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Pediatric febrile seizures, which represent the most common childhood seizure disorder, exist only in association with an elevated temperature. Evidence suggests, however, that they have little connection with cognitive function, so the prognosis for normal neurologic function is excellent in children with febrile seizures. [1] Epidemiologic studies have led to the division of febrile seizures into 3 groups, as follows: Simple febrile seizures Complex febrile seizures Symptomatic febrile seizures Essential update: Starting MMR/MMRV vaccination earlier may reduce seizure risk In a case-series analysis of a cohort of 323,247 US children born from 2004 to 2008, Hambidge et al found that delaying the first dose of measles-mumps-rubella (MMR) or measles-mumps-rubella-varicella (MMRV) vaccine beyond the age of 15 months may more than double the risk of postvaccination seizures in the second year of life. [2, 3] In infants, there was no association between vaccination timing and postvaccination seizures. [3] In the second year of life, however, the incident rate ratio (IRR) for seizures within 7-10 days was 2.65 (95% confidence interval [CI], 1.99-3.55) after first MMR doses at 12-15 months of age, compared with 6.53 (95% CI, 3.15-13.53) after first MMR doses at 16-23 months. For the MMRV vaccine, the IRR for seizures was 4.95 (95% CI, 3.68-6.66) after first doses at 12-15 months, compared with 9.80 (95% CI, 4.35-22.06) for first doses at 16-23 months.
Meckel's Diverticulum is a vestigeal remnant of vitellointestinal duct. Its a true diverticulum as it contains all three layers of intestine. It is usually presents at anti mesenteric burder. Usually 2 cm (range 1- 12 cm ) in length, found in 2 % of population , and situated around 2 feet of Ileaocecal junction. 50 % cases it contains gastric mucosa , but may also contain colonic, duodenal or pancreatic mucosa .male : female ration in symptomatic cases is 3 : 1.It may mimic acute appendicitis, so in cases where one is going for surgery for appendicitis , must search for meckel's diverticulum........
There are twelve cranial nerves in total. The olfactory nerve (CN I) and optic nerve (CN II) originate from the cerebrum. Cranial nerves III – XII arise from the brain stem (Figure 1). They can arise from a specific part of the brain stem (midbrain, pons or medulla), or from a junction between two parts: Midbrain – the trochlear nerve (IV) comes from the posterior side of the midbrain. It has the longest intracranial length of all the cranial nerves. Midbrain-pontine junction – oculomotor (III). Pons – trigeminal (V). Pontine-medulla junction – abducens, facial, vestibulocochlear (VI-VIII). Medulla Oblongata – posterior to the olive: glossopharyngeal, vagus, accessory (IX-XI). Anterior to the olive: hypoglossal (XII). The cranial nerves are numbered by their loca
The dural venous sinuses are spaces between the endosteal and meningeal layers of the dura. They contain venous blood that originates for the most part from the brain or cranial cavity. The sinuses contain an endothelial lining that is continuous into the veins that are connected to them.
Although the exact cause of abdominal aortic aneurysms is unknown, a number of factors may play a role, including: Tobacco use. ... Hardening of the arteries (atherosclerosis). ... High blood pressure. ... Blood vessel diseases in the aorta. ... Infection in the aorta. ... Trauma. ... Heredity.
The Spirotome belongs to the Direct & Frontal type of biopsy systems for taking large core biopsy from virtually every soft tissue in the body. The FDA has approved 13 applications. This video shows how easy it is to take a large core from a thoracic wall tumor mass. The size and quality of the sample allows quantitative molecular biology.
Lipid-Lowering Agents HMG-CoA reductase inhibitors (statins) These agents inhibit the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase. Note the following: Low-density lipoprotein (LDL) reduction of 25%-60% Examples include Atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin Contraindications include hypersensitivity, active liver disease, pregnancy, lactation, coadministration with strong CYP3A4 inhibitors (selected statins) Vitamin B3 Vitamin B3 inhibits very-low-density lipoprotein (VLDL) synthesis. Note the following: LDL reduction of 10% High-density lipoprotein (HDL) increase of 20% Example includes Niacin (nicotinic acid) Contraindications include hypersensitivity, liver disease, active peptic ulcer, severe hypotension, arterial bleeding Fibrates Fibrates enhance lipoprotein lipase, resulting in increased VLDL catabolism, fatty acid oxidation, and triglycerides elimination. They decrease hepatic extraction of free fatty acids. Note the following: LDL reduction of 15% Triglyceride reduction of 35% Examples include Gemfibrozil, fenofibrate, fenofibrate (micronized), fenofibric acid Contraindications include active liver disease, renal disease, primary biliary cirrhosis, gallbladder disease 2-Azetidiones These agents inhibit sterol transporter at brush border and, consequently, intestinal absorption of cholesterol. LDL reduction of 15% Example includes Ezetimibe Contraindications include hypersensitivity, coadministration with statins (if active liver disease) Bile acid sequestrants These agents lower cholesterol and LDL via bile duct sequestration. Note the following: LDL reduction of 15% Examples include Cholestyramine, colesevelam, colestipol Contraindications include biliary/bowel obstruction, serum triglycerides >300-500 mg/dL, history of hypertriglyceridemia-induced pancreatitis
If the artery were severed, blood would flow out unimpeded, although the artery wall would contract in an effort to stop the bleeding. After losing >30% of one's blood volume blood pressure would start dropping, and with less pressure the rate of bleeding would go down. At this stage if the blood loss wasn't replaced the person could die. Losing halve to two thirds of one's blood volume is considered to be fatal even if later on blood transfusion is attempted. One's total blood volume at 70ml/kg is estimated to be between 5 to 7 liters, so that makes a blood loss of between 2,5 to 4,7 L.
If you are tired of dealing with glasses or squinting to read signs in the distance, then you should consider LASIK Eye Surgery. In this outpatient refractive procedure, lasers are used to correct vision issues by changing the structure of the cornea. This may entirely eliminate reliance upon glasses or contacts. In this interactive LASIK Eye Surgery, you will assist in numbing the patient’s eye and cleaning the area for the procedure. With a speculum, you will hold the eye open, mark the cornea using a water-soluble ink, then attach a suction ring to it. After that, a specialized blade device is used to cut into the corneal flap and peel it back so that the laser can clear away corneal tissue underneath. This process corrects the shape of the cornea in less than a minute before putting the corneal flap back in place. After the procedure, we will go over LASIK Eye Surgery recovery instructions. Scrub in and let’s get started!