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Lipid Lowering Agents
Lipid Lowering Agents samer kareem 2,849 Views • 2 years ago

Lipid-Lowering Agents HMG-CoA reductase inhibitors (statins) These agents inhibit the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase. Note the following: Low-density lipoprotein (LDL) reduction of 25%-60% Examples include Atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin Contraindications include hypersensitivity, active liver disease, pregnancy, lactation, coadministration with strong CYP3A4 inhibitors (selected statins) Vitamin B3 Vitamin B3 inhibits very-low-density lipoprotein (VLDL) synthesis. Note the following: LDL reduction of 10% High-density lipoprotein (HDL) increase of 20% Example includes Niacin (nicotinic acid) Contraindications include hypersensitivity, liver disease, active peptic ulcer, severe hypotension, arterial bleeding Fibrates Fibrates enhance lipoprotein lipase, resulting in increased VLDL catabolism, fatty acid oxidation, and triglycerides elimination. They decrease hepatic extraction of free fatty acids. Note the following: LDL reduction of 15% Triglyceride reduction of 35% Examples include Gemfibrozil, fenofibrate, fenofibrate (micronized), fenofibric acid Contraindications include active liver disease, renal disease, primary biliary cirrhosis, gallbladder disease 2-Azetidiones These agents inhibit sterol transporter at brush border and, consequently, intestinal absorption of cholesterol. LDL reduction of 15% Example includes Ezetimibe Contraindications include hypersensitivity, coadministration with statins (if active liver disease) Bile acid sequestrants These agents lower cholesterol and LDL via bile duct sequestration. Note the following: LDL reduction of 15% Examples include Cholestyramine, colesevelam, colestipol Contraindications include biliary/bowel obstruction, serum triglycerides >300-500 mg/dL, history of hypertriglyceridemia-induced pancreatitis

Pneumothorax Easy explanation
Pneumothorax Easy explanation samer kareem 1,764 Views • 2 years ago

A pneumothorax occurs when some of the tiny air sacs (alveoli) in a baby's lung become overinflated and burst. This causes air to leak into the space between the lung and chest wall (pleural space). The most common cause of pneumothorax is respiratory distress syndrome. This is a condition that occurs in babies who are born too early (premature). The baby's lungs lack the slippery substance (surfactant) that helps them stay open. Therefore, the tiny air sacs are not able to expand as easily. If the baby is put on a breathing machine (mechanical ventilator), there is extra pressure on the baby's lungs, which can sometimes burst the air sacs.

Laparoscopic Appendectomy HD
Laparoscopic Appendectomy HD Doctor 13,064 Views • 2 years ago

High definition video showing laparoscopic appendectomy operation

Breast Massage Technique For Good Breast Health
Breast Massage Technique For Good Breast Health Medical_Videos 18,820 Views • 2 years ago

Breast Massage Technique For Good Breast Health

Symptoms of Kidney Dysfunction
Symptoms of Kidney Dysfunction samer kareem 1,464 Views • 2 years ago

symptoms of kidney dysfunction. I find kidney dysfunction in my patients very frequently. Lower back pain is a common indicator that the kidneys are starting to become irritated. Yes, lower back pain can come from many different areas, but one of the areas I always rule out is kidney congestion.

Abdominal Examination
Abdominal Examination Doctor 147,349 Views • 2 years ago

inspection, auscultation and palpation

Full Obstetric Examination and Normal Delivery
Full Obstetric Examination and Normal Delivery Mohamed 54,351 Views • 2 years ago

Full Obstetric Examination and Normal Delivery medical video

Endoscopic Nasal Polyp Removal
Endoscopic Nasal Polyp Removal Scott 17,689 Views • 2 years ago

Endoscopic Nasal Polypectomy

Excision of Rectovaginal Nodule
Excision of Rectovaginal Nodule Medical_Videos 7,406 Views • 2 years ago

Excision of Rectovaginal Nodule

Pfannenstiel Incision
Pfannenstiel Incision samer kareem 3,680 Views • 2 years ago

A Pfannenstiel incision /ˈfɑːnᵻnʃtiːl/ is a type of abdominal surgical incision that allows access to the abdomen. It is used for gynecologic and orthopedics surgeries, and it is the most common method for performing Caesarian sections today.

Prolapse - Causes, prevention and treatment
Prolapse - Causes, prevention and treatment samer kareem 5,873 Views • 2 years ago

our uterus (or womb) is normally held in place inside your pelvis with various muscles, tissue, and ligaments. Because of pregnancy, childbirth or difficult labor and delivery, in some women these muscles weaken. Also, as a woman ages and with a natural loss of the hormone estrogen, her uterus can drop into the vaginal canal, causing the condition known as a prolapsed uterus.

How to give Enema
How to give Enema Medical_Videos 30,129 Views • 2 years ago

Enema how to apply Animation

Open Heart Surgery
Open Heart Surgery Doctor 92,934 Views • 2 years ago

Open heart (coronary artery bypass, or CABG) surgery is performed in order to reroute, or "bypass," blood around blocked arteries, thereby improving the supply of oxygen-rich blood to the heart. Surgeons usually use an artery from the chest wall to construct the "detour" around the blocked part of the artery. Veins from the legs are also used.

Anatomy of cornea
Anatomy of cornea samer kareem 7,733 Views • 2 years ago

Acute kidney injury: mechanism, diagnosis and management
Acute kidney injury: mechanism, diagnosis and management samer kareem 1,506 Views • 2 years ago

Acute kidney injury is common entity in medical practice. The present definition is based on a serum creatinine rise of more 0.3 mg/dl in 48 hours or less, a 50% increase from the baseline over a period of 07 days or a urine output of less than 0.5 ml/kg/hour for more than 06 hours. The main causes of acute kidney injury may be classified into pre renal, intrinsic or post renal causes. Rapid diagnosis and prompt treatment is essential to prevent mortality or morbidity. This presentation discusses in detail the causes of all three mechanisms, pre-renal, post renal and intrinsic.

Erectile Dysfunction : Causes, symptoms and treatment
Erectile Dysfunction : Causes, symptoms and treatment samer kareem 3,790 Views • 2 years ago

Corneal Crosslinking Procedure for Keratoconus
Corneal Crosslinking Procedure for Keratoconus samer kareem 2,880 Views • 2 years ago

Corneal cross-linking (CXL) is an in-office eye procedure that strengthens the cornea if it's been weakened by keratoconus, other corneal disease, or (rarely) a complication of LASIK surgery. Alternative and brand names for the procedure include corneal cross-linking, corneal collagen cross-linking, C3-R, CCL and KXL.

Tongue Piercing
Tongue Piercing Scott 6,681 Views • 2 years ago

This video demonstrates tongue piercing procedure done OUTSIDE a clinical setting

Hypertensive emergencies!
Hypertensive emergencies! samer kareem 3,665 Views • 2 years ago

A brief description of hypertensive emergencies including its definition, risk factors, clinical manifestations and management

Aphthous ulcers
Aphthous ulcers samer kareem 2,166 Views • 2 years ago

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