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Paget's disease of the breast (also known as Paget's disease of the nipple ) is a malignant condition that outwardly may have the appearance of eczema, with skin changes involving the nipple of the breast.
The condition occurs when Paget's cells, which are large and irregular, form in the skin of the nipple. Although Paget believed the cells were not cancerous, it was later proved that the cells were themselves malignant, in addition to indicating underlying breast cancer. Since the condition is often innocuous and limited to a surface appearance, it is sometimes dismissed, despite the fact that it is indicative of a condition (breast cancer) that may prove fatal if left untreated.

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DVT Deep Venous Thrombosis

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Histology of Seminal Vescicles

Specific treatment for menorrhagia is based on a number of factors, including: Your overall health and medical history The cause and severity of the condition Your tolerance for specific medications, procedures or therapies The likelihood that your periods will become less heavy soon Your future childbearing plans Effects of the condition on your lifestyle Your opinion or personal preference Drug therapy for menorrhagia may include: Iron supplements. If you also have anemia, your doctor may recommend that you take iron supplements regularly. If your iron levels are low but you're not yet anemic, you may be started on iron supplements rather than waiting until you become anemic. Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs, such as ibuprofen (Advil, Motrin IB, others) or naproxen (Aleve), help reduce menstrual blood loss. NSAIDs have the added benefit of relieving painful menstrual cramps (dysmenorrhea). Tranexamic acid. Tranexamic acid (Lysteda) helps reduce menstrual blood loss and only needs to be taken at the time of the bleeding. Oral contraceptives. Aside from providing birth control, oral contraceptives can help regulate menstrual cycles and reduce episodes of excessive or prolonged menstrual bleeding. Oral progesterone. When taken for 10 or more days of each menstrual cycle, the hormone progesterone can help correct hormone imbalance and reduce menorrhagia. The hormonal IUD (Mirena). This intrauterine device releases a type of progestin called levonorgestrel, which makes the uterine lining thin and decreases menstrual blood flow and cramping. If you have menorrhagia from taking hormone medication, you and your doctor may be able to treat the condition by changing or stopping your medication.

An increased prevalence of cardiovascular disease (CVD) has been found in women of childbearing age,[1] with the presence of CVD in pregnant women posing a difficult clinical scenario in which the responsibility of the treating physician extends to the unborn fetus. Profound changes occur in the maternal circulation that have the potential to adversely affect maternal and fetal health, especially in the presence of underlying heart conditions. Up to 4% of pregnancies may have cardiovascular complications despite no known prior disease. The European Society of Cardiology has published guidelines on the management of cardiovascular disease during pregnancy.[

Heart Attack vs Cardiac Arrest vs Stroke

Dysentery is an infection of the intestines causing diarrhoea that contains blood or mucus. There are two main types of dysentery: Shigellosis, or bacillary dysentery, is the most common type experienced in the UK, caused by the shigella bacteria. Amoebic dysentery, also called amoebiasis, is caused by a single-celled parasite called Entamoeba histolytica. This form of dysentery is more common abroad in tropical countries. This article focuses on amoebic dysentery, This is usually caused by poor hygiene or contaminated food or water. Amoebic dysentery is a notifiable disease, so your GP must let the local health authority know if you have contracted it. Causes of amoebic dysentery Once inside the body, amoeba clump together to form a cyst that is protected by the stomach’s digestive acid. When the cyst passes through the intestines it breaks open infecting the body. The amoebae burrow into the intestinal wall and cause small ulcers or abscesses. Cysts exit the body via faeces but are still able to live outside, which is how many people become infected. Severe dysentery is more common in developing countries due to compromised hygiene. You can get sick in a number of ways including: Eating contaminated food Drinking contaminated water Contracting dysentery from another infected person. Symptoms of amoebic dysentery Symptoms can appear as many as 10 days after exposure and infection by the parasite. Signs of infection include: Watery diarrhoea with blood or pus in it Nausea or vomiting Stomach pain High temperature Chills Bleeding from back passage (rectum) Weight loss Loss of appetite. Complications of amoebic dysentery If the parasite gets into your bloodstream it can spread to other parts of your body, including the liver. When this happens you run the risk of developing a liver abscess. Symptoms include: High temperature Weakness Cough Jaundice Nausea Loss of appetite Weight loss

Liver transplantation is surgery to remove a diseased or injured liver and replace it with a healthy whole liver or a segment of a liver from another person, called a donor. People with either acute or chronic liver failure may need a liver transplant to survive.

Sickle cell anemia is an inherited form of anemia: This is a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout your body. Normally, your red blood cells are flexible and round, moving easily through your blood vessels. In sickle cell anemia, the red blood cells become rigid and sticky and are shaped like sickles or crescent moons. These irregularly shaped cells can get stuck in small blood vessels, which can slow or block blood flow and oxygen to parts of the body. There's no cure for most people with sickle cell anemia. However, treatments can relieve pain and help prevent further problems associated with sickle cell anemia.

Thoracentesis (THOR-ah-sen-TE-sis) is a procedure to remove excess fluid in the space between the lungs and the chest wall. This space is called the pleural space. Normally, the pleural space is filled with a small amount of fluid—about 4 teaspoons full.

Claudication, which is defined as reproducible ischemic muscle pain, is one of the most common manifestations of peripheral arterial occlusive disease (PAOD) caused by atherosclerosis. Claudication occurs during physical activity and is relieved after a short rest. Pain develops because of inadequate blood flow.

Large Breast Augmentation

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Surgery to replace an aortic valve is done for aortic valve stenosis and aortic valve regurgitation. During this surgery, the damaged valve is removed and replaced with an artificial valve. The valve replacement is typically an open-heart surgery.