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Sarcoidosis is an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands. In people with sarcoidosis, abnormal masses or nodules (called granulomas) consisting of inflamed tissues form in certain organs of the body. These granulomas may alter the normal structure and possibly the function of the affected organ(s).
A diagnosis of sarcoidosis is established on the basis of compatible clinical and radiologic findings and histologic evidence of the presence of noncaseous epithelioid cell granulomas in one or more organs and the absence of causative organisms or particulates (16). Granulomas of known causes and local sarcoidlike reactions must be excluded. Granulomatous lesions may result from many conditions, including tuberculosis, berylliosis, leprosy, hypersensitivity pneumonitis, Crohn disease, primary biliary cirrhosis, and fungal disease. Moreover, local sarcoidlike reactions may be seen in lymph nodes that drain a neoplasm or a site of chronic inflammation (19). Such reactions also have been seen in patients who have undergone chemotherapy and radiation therapy (23). If biopsy of lymph nodes or pulmonary or pleural tissue is necessary for diagnosis, one of three techniques may be used: transbronchial biopsy, CT-guided biopsy, or surgical biopsy (24). The use of a surgical technique may be warranted when the results of biopsy with another procedure are not definitive and biopsy of mediastinal lymph nodes, lung, or both is required. This can generally be done with minimally invasive procedures, such as cervical mediastinoscopy, the Chamberlain procedure (a parasternal minithoracotomy for biopsy of the aortopulmonary window or para-aortic nodes), or video-assisted thoracoscopic surgical biopsy (25).
Reactive arthritis is a painful form of inflammatory arthritis (joint disease due to inflammation). It occurs in reaction to an infection by certain bacteria. Most often, these bacteria are in the genitals (Chlamydia trachomatis) or the bowel (Campylobacter, Salmonella, Shigella and Yersinia). Chlamydia most often transmits by sex. It often has no symptoms, but can cause a pus-like or watery discharge from the genitals. The bowel bacteria can cause diarrhea. If you develop arthritis within one month of diarrhea or a genital infection – especially with a discharge – see a health care provider. You may have reactive arthritis. - See more at: https://www.rheumatology.org/i-am-a/patient-caregiver/diseases-conditions/reactive-arthritis#sthash.PukaaQhj.dpuf
Carpal tunnel release is a surgery used to treat and potentially heal the painful condition known as carpal tunnel syndrome. Doctors used to think that carpal tunnel syndrome was caused by an overuse injury or a repetitive motion performed by the wrist or hand, often at work. They now know that it’s most likely a congenital predisposition (something that runs in families) – some people simply have smaller carpal tunnels than others. Carpal tunnel syndrome can also be caused by injury, such as a sprain or fracture, or repetitive use of a vibrating tool. It's also been linked to pregnancy, diabetes, thyroid disease, and rheumatoid arthritis.
Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. There are many types of anemia. Pernicious anemia is a decrease in red blood cells that occurs when the intestines cannot properly absorb vitamin B12.