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Aplastic anemia is a hematopoietic disorder caused due to T lymphocyte mediated destruction of stem cells resulting in pancytopenia with a cellular bone marrow and normal cell cytogenetics. The causes of aplastic anaemia may be inherited or acquired. The causes and the diagnostic approach, along with spectrum of severity of this disorder is discussed in this presentation. A detailed discussion of the management options, along with pharmacological therapy and supportive therapy in these cases is also discussed. The treatment options include, in addition to a stem cell transplant, anti-thymocyte globulin, cyclosporine, methyprednisolone and eltrombopag (for patients who have failed treatment on combined modality therapy with ATG and cyclosporine)
Burns are classified as first-, second-, or third-degree, depending on how deep and severe they penetrate the skin's surface. First-degree burns affect only the epidermis, or outer layer of skin. The burn site is red, painful, dry, and with no blisters. Mild sunburn is an example.
Step in the Clinic with Dr. Pritesh Singh and get a practical insight into the Clinical Examination of Incisional Hernia.
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The typical radiograph is of a well-defined, rounded, retrocardiac opacity with an air-fluid level. In this image, the radiolucent gas is highlighted in blue, while the gastric contents are highlighted in the green. In many cases of hiatal hernia, there will not be an air bubble below the left hemidiaphragm. This is a relatively expected finding considering that the stomach is no longer in its usual position. The anatomical position of the herniated organ can be further elucidated on the lateral radiograph. Here we can see that the stomach is in the middle mediastinum posterior to the heart and above the diaphragm. Hiatal hernias can look similar to a retrocardiac lung abscess or another cavitary lesion, but it will change in size and shape between radiographs. Large hernias can shift the mediastinum to the right and result in a widening of the carinal angle. They can even give the appearance of cardiomegaly. In this radiograph, the cardiac silhouette is distinctly visible within the confines of the hiatal hernia. To review, a hiatal hernia on an AP chest radiograph typically appears as a round retrocardiac opacity with an air-fluid level.
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Disclaimer: All the information provided by Medical Education for Visual Learners and associated videos are strictly for informational purposes only. It is not intended as a substitute for medical advice from your health care provider or physician. It should not be used to overrule the advice of a qualified healthcare provider, nor to provide advice for emergency medical treatment. If you think that you or someone that you know may be suffering from a medical condition, then please consult your physician or seek immediate medical attention.
Wash your hands thoroughly with soap and water before and after treating the wound. Wash the area with mild soap and running water to reduce the risk of infection. Pat dry. Apply antibiotic ointment and cover with a clean bandage or sterile dressing. Antibiotic prophylaxis should be considered, especially if there is a high risk of infection, such as with cat bites, with puncture wounds, with wounds to the hand, and in persons who are immunosuppressed. Amoxicillin/clavulanate is the first-line prophylactic antibiotic.
During your menstrual period, your uterus contracts to help expel its lining. Hormonelike substances (prostaglandins) involved in pain and inflammation trigger the uterine muscle contractions. Higher levels of prostaglandins are associated with more-severe menstrual cramps.
Doctor Ricky Brown reacts to this surgery simulation of an inguinal hernia repair where they repair the hernia sack and create a mesh for the organ to comfortably rest on.
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An estimated 900,000 knee replacements are performed in the U.S. every year, but experts say about 15% of patients aren’t totally pleased with the outcome. An advancement in technology is focused on improving those outcomes.
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This tutorial is an introduction to the histology of the different tissues in the human body and the cells they are made of. Test yourself on our cells and tissue histology quiz at https://khub.me/jnhny
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A tissue is a group of cells that has a similar structure and acts together to perform one or more specific functions. In this tutorial, we will introduce you to the 4 main types of tissues in the human body: epithelial tissue, connective tissue, muscle tissue and nervous tissue. Epithelial tissue creates protective boundaries and is involved in the diffusion of ions and molecules, whereas connective tissue underlies and supports other tissue types.
Muscle tissue contracts to initiate movement in the body and nervous tissue transmits and integrates information through the central and peripheral nervous systems.
In this video tutorial we will take a closer look at the histology of the main cells and tissues under the microscope.
- 0:33 introduction to histology
- 1:22 epithelial tissue histology and types
- 5:45 function of the basement membrane
- 6:20 connective tissue histology and structure
- 10:53 muscle tissue and types of muscle cells
- 13:11 basics of the nervous system
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For more engaging video tutorials, interactive quizzes, articles and an atlas of Human anatomy and histology, go to https://khub.me/wcyx7
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Arteriosclerosis occurs when the blood vessels that carry oxygen and nutrients from your heart to the rest of your body (arteries) become thick and stiff — sometimes restricting blood flow to your organs and tissues. Healthy arteries are flexible and elastic, but over time, the walls in your arteries can harden, a condition commonly called hardening of the arteries. Atherosclerosis is a specific type of arteriosclerosis, but the terms are sometimes used interchangeably. Atherosclerosis refers to the buildup of fats, cholesterol and other substances in and on your artery walls (plaques), which can restrict blood flow. These plaques can burst, triggering a blood clot. Although atherosclerosis is often considered a heart problem, it can affect arteries anywhere in your body. Atherosclerosis may be preventable and is treatable.