Asthma was originally described as an inflammatory disease that predominantly involves the central airways. Pathological and physiological evidence reported during the past few years suggests that the inflammatory process extends beyond the central airways to the peripheral airways and the lung parenchyma. The small airways are capable of producing T-helper-2 cytokines, as well as chemokines, and they have recently been recognized as a predominant site of airflow obstruction in asthmatic persons. The inflammation at this distal site has been described as more severe than large airway inflammation. These findings are of great clinical significance, and highlight the need to consider the peripheral airways as a target in any therapeutic strategy for treatment of asthma.

Idiopathic thrombocytopenic purpura (ITP) is a disorder that can lead to easy or excessive bruising and bleeding. The bleeding results from unusually low levels of platelets — the cells that help blood clot. Idiopathic thrombocytopenic purpura, which is also called immune thrombocytopenia, affects children and adults. Children often develop ITP after a viral infection and usually recover fully without treatment. In adults, the disorder is often long term. If you don't have signs of bleeding and your platelet count isn't too low, you may not need any treatment. In rare cases, the number of platelets may be so low that dangerous internal bleeding occurs. Treatment options are available.

Valvular stenosis occurs when one or more heart valves are narrowed, stiffened, thickened or blocked. A variety of treatment options are available for this disorder. Learn more about the treatments on: bit.ly/2g6Mh8f

Overweight does not necessarily equal unhealthy. There are actually plenty of overweight people who are in excellent health (1). Conversely, many normal weight people have the metabolic problems associated with obesity (2). That’s because the fat under the skin is actually not that big of a problem (at least not from a health standpoint, it’s more of a cosmetic problem). It’s the fat in the abdominal cavity, the belly fat, that causes the biggest issues (3). If you have a lot of excess fat around your waistline, even if you’re not very heavy, then you should take some steps to get rid of it. Belly fat is usually estimated by measuring the circumference around your waist. This can easily be done at home with a simple tape measure. Anything above 40 inches (102 cm) in men and 35 inches (88 cm) in women, is known as abdominal obesity. There are actually a few proven strategies that have been shown to target the fat in the belly area more than other areas of the body.

Tennis elbow or lateral epicondylitis is a condition in which the outer part of the elbow becomes sore and tender. The forearm muscles and tendons become damaged from overuse — repeating the same strenuous motions again and again.

Common types of fractures include: Stable fracture. The broken ends of the bone line up and are barely out of place. Open, compound fracture. The skin may be pierced by the bone or by a blow that breaks the skin at the time of the fracture. ... Transverse fracture. ... Oblique fracture. ... Comminuted fracture.

Urinary tract infections (UTIs) are infections of the urethra, bladder, ureters, or the kidneys, which comprise the urinary tract. E. coli bacteria cause the majority of UTIs, but many other bacteria, fungi, and parasites may also cause UTIs. Females have a higher risk for UTIs than most males, probably because of their anatomy; other risk factors for UTIs include any condition that may impede urine flow (e.g., enlarged prostate, kidney stones, congenital urinary tract abnormalities, and inflammation). Patients with catheters or those who undergo urinary surgery and men with enlarged prostates are at higher risk for UTIs.

A C-reactive protein (CRP) test is a blood test that measures the amount of a protein called C-reactive protein in your blood. C-reactive protein measures general levels of inflammation in your body. High levels of CRP are caused by infections and many long-term diseases.

Menopause is the end of menstruation. In clinical terms, you reach menopause when you haven't had a period for 12 months. Vaginal bleeding after menopause isn't normal and should be evaluated by your doctor. For instance, postmenopausal vaginal bleeding can be caused by: Cancer of the uterus, including endometrial cancer and uterine sarcoma Cancer of the cervix or vagina Thinning of the tissues lining the uterus (endometrial atrophy) or vagina (vaginal atrophy) Uterine fibroids Uterine polyps Infection of the uterine lining (endometritis) Medications such as hormone therapy and tamoxifen Pelvic trauma Bleeding from the urinary tract or rectum Excessive overgrowth of the cells that make up the lining of the uterus (endometrial hyperplasia) The cause of your bleeding may be entirely harmless. However, postmenopausal bleeding could result from something serious, so it's important to see your doctor promptly.

Recovery can take 4 to 6 months, depending on the size of the tear and other factors. You may have to wear a sling for 4 to 6 weeks after surgery. Pain is usually managed with medicines. Physical therapy can help you regain the motion and strength of your shoulder.

irregular, curved toenails. footwear that places a lot of pressure on the big toes, such as socks and stockings that are too tight or shoes that are too tight, narrow, or flat for your feet. toenail injury, including stubbing your toe, dropping something heavy on your foot, or kicking a ball repeatedly. poor posture. How can ingrowing toenails be prevented? Cut your nails straight across; do not cut them too short or too low at the sides. ... Keep your feet clean and dry. ... Avoid tight shoes and use cotton socks rather than synthetic. If you have diabetes, you should take extra care when cutting your nails:

Blood enters the heart through two large veins, the inferior and superior vena cava, emptying oxygen-poor blood from the body into the right atrium. As the atrium contracts, blood flows from your right atrium into your right ventricle through the open tricuspid valve.

Sinusitis and Sinus Surgery Explained (Balloon Sinuplasty and Endoscopic Sinus Surgery)

#STOP VIOLENCE AGAINST DOCTORS#SAVE THE DOCTOR

U.S. biotech firm Bioquark recently got approval to move forward with its ReAnima Project, in which it will try to reverse brain death in patients on life support

Digoxin is used to treat heart failure, usually along with other medications. It is also used to treat a certain type of irregular heartbeat (chronic atrial fibrillation). Treating heart failure may help maintain your ability to walk and exercise and may improve the strength of your heart. Treating an irregular heartbeat can decrease the risk for blood clots, an effect that may reduce your risk for a heart attack or stroke.

Angina, stroke and other vascular conditions are often caused by atherosclerosis ('arteriosclerosis') and treated by stenting, where doctors open up a blocked artery in the heart by inserting a sliver of metal into the artery to keep it open. However, there are allegations that far too many stents are being put in when medications and lifestyle changes could do the job just as well if not better.

This medication is used in emergencies to treat very serious allergic reactions to insect stings/bites, foods, drugs, or other substances. Epinephrine acts quickly to improve breathing, stimulate the heart, raise a dropping blood pressure, reverse hives, and reduce swelling of the face, lips, and throat.

Famous Faces With Hepatitis C You share needles and other equipment used to inject illegal drugs. ... You had a blood transfusion or organ transplant before 1992. ... You get a shot with a needle that has infected blood on it. ... You get a tattoo or a piercing with a needle that has infected blood on it.

Squamous cell carcinomas typically appear as persistent, thick, rough, scaly patches that can bleed if bumped, scratched or scraped. They often look like warts and sometimes appear as open sores with a raised border and a crusted surface. In addition to the signs of SCC shown here, any change in a preexisting skin growth, such as an open sore that fails to heal, or the development of a new growth, should prompt an immediate visit to a physician.