403 Views • 2 years ago

Herpes simplex encephalitis is characterized by acute-onset (<1 week) fever, headaches, seizures, altered mental status, and focal neurologic findings such as hemiparesis or cranial nerve deficits. This patient's weakness/fatigue for >1 week, heart murmur, history of drug abuse, and absence of focal neurologic deficits make endocarditis with mycotic aneurysm more likely than herpes encephalitis

Alpha-1 Antitrypsin Deficiency
Alpha-1 Antitrypsin Deficiency samer kareem 7,821 Views • 2 years ago

Alpha-1 Antitrypsin Deficiency (Alpha-1) is a genetic (inherited) condition – it is passed from parents to their children through their genes. Alpha-1 may result in serious lung disease in adults and/or liver disease at any age.

Liver Cirrhosis
Liver Cirrhosis samer kareem 11,883 Views • 2 years ago

Cirrhosis is a late stage of scarring (fibrosis) of the liver caused by many forms of liver diseases and conditions, such as hepatitis and chronic alcoholism. The liver carries out several necessary functions, including detoxifying harmful substances in your body, cleaning your blood and making vital nutrients.Apr 6, 2016

Treatment Options for Breast Cancer
Treatment Options for Breast Cancer samer kareem 29,157 Views • 2 years ago

For both DCIS and invasive cancer, radiation therapy to the remaining breast tissue is generally recommended after surgery. A lumpectomy may also be called breast-conserving surgery, a partial mastectomy, quadrantectomy, or a segmental mastectomy. A mastectomy is the surgical removal of the entire breast.

Exterior Cerclage
Exterior Cerclage samer kareem 2,218 Views • 2 years ago

Cerclage is indicated in a patient with a history of painless cervical dilation and a second trimester loss. It is also indicated in a patient with a history of preterm birth and a short cervix found on ultrasound between 16-24 weeks gestation. Cerclage placement occurs after the first trimester in case the pregnancy is genetically abnormal and would likely result in a first trimester loss.

Limbal Dermoid Removal
Limbal Dermoid Removal samer kareem 36,781 Views • 2 years ago

Limbal dermoid is a congenital growth on the eye that forms from germline cells that get trapped in this region during embryogenesis. The dermoid often has tissue from multiple germ layers including hair and fat. Dermoids on the eye can cause astigmatism and be unsightly.

St. John's Wort
St. John's Wort samer kareem 4,496 Views • 2 years ago

St. John's wort (Hypericum perforatum) is an over-the-counter herbal supplement used for its antidepressant, anti-inflammatory, and wound-healing properties. Although it has been prescribed in Europe for mild to moderate depression, negative clinical trials and multiple reports of adverse drug interactions have raised concern about its use. St. John's wort induces various P450 isozymes (CYP 1A2, 2C19, 2C9, and 3A4) and P-glycoprotein systems. Drug interactions with the herbal product can lead to treatment failures with many medications, including hormonal contraceptives, antiretrovirals, immunosuppressive agents, narcotics, anticoagulants, and antifungals. There is also a risk for serotonin syndrome when St. John's wort is used in combination with other serotonergic antidepressants. The lack of strict regulation of herbal products that results in variable quality and content (unknown toxic ingredients or inactive ingredients) is also a concern.

Benzodiazepines
Benzodiazepines samer kareem 3,978 Views • 2 years ago

Benzodiazepines are a class of agents that work on the central nervous system, acting selectively on gamma-aminobutyric acid-A (GABA-A) receptors in the brain. GABA is a neurotransmitter that inhibits or reduces the activity of nerve cells (neurons) within the brain. Benzodiazepines open GABA-activated chloride channels, and allow chloride ions to enter the neuron. This makes the neuron negatively charged and resistant to excitation.

Robotic Kidney Implantation Surgery
Robotic Kidney Implantation Surgery samer kareem 14,313 Views • 2 years ago

Because of his weight, Jimmie Jones was on the waiting list for a new kidney for 17 years. University of Illinois Hospital surgeons used robotic surgery to give him a life without dialysis.

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