Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized by hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia).

Electrophysiology studies test the electrical activity of your heart to find where an arrhythmia (abnormal heartbeat) is coming from. These results can help you and your doctor decide whether you need medicine, a pacemaker, an implantable cardioverter defibrillator (ICD), cardiac ablation or surgery.

Educational video of male patient receiving an anoscopy.

In this video, Dr. Joe Bresee, with CDC's Influenza Division, describes the symptoms of H1N1 (swine flu) and warning signs to look for that indicate the need for urgent medical attention.

Less than a decade ago, corneal transplantation took a big leap forward with the introduction of Descemet’s stripping endothelial keratoplasty (DSEK), which removes only Descemet’s membrane and the diseased endothelium and replaces them with a thin, tripartite donor graft of posterior corneal stroma, Descemet’s membrane, and healthy endothelium. Then came DSAEK, in which the donor graft is prepared with an automated microkeratome, allowing for easier donor preparation and reproducible results by surgeons and eye bank technicians.1 DSAEK has proved to have many advantages over penetrating keratoplasty (PK) and its endothelial predecessors (see “A Brief History of Endothelial Keratoplasty”). Now DSAEK is being compared with a newer technique, Descemet’s membrane endothelial keratoplasty (DMEK), which has emerged as a promising alternative—grafting only Descemet’s membrane and endothelium, allowing for a pure anatomical replacement of only what was removed and the possibility of even better vision with quicker healing.1 Although indications for these procedures are similar, each has unique benefits and drawbacks. Five cornea surgeons offer their perspectives on the procedures and their thoughts on whether it may be time to move to the newer surgery.

Watch that video to know the Surprising Cause of Pain During Sexual Intercourse

Liddle syndrome is an inherited form of high blood pressure (hypertension). This condition is characterized by severe hypertension that begins unusually early in life, often in childhood, although some affected individuals are not diagnosed until adulthood. Some people with Liddle syndrome have no additional signs or symptoms, especially in childhood. Over time, however, untreated hypertension can lead to heart disease or stroke, which may be fatal.

childbirth twin baby

The term mallet finger has long been used to describe the deformity produced by disruption of the terminal extensor mechanism at the distal interphalangeal (DIP) joint. Mallet finger is the most common closed tendon injury that is seen in athletes; this injury is also common in nonathletes after "innocent" trauma. Mallet finger has also been referred to as drop, hammer, or baseball finger (although baseball accounts for only a small percentage of such injuries).

Cisplatin is in a class of drugs known as platinum-containing compounds used to treat various types of cancers including metastatic testicular and ovarian tumors. The molecule was first discovered in 1845, but did not receive FDA approval until 1978. Today it is known as the "penicillin of cancer drugs," because it is so effective for many different cancers. There are three key players involved in Cisplatin's mechanism: (1) Cisplatin, (2) DNA (3) and an HMG Protein. Most Cisplatin enters the body through active transport, but some molecules are passively defused through the cell membrane. Once in the nucleus, Cisplatin can form an adduct with two consecutive guanine bases within a strand of DNA. The molecule loses its chlorine atoms in exchange for the nitrogen atoms of the target guanines. Cisplatin can bond more tightly with nitrogen because nitrogen balances the platinum charge more effectively than chlorine. It is this adduct-induced DNA bend that allows binding of proteins which contain the high mobility group, HMG domain. Once the protein is bound to the DNA, it inserts a wedge-like phenyl group of phenylalanine 37 into the widened minor groove created by the bend. The tightly bound HMG protein causes destacking of the nucleotide bases, resulting in the DNA helix becoming kinked. In this way, Cisplatin can be thought of as a monkey wrench in the DNA repair system. With the HMG protein bound to the DNA, the modified strand is not repaired properly and so the cell dies. The success of Cisplatin depends on its ratio of efficacy between cancerous and healthy cells.

Men and women have anatomical differences when it comes to genitals, but orgasms are fundamentally very similar. The female orgasm lasts longer than the male, ranging about 20 seconds compared to 3 to 10 seconds, but men do experience more orgasms.

3D scans show still pictures of your baby in three dimensions. 4D scans show moving 3D images of your baby, with time being the fourth dimension. It's natural to be really excited by the prospect of your first scan. But some mums find the standard 2D scans disappointing when all they see is a grey, blurry outline.

Morning erections have colloquially been termed as “morning wood” while scientifically it is called nocturnal penile tumescence. It is a normal and healthy physiological reaction and response that most men experience in their lives. Morning erections are really the ending of a series of erections that happen to men during the night. Healthy men can, on average, have anywhere between three to five erections in a full night of sleep, each of which lasts from 25-35 minutes.

If you look at someone’s back, you’ll see that the spine runs straight down the middle. When a person has scoliosis, their backbone curves to the side. The angle of the curve may be small, large or somewhere in between. But anything that measures more than 10 degrees is considered scoliosis. Doctors may use the letters “C” and “S” to describe the curve of the backbone. You probably don’t look directly at too many spines, but what you might notice about someone with scoliosis is the way they stand. They may lean a little or have shoulders or hips that look uneven. What Causes Scoliosis? In as many as 80% of cases, doctors don’t find the exact reason for a curved spine. Scoliosis without a known cause is what doctors call “idiopathic.” Some kinds of scoliosis do have clear causes. Doctors divide those curves into two types -- structural and nonstructural. In nonstructural scoliosis, the spine works normally, but looks curved. Why does this happen? There are a number of reasons, such as one leg’s being longer than the other, muscle spasms, and inflammations like appendicitis. When these problems are treated, this type of scoliosis often goes away. In structural scoliosis, the curve of the spine is rigid and can’t be reversed

The examination of the groin, hernial orifices and male external genitalia are clinical examinations which undergraduate medical students are commonly less confident about performing competently, due to the lack of clinical exposure.

Squared Notch

Watch that Female to Male Gender Changing Surgery

The cornea occupies the front center part of the outer wall of the eye. It is made of collagen fibers in a very special arrangement so that the cornea is clear. One looks through the cornea to see the iris and pupil. The cornea bends light coming into the eye so that it is focused on the retina.

There are lots of fallacies about the missionary position being the best position for getting pregnant. With the woman on her back and her partner on top, it is thought that gravity will assist the sperm to swim upwards towards the egg.

Facial Tenderness
1. Ask the patient to tell you if these maneuvers causes excessive discomfort or pain. ++
2. Press upward under both eyebrows with your thumbs.
3. Press upward under both maxilla with your thumbs.
4. Excessive discomfort on one side or significant pain suggests sinusitis.

Sinus Trans illumination 1. Darken the room as much as possible. ++
2. Place a bright otoscope or other point light source on the maxilla.
3. Ask the patient to open their mouth and look for an orange glow on the hard palate.
4. A decreased or absent glow suggests that the sinus is filled with something other than air.

Temporomandibular Joint 1. Place the tips of your index fingers directly in front of the tragus of each ear. ++
2. Ask the patient to open and close their mouth.
3. Note any decreased range of motion, tenderness, or swelling.