Systemic lupus erythematous is an autoimmune condition characterised by damage to organ systems due to autoantibodies and immune complex deposition. Genes, epigenetic changes and environment play a role in its pathogenesis. SLE is a truly multi system disease causing widespread clinical manifestations in almost all organ systems. Autoantibodies in SLE are numerous and mainly include ANA, dsDNA, Sm and others.

A decade ago we thought that Chikungunya was a tropical disease restricted to the rain forests. However, after the 2007 epidemic in Italy and later in the Reunion islands, this dreaded condition has now spread to the Carribean and the Americas. Its an arthropod borne alpha virus which causes fever, polyarthralgia and arthritis. There could be serious complications in the adult such as meningoencephalitis or GBS as well as in neonates. This presentation discusses in detail the clinical features, diagnosis and management of Chikungunya fever. A detailed discussion of its complications is also included. Check out our other videos

Acne can form several types of skin blemish, each with a distinct appearance and symptoms. Most minor acne blemishes respond to at-home care and over-the-counter medications. However, people with severe or long-term acne should speak with a doctor or dermatologist. Acne affects around 80 percent of adolescents and young adults. About 40–50 million Americans have acne at any given time. The following are common types of blemish associated with acne: whiteheads blackheads pustules, which are commonly called pimples papules cysts nodules Each type of acne lesion requires a different treatment. Receiving prompt, correct treatment can reduce the risk of long-term skin complications, such as dark spots and scarring. Acne blemishes fall into two categories, depending on whether or not they cause inflammation of the surrounding skin. Whiteheads Whiteheads Blackheads blackheads are pockets of oxidized melanin on the surface of the skin Papules Papules Pustules (pimples) Pustules (pimples) Nodules Nodules Cysts pus in a cyst 1of6 Noninflammatory acne types Whiteheads and blackheads are types of noninflammatory acne lesion. They are the least severe forms of acne. Noninflammatory blemishes usually do not cause swelling and are not very painful. Whiteheads The medical term for whiteheads is closed comedones. These are small, whitish or flesh-colored spots or bumps. They usually have a white, circular center surrounded by a red halo. A hair will sometimes emerge from the center of a whitehead, or it may appear to be trapped within the blemish. The skin around a whitehead may appear to be tight or wrinkled, especially when the whitehead is large or especially raised. ADVERTISEMENT Approved NSCLC Treatment - HCP Info & Resources Request A Rep & Discover A Therapy For Stage III NSCLC. www.stage-iii-nsclc-therapy.com Whiteheads typically do not cause scarring. Blackheads Blackheads are also called open comedones. They are small, black or dark-colored spots that may appear as slightly raised bumps. The skin around a blackhead usually appears normal, while the center of the blackhead is darker than the surrounding area. The coloration is not a result of trapped dirt. Blackheads are simply whiteheads that have opened and widened. When the contents of a whitehead are exposed to air, they darken. Treatment options Many over-the-counter rinses, moisturizers, gels, toners, and creams can treat noninflammatory acne blemishes. They often contain a mix of active ingredients. The following ingredients in over-the-counter treatments can help to break down whiteheads and blackheads: benzoyl peroxide salicylic acid sulfur resorcinol Also, several home remedies and lifestyle changes can help to reduce most minor-to-mild forms of noninflammatory acne. It may help to try: washing the face with lukewarm water and soap twice daily washing the whole body every 2 days reducing stress eating a healthful, balanced diet staying hydrated avoiding over-washing or irritating the skin limiting exposure to the sun always wearing sunscreen when outdoors People should never pop acne blemishes. Doing so can lead to complications, such as: nodules cysts scarring dark spots pitting Inflammatory acne types Inflammatory acne blemishes include: papules pustules nodules cysts Inflammatory acne is more severe than noninflammatory acne, and this type is more likely to cause complications, such as scarring or pitting. Blemishes or lesions that are inflamed, or red, swollen, and warm to the touch can result from inflammatory acne. Minor-to-mild forms Papules Papules are bumps under the skin's surface. They are solid, tender, pink, and raised, and the skin around a papule is usually slightly swollen and red. Unlike whiteheads, papules have no visible center. Unlike blackheads, the pores of a papule do not appear to be widened. Papules develop when whiteheads or blackheads cause so much irritation that they damage some of the surrounding skin. The damage leads to inflammation. Pustules (pimples) Pustules are larger, tender bumps with a defined circular center. The center is filled with whitish or yellowish pus, and the bump has a pink or red base. Immune cells and bacterial cells collect to form this pus. Pustules typically look like much larger and more inflamed whiteheads. Treatment options Several home remedies and over-the-counter medications can treat minor-to-mild papules and pustules. The following tips can help: washing the affected area with cool water and soap using clean hands or a clean, gentle facecloth twice a day applying a warm compress or cloth to the affected area for 10–15 minutes to encourage trapped debris to rise to the surface using products with benzoyl peroxide to combat bacteria using products with salicylic acid to remove dead skin cells and other debris How do you prevent pimples? How do you prevent pimples? How can you prevent pimples from forming? Learn 15 methods of prevention here, including home remedies, lifestyle changes, and diet tips. READ NOW Moderate-to-severe forms Nodules Nodules are hard, painful, inflamed lumps located deep within the skin. They look like larger, deeper papules and have no visible center or head. This type of acne lesion develops when clogged pores damage tissues and cells deep beneath the skin's surface. Nodules are a severe form of acne blemish, and they can cause skin complications such as dark spots or scarring. Cysts Cysts are very large, soft, painful, red or white lumps situated deep in the skin. They are filled with pus. Cysts form deeper within the skin than nodules, and they are the most severe type of acne blemish. Cysts can also cause skin complications, such as scarring. Treatment options People cannot treat moderate-to-severe inflammatory blemishes at home. These lesions require care from a doctor or dermatologist. The doctor can use many products and procedures to treat nodules and cysts. These include: antibiotics, such as tetracycline, doxycycline, and amoxicillin topical corticosteroids oral contraceptives for hormonal-related acne systematic retinoids, such as isotretinoin steroid injections chemical peels photodynamic therapy to combat bacteria drainage and extraction to remove large cysts What causes acne? young woman with forehead acne When a pore becomes clogged, acne can develop. Normally, dead cells collect in the skin's pores, then slowly rise to the surface of the openings and eventually fall away from the skin. A natural body oil called sebum helps to prevent skin cells from drying out. The glands that produce this oil are attached to the pores. When excess sebum builds up, it can cause dead cells to stick together, forming a mixture that becomes trapped in the pores. Acne occurs when a pore becomes clogged with dead skin cells, natural body oils, and a type of bacteria. These bacteria live on the skin and are called Propionibacterium acnes. If they enter and infect clogged pores, this causes acne blemishes to form. When to see a doctor In cases of minor-to-moderate acne, a person will generally have to use home and over-the-counter remedies consistently for 4–8 weeks before they see results. More severe inflammatory types of acne tend to take much longer to clear up. Speak to a doctor or dermatologist if whiteheads, blackheads, papules, or pustules: are severe do not respond to over-the-counter medications are very painful are very large bleed a lot release a lot of pus cover a significant portion of the face or body cause emotional distress develop very close to sensitive areas, such as the eyes or lips Most active ingredients in over-the-counter products are available in prescription-strength treatments. Dermatologists can also remove lesions that are very large or persistent. They can also remove those that do not respond to other forms of treatment. Always see a doctor or dermatologist about nodules and cysts, because these require medical care. Untreated nodules and cysts and those that have been picked or popped can cause scarring.

Effect of Smoking 30 PACKS of Cigarettes on Your Lungs

Joe Ingles suffered a very bad looking injury on Sunday night in the NBA. In this video we'll review what happened and discuss the possibilities.

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I'm a doctor and a sports fan and this channel is dedicated to exploring the unique medical side of the world of sports, including NBA, MLB, NFL, UFC, and many more! Breaking down the biggest what ifs, historical injuries and stories, and making learning about medicine fun and relevant for all sports fans!

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Laser-assisted in situ keratomileusis (LASIK) eye surgery can correct or improve your sight by using a laser to change the shape of the cornea. Find out more here: https://www.bupa.co.uk/health-....information/eyes-sig and https://www.bupa.co.uk/health-....information/eyes-sig/laser-eye-surgery

The content is intended for general information only and does not replace the need for personal advice from a qualified health professional.

Dr. Ankur Gupta of the Virginia Eye Institute discusses LASIK eye surgery as a method of correcting refractive errors. LASIK was first performed in Virginia on an FDA-approved laser by a VEI surgeon in 1996. Today, Virginia Eye Institute offers both conventional LASIK and custom LASIK with the bladeless IntraLase laser to precisely sculpt your cornea to correct refractive errors.

For more information on the services and procedures offered at Virginia Eye Institute please visit: https://goo.gl/6nX4RZ

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What to expect and how to prepare for your knee replacement surgery

Laparoscopic cholecystectomy is a very safe operation. The overall complication rate is less than 2%. The complication rate for laparoscopic gallbladder surgery is similar to the complication rate for traditional open gallbladder surgery when performed by a properly trained surgeon.

Central Venous Line Placement in the subclavian vein

This video shows how to insert a chest tube

Positive Pressure Ventilation with a face mask and a bag-valve device

operation on the stomach

Demonstrative video of Advanced PRK - No Touch Technique. 100% Laser. In this particular technique there is no need for mechanical device or to cut the corneal flap.

A video showing the inspection of the nose

Heart sounds S1, S2

Dr. Jawad has been performing Bariatric Surgery in Central Florida since 1984, and Laparoscopic Bariatric Surgery since 1999, having completed over 2000 Bariatric Surgical Cases safely, and with great success. Here you can watch Dr. Jawad performing a Laparoscopic Adjustable Gastric Band procedure, with audio commentary describing the procedure.

Histology of the Thyroid gland

Henry Anhalt DO FAAP
Ped Eddo