This patient's age, speech delay, bilateral lower-extremity weakness, apparent increase in calf diameter, and history of a wheelchair-bound uncle are typical of Duchenne muscular dystrophy (DMD). DMD is the most common muscular dystrophy of childhood that affects boys who have inherited a defective dystrophin gene on X-chromosome p21. Weakness begins in the proximal lower-extremity muscles and manifests as difficulty walking, running, jumping, and climbing stairs. Boys may push their arms on their thighs (Gower sign) to transition from sitting to standing.

-Traumatic amputation of a body part requires rapid transport of the appendage, which should be wrapped in a saline-moistened gauze, placed in a plastic bag, and transported in a container filled with ice mixed with either saline or sterile water to best preserve the body part and attempt replantation.

In 5 minutes find out how and why a normal cell becomes a cancer cell: risk factors and treatment.

Craziest Surgeries You'll Never Believe Occurred!

Cases of some sexually transmitted diseases have reached an all-time high, according to a new report from the Centers for Disease Control and Prevention. From 2014 to 2015, there was a 6% increase in diagnosed cases of chlamydia and a 13% increase in gonorrhea.

remove a staggering number of heartworms. If you don't have your pet on heartworm prevention, go to your vet, get your pet tested and put on heartworm prevention right away!

Dumping syndrome is a condition that can develop after surgery to remove all or part of your stomach or after surgery to bypass your stomach to help you lose weight. Also called rapid gastric emptying, dumping syndrome occurs when food, especially sugar, moves from your stomach into your small bowel too quickly. Most people with dumping syndrome develop signs and symptoms, such as abdominal cramps and diarrhea, 10 to 30 minutes after eating. Other people have symptoms one to three hours after eating, and still others have both early and late symptoms. Generally, you can help prevent dumping syndrome by changing your diet after surgery. Changes might include eating smaller meals and limiting high-sugar foods. In more-serious cases o

Everyone feels sad or low sometimes, but these feelings usually pass with a little time. Depression—also called “clinical depression” or a “depressive disorder”—is a mood disorder that causes distressing symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or working. To be diagnosed with depression, symptoms must be present most of the day, nearly every day for at least 2 weeks.

Tourette syndrome (also called Tourette's disorder or simply, "Tourette's") is an abnormal neurological condition characterized by motor and vocal tics. Tics are involuntary, rapid, sudden repetitive movements or sounds. Tics can be classified in a variety of ways. Motor tics can affect any part of the body including the head, neck, face, arms, shoulders, hands, feet, or legs. Facial tics, especially eye blinking, are usually the first symptoms of TS. Vocal tics are sounds that are made involuntarily. Vocal tics can include clearing the throat, coughing, sniffing, grunting, yelping, or shouting. In a few cases, vocal tics can include strange, inappropriate, or obscene words and phrases (called coprolalia). Vocal tics can also appear as constantly repeating the words of others (echolalia).

Psychological counseling can help parents learn to provide an appropriate environment for the child, especially for homework completion. Psychological counseling may also help children and their families deal more effectively with the social and emotional aspects of TS. Counseling can be an important part of treatment and should not be overlooked.

The cause for TS is unknown. Early research suggested that TS is an inherited condition (often, the person's near or distant relatives have had some form of transient or chronic tic disorder or associated symptoms). Recent studies point to a combination of environmental and genetic factors as a cause of the disorder. The specific genes involved in the development of TS are still being investigated. Studies suggest that TS has a neurological basis and results from an abnormality which affects the brain's metabolism of certain neurotransmitters (chemicals in the brain that regulate behavior.) Current research being funded by the Tourette Syndrome Association (TSA) will help provide more information about the causes and genetic factors of TS.

Roman Nowygrod, MD, a surgeon at NewYork-Presbyterian/Columbia University Medical Center, explains the different surgical approaches to treat Peripheral Arterial Disease (PAD).

Here is how surgeons perform knock knee correction surgery. Titanium plate is used to stabilize the affected area. The femur is cut nearly through to help with the stability. Spreaders angle the cut align the leg. The plate is secured with several screws. Synthetic bone graft material is packed in the joint. The patient will be in crutches for 4 to 6 weeks.

As the liver becomes more severely damaged, more obvious and serious symptoms can develop, such as: yellowing of the skin and whites of the eyes (jaundice) swelling in the legs, ankles and feet, due to a build-up of fluid (oedema) swelling in your abdomen, due to a build-up of fluid known as ascites.

Behcet's (beh-CHETS) disease, also called Behcet's syndrome, is a rare disorder that causes blood vessel inflammation throughout your body. The disease can lead to numerous signs and symptoms that may seem unrelated at first. They may include mouth sores, eye inflammation, skin rashes and lesions, and genital sores. The effects of Behcet's disease vary from person to person and may clear up on their own. Treatment involves medications to reduce the signs and symptoms of Behcet's disease and to prevent serious complications, such as blindness.

The heart's conductions system controls the generation and propagation of electric signals or action potentials causing the hearts muscles to contract and the heart to pump blood.

A pneumothorax (noo-moe-THOR-aks) is a collapsed lung. A pneumothorax occurs when air leaks into the space between your lung and chest wall. This air pushes on the outside of your lung and makes it collapse. In most cases, only a portion of the lung collapses.

Tension pneumothorax develops when a lung or chest wall injury is such that it allows air into the pleural space but not out of it (a one-way valve). As a result, air accumulates and compresses the lung, eventually shifting the mediastinum, compressing the contralateral lung, and increasing intrathoracic pressure enough to decrease venous return to the heart, causing shock. These effects can develop rapidly, particularly in patients undergoing positive pressure ventilation.

Frontotemporal dementia is the name for a range of conditions in which cells in the frontal and temporal lobes of the brain are damaged. These lobes control behaviour, emotional responses and language. This means that people will experience changes in personality and behaviour, or may struggle with language – for example, in finding the right word. Frontotemporal dementia is a less common form of dementia which is more likely to affect younger people – those under 65.

Cardiac tamponade is a medical emergency that requires urgent drainage of the pericardial fluid. Preferably, patients should be monitored in an intensive care unit. All patients should receive the following: Oxygen Volume expansion with blood, plasma, dextran, or isotonic sodium chloride solution, as necessary, to maintain adequate intravascular volume - Sagristà-Sauleda et al noted significant increase in cardiac output after volume expansion [24] (see the Cardiac Output calculator) Bed rest with leg elevation - This may help increase venous return Positive-pressure mechanical ventilation should be avoided because it may decrease venous return and aggravate signs and symptoms of tamponade. Inpatient care After pericardiocentesis, leave the intrapericardial catheter in place after securing it to the skin using sterile procedure and attaching it to a closed drainage system via a 3-way stopcock. Periodically check for reaccumulation of fluid, and drain as needed. The catheter can be left in place for 1-2 days and can be used for pericardiocentesis. Serial fluid cell counts can be useful for helping to discover an impending bacterial catheter infection, which could be catastrophic. If the white blood cell (WBC) count rises significantly, the pericardial catheter must be removed immediately. A Swan-Ganz catheter can be left in place for continuous monitoring of hemodynamics and to assess the effect of reaccumulation of pericardial fluid. A repeat echocardiogram and a repeat chest radiograph should be performed within 24 hours.