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Carpal tunnel surgery, also called carpal tunnel release (CTR) and carpal tunnel decompression surgery, is a surgery in which the transverse carpal ligament is divided. It is a treatment for carpal tunnel syndrome and recommended when there is static (constant, not just intermittent) numbness, muscle weakness, or atrophy, and when night-splinting no longer controls intermittent symptoms of pain in the carpal tunnel. In general, milder cases can be controlled for months to years, but severe cases are unrelenting symptomatically and are likely to result in surgical treatment.

Proper placement of sutures enhances the precise approximation of the wound edges, which helps minimize and redistribute skin tension. Wound eversion is essential to maximize the likelihood of good epidermal approximation. Eversion is desirable to minimize the risk of scar depression secondary to tissue contraction during healing. Usually, inversion is not desirable, and it probably does not decrease the risk of hypertrophic scarring in an individual with a propensity for hypertrophic scars. The elimination of dead space, the restoration of natural anatomic contours, and the minimization of suture marks are also important to optimize the cosmetic and functional results.

Juvenile rheumatoid arthritis, also known as juvenile idiopathic arthritis, is the most common type of arthritis in children under the age of 17. Juvenile rheumatoid arthritis causes persistent joint pain, swelling and stiffness. Some children may experience symptoms for only a few months, while others have symptoms for the rest of their lives. Some types of juvenile rheumatoid arthritis can cause serious complications, such as growth problems and eye inflammation. Treatment of juvenile rheumatoid arthritis focuses on controlling pain, improving function and preventing joint damage.

In a small but promising Phase II clinical trial of breast cancer treatment, cryoablation killed 25 early-stage tumors in 13 women. The tumors ranged in size from .5 cm (very small) to 5.8 cm (very large), with an average size of 1.7cm. Patients were first given a local anesthesia with mild sedation before physicians used ultrasound with or without computed tomography (CT) imaging to guide needle-like probes to deliver very low temperature gas to the tumor site. The ultra-cold gas forms a ball of ice around the probe tip, then expands and destroys surrounding tumor cells. A harmless saline solution was first injected into the chest wall and skin of the breast to protect the tissue surrounding the tumor from the freezing effects. Patients experienced very little pain and most healed completely within six months with no complications and with little or no scarring. The cryotherapy margins of each participant were biopsied immediately after the procedures, and all were negative, with no evidence of cancerous tissue. All 13 patients were without recurrence at an average of 18 months and up to five years following the procedure. These results are promising, but larger studies with lengthier follow-up are needed to determine whether cryotherapy as effective as lumpectomy. A study involving cryoablation of mouse tumors at the University of Michigan Comprehensive Cancer Center found that the freezing procedure also works like a vaccine, boosting the immune system to reduce the likelihood of recurrence. Just how quickly the tumor was frozen made a difference: a 30-second freeze killed tumors and also boosted the immune system, inhibiting metastases to the lungs. A slower freezing lasting several minutes destroyed tumors just as effectively, but actually suppressed the immune system, resulting in greater metastases to the lungs.

Carpal tunnel syndrome is a hand and arm condition that causes numbness, tingling and other symptoms. Carpal tunnel syndrome is caused by a pinched nerve in your wrist. A number of factors can contribute to carpal tunnel syndrome, including the anatomy of your wrist, certain underlying health problems and possibly patterns of hand use. Bound by bones and ligaments, the carpal tunnel is a narrow passageway located on the palm side of your wrist. This tunnel protects a main nerve to your hand and the nine tendons that bend your fingers. Compression of the nerve produces the numbness, tingling and, eventually, hand weakness that characterize carpal tunnel syndrome.

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