Small cell lung cancer, which occurs almost exclusively in smokers, is a malignancy characterised by rapid doubling time, high growth fraction and widespread metastasis at presentation. In this presentation, we will briefly discuss the classification of pulmonary Neuro-endocrine tumours by the World Health Organisation followed by a detailed discussion of the clinical features, lab evaluation and management of SCLC, both limited and extended stage. The frontline therapy in small cell lung cancer is etoposide and cisplatin along with thoracic radiotherapy and prophylactic cranial irradiation in patients who have a good response to therapy. Hyperfractionation of radiotherapy may provide some benefit but is also associated with increase incidence of complications. Newer agents for SCLC include Vandetanib and immunotherapy molecules, such as Iplimumab and nivolumab.

If you're pregnant, you're likely paying extra close attention to your body. If you happen to feel a cramp you may worry that it is a sign of a miscarriage. While the first trimester is the most common time for miscarriages, there are other reasons for cramps. Whether it signals a miscarriage depends on when it occurs, the severity of the cramping, and whether you're experiencing other symptoms alongside it.

What is the spleen and what causes an enlarged spleen (splenomegaly)? The spleen sits under your rib cage in the upper left part of your abdomen toward your back. It is an organ that is part of the lymph system and works as a drainage network that defends your body against infection. White blood cells produced in the spleen engulf bacteria, dead tissue, and foreign matter, removing them from the blood as blood passes through it. The spleen also maintains healthy red and white blood cells and platelets; platelets help your blood clot. The spleen filters blood, removing abnormal blood cells from the bloodstream. A spleen is normally about the size of your fist. A doctor usually can't feel it during an exam. But diseases can cause it to swell and become many times its normal size. Because the spleen is involved in many functions, many conditions may affect it.

Each person's knee is different. This is why UC San Diego Health offers several surgical options for knee replacements to tailor care to each person's injury and health. Each surgical approach has benefits for the right surgical candidate. Our surgeons can discuss what option is most appropriate for each person.

To learn more about knee replacement options at UC San Diego Health, visit:
https://health.ucsd.edu/specia....lties/orthopedics/jo

Francis Gonzales, MD, is a board-certified orthopedic surgeon who specializes in adult hip and knee joint replacement surgery. Learn more about Dr. Gonzales: https://providers.ucsd.edu/det....ails/11935/orthopedi

UC San Diego Health is repeatedly ranked among the nation's best in orthopedic care by U.S. News & World Report. We are also a Blue Distinction Center recognized for our treatment expertise and better overall patient results for knee replacement, as well as a designated Center of Excellence for orthopedic care by Optum. This means you'll receive expert, safe and cost-effective care.

UC San Diego Health's orthopedic surgeons are the first and only in San Diego to offer customized knee replacements with the ROSA knee system — for a faster recovery and more natural feeling knee. Talk to one of our surgeons about whether a ROSA knee replacement is right for you. https://health.ucsd.edu/specia....lties/orthopedics/jo#a

Surgical procedure of Tonsillectomy and Adenoidectomy

Ingrown Hair Removal Video

Watch that video to learn How to Give an Intramuscular Injection

minimally invasive procedure is the new gold standard for hemorrhoidectomy, according to American and European experts in the field. The procedure, known as PPH (procedure for prolapse and hemorrhoids) stapled hemorrhoidectomy, combines hemorrhoidal devascularization and repositioning to return the veins to the anal canal. “This year, this is the revolutionary new procedure in the United States,” Gary Hoffman, MD, clinical faculty member in general and colorectal surgery, Cedars-Sinai Medical Center, Los Angeles, told General Surgery News after moderating a live PPH telesurgery at the 2003 annual meeting of the Society of American Gastrointestinal Endoscopic Surgeons.

A gastroscopy is a procedure where a thin, flexible tube called an endoscope is used to look inside the oesophagus (gullet), stomach and first part of the small intestine (duodenum). It's also sometimes referred to as an upper gastrointestinal endoscopy. The endoscope has a light and a camera at one end.

Breast Cancer spreads by 3 mechanisms- local spread, by lymph nodes, or through the blood. Dr. Lorraine Champion, and Dr. Lisa Bailey discuss how breast cancer spreads. They discuss the different methods of spread and how this will affect the treatment of breast cancer.

An OB/GYN nurse from Erlanger Hospital discusses caring for a newborn baby after a circumcision.

http://www.landging.com/plane-animation.html
420 seconds 3d plane animation, designed for Expo 2010 Shanghai Aviation Pavilion.

- A baby born with two heads is expected to survive after doctors removed the parasitic twin that was “feeding off” her blood supply. The baby girl, who is yet to be named, was born via C-section at Ram Snehi Hospital in northern India last month

A normal vaginal epithelial cell is clear, with recognizable contents, and sharp, distinct cell borders.

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Head CT Interpretation Made Easy

Stress-related mucosal disease (SRMD) is an acute, erosive gastritis representing conditions ranging from stress-related injury to stress ulcers (1, 2). Stress-related injury is superficial mucosal damage that presents primarily as erosions, whereas stress ulcers are deep, focal mucosal damage penetrating the submucosa with high risk for gastrointestinal bleeding (2, 3). Mucosal damage has been reported to occur during the first 24 hours of hospital admission in 75% to 100% of intensive care unit (ICU) patients (4, 5). Clinically important gastrointestinal bleeding can cause hemodynamic instability and increase the need for red blood cell transfusions (1). Significant bleeding may also increase the length of stay in the ICU and mortality (1).

Canker sores (Aphthous ulcer) are small, painful ulcers on the inside of the mouth, tongue, lips, or throat.Canker sores are white or yellow and surrounded by a bright red area. They are not cancerous.