The occurrence and extent of cerebral infarction is determined by three basic factors: i) site of arterial occlusion, ii) the rapidity of arterial occlusion, and iii) the presence or absence of collateral circulation. Grossly, infarcts are usually divided into pale (non-hemorrhagic) and hemorrhagic types. Infarcts evolve over time, thus their gross appearance gives a clue to when they occurred. The temporal evolution of an infarct occurs in three stages: i) acute (1 day – 1 week) – the involved area is soft and edematous and there is a blurring of anatomic detail; ii) subacute (1 week – 1 month) – there is obvious tissue destruction and liquefactive necrosis of the involved brain; iii) chronic (>1 month) – the damaged tissue has been phagocytized and there is cavition with surrounding gliosis. Microscopically there is also a temporal evolution of cerebral infarcts. During the earliest phase of infarction (0-48 hours) chromatolysis and swollen eosinophilic neurons are seen. Neuronal cell necrosis and an acute inflammatory response are usually seen from 24-72 hours. This response is typically followed by an influx of mononuclear cells which begin to phagocytize necrotic debris (3-5 days). From 1-2 weeks after the infarct there is vascular proliferation and reactive astrocytosis. Over time (>1 month) the necrotic tissue will be completely removed and a cystic cavity surrounded by a glial scar will be formed.

New flu vaccines are released every year to keep up with rapidly adapting flu viruses. Because flu viruses evolve so quickly, last year's vaccine may not protect you from this year's viruses. After vaccination, your immune system produces antibodies that will protect you from the vaccine viruses.

A plastic surgeon in China has successfully grown an artificial ear on a man's arm in a pioneering medical procedure. The patient, surnamed Ji, lost his right ear in an accident and yearned to have it back. Doctor Guo Shuzhong from a hospital in Xi'an, China's Shaanxi Province, used Mr Ji's cartilage from his ribs to build the new ear; and he expects to transplanted the organ to the man's head in about four months. According to the Huanqiu report, Mr Ji sustained serious injuries in the right side of his face in a traffic accident about a year ago. His right ear was torn from his face. The man, whose age is not specified, has since received multiple surgical operations to restore his facial skin and his cheeks. However, he felt frustrated about losing his right ear for good. The patient told a report from China News: 'I lost one ear. I have always felt that I am not complete.' Having sought medical advice from multiple sources, Ji realised that it was impossible to restore his ear through conventional medical procedures as a substantial part of his right ear had gone missing. Upon hearing recommendations, Mr Ji went to see doctor Guo Shuzhong, who works at the First Affiliated Hospital of Xi'an Jiaotong University in the city of Xi'an. Doctor Guo, a renowned plastic surgeon, conducted China's first face transplant operation in 2006, according to China Daily.

The physical signs of pregnancy are easy to recognize -- nausea, fatigue, that swollen belly and (often) a healthy glow. But what if you had these telltale pregnancy symptoms -- and weren't actually pregnant? As crazy as it sounds, it does happen. False pregnancy, or pseudocyesis, is a condition in which a woman believes that she's pregnant, yet conception hasn't taken place and no baby is forming inside. Common, and often lasting, pregnancy symptoms help to reinforce this idea, which can lead a woman to be absolutely certain she's expecting, for months or even years!

Patellar tendon rupture is a rupture of the tendon that connects the patella to the tibia. The superior portion of the patellar tendon attaches on the posterior portion of the patella, and the posterior portion of the patella tendon attaches to the tibial tubercle on the front of the tibia.

A pheochromocytoma (fee-o-kroe-moe-sy-TOE-muh) is a rare, usually noncancerous (benign) tumor that develops in cells in the center of an adrenal gland. You have two adrenal glands, one above each kidney. Your adrenal glands produce hormones that give instructions to virtually every organ and tissue in your body. If you have a pheochromocytoma, an adrenal gland releases hormones that cause persistent or episodic high blood pressure. If left untreated, a pheochromocytoma can result in severe or life-threatening damage to other body systems, especially the cardiovascular system. Most people with a pheochromocytoma are between the ages of 20 and 50, but the tumor can develop at any age. Surgical treatment to remove a pheochromocytoma usually returns blood pressure to normal.

Thyroid nodules are solid or fluid-filled lumps that form within your thyroid, a small gland located at the base of your neck, just above your breastbone. The great majority of thyroid nodules aren't serious and don't cause symptoms. Thyroid cancer accounts for only a small percentage of thyroid nodules. You often won't know you have a thyroid nodule until your doctor discovers it during a routine medical exam. Some thyroid nodules, however, may become large enough to be visible or make it difficult to swallow or breathe.

Hypertrophic cardiomyopathy (HCM) is very common and can affect people of any age. It affects men and women equally. It is a common cause of sudden cardiac arrest in young people, including young athletes. Hypertrophic cardiomyopathy occurs if heart muscle cells enlarge and cause the walls of the ventricles (usually the left ventricle) to thicken. The ventricle size often remains normal, but the thickening may block blood flow out of the ventricle. If this happens, the condition is called obstructive hypertrophic cardiomyopathy. Sometimes the septum, the wall that divides the left and right sides of the heart, thickens and bulges into the left ventricle. This can block blood flow out of the left ventricle. Then the ventricle must work hard to pump blood. Symptoms can include chest pain, dizziness, shortness of breath, or fainting. Hypertrophic cardiomyopathy also can affect the heart's mitral valve, causing blood to leak backward through the valve. Sometimes, the thickened heart muscle doesn't block blood flow out of the left ventricle. This is referred to as non-obstructive hypertrophic cardiomyopathy. The entire ventricle may thicken, or the thickening may happen only at the bottom of the heart. The right ventricle also may be affected. In both obstructive and non-obstructive HCM, the thickened muscle makes the inside of the left ventricle smaller, so it holds less blood. The walls of the ventricle may stiffen, and as a result, the ventricle is less able to relax and fill with blood.

Restrictive cardiomyopathy (RCM) is a rare form of heart muscle disease that is characterized by restrictive filling of the ventricles. In this disease the contractile function (squeeze) of the heart and wall thicknesses are usually normal, but the relaxation or filling phase of the heart is very abnormal.

This operation can be performed as an open or laparoscopic (keyhole procedure). During the operation the sigmoid colon is removed. This involves taking away the blood vessels and lymph nodes to that part of the bowel. The surgeon then re-makes the join (anastomosis) between the remaining left side of the colon and the top of the rectum. The surgeon may use either sutures or special staples to make this join.

Lip augmentation is a cosmetic procedure that can give you fuller, plumper lips. These days, an injectable dermal filler is the most commonly used method of lip augmentation. There are many types of dermal fillers that can be injected in your lips and around your mouth.

The veins around your anus tend to stretch under pressure and may bulge or swell. Swollen veins (hemorrhoids) can develop from an increase in pressure in the lower rectum. Factors that might cause increased pressure include: Straining during bowel movements.

This video: The veins around your anus tend to stretch under pressure and may bulge or swell. Swollen veins (hemorrhoids) can develop from an increase in pressure in the lower rectum. Factors that might cause increased pressure include: Straining during bowel movements.

This short course reviews the main features of EKG tracings. A method for analyzing EKGs is also presented. This method includes assessment of rhythm, calculating heart rate, observing P-wave forms, measurement of EKG intervals and segments and the evaluation of other relevant waves.

Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. No one is sure what causes autoimmune diseases. They do tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases. There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting a diagnosis can be frustrating and stressful. Often, the first symptoms are fatigue, muscle aches and a low fever. The classic sign of an autoimmune disease is inflammation, which can cause redness, heat, pain and swelling. The diseases may also have flare-ups, when they get worse, and remissions, when symptoms get better or disappear. Treatment depends on the disease, but in most cases one important goal is to reduce inflammation. Sometimes doctors prescribe corticosteroids or other drugs that reduce your immune response.

Stomach acid is natural, a valuable chemical contributor to orderly digestion. But in excess or in the wrong place, it's a menace, inflaming and irritating the esophagus, typically causing heartburn and sometimes contributing to the development of ulcers in the stomach and the duodenum, the first part of the small intestine.

Ventricular septal rupture (VSR) is a rare but lethal complication of myocardial infarction (MI). The event occurs 2-8 days after an infarction and often precipitates cardiogenic shock. [1] The differential diagnosis of postinfarction cardiogenic shock should exclude free ventricular wall rupture and rupture of the papillary muscles. (See the image below.)

A Brazilian butt lift (BBL) uses a person's own fat to enhance the size and shape of the buttocks. A plastic surgeon first performs liposuction to remove fat from other areas of the body (often the stomach, hips, and thighs), then injects that fat into the backside. Additional liposuction can be done around the butt to improve the appearance of lift and contour.

Pancreatic Auto Islet Transplantation is a procedure used to maintain insulin production and secretion in patients with chronic pancreatitis that are undergoing a total pancreatectomy, or removal of the entire pancreas. When all other medical therapies fail to control the pain, removal of the pancreas may be an option; however it can leave a person diabetic, which means that the body can no longer control blood sugar levels, and will require intensive testing of blood sugar and injections of insulin. The pancreas is an organ, located in the upper abdominal cavity, behind the stomach, liver and colon. Within the pancreas, specialized clusters of cells known as islets produce insulin, which maintain healthy blood sugar levels. The pancreas also produces enzymes to help digest food. In order to alleviate pain and maintain insulin production, the pancreas is removed from the body, processed and the islets are harvested. Once the pancreas is removed, it is placed in a solution and put into a machine where the pancreas is digested. The islets are then infused into the patient’s liver. Within a short time, the islets are expected to start producing insulin. In 80% of patients, the pain from pancreatitis is relieved by a total pancreatectomy. Over time, some patients may be diabetic and will need to take insulin to maintain healthy blood sugar levels. All patients will take pancreatic enzymes to help digest food after surgery.

What is myositis? Myositis means muscle inflammation, and can be caused by infection, injury, certain medicines, exercise, and chronic disease. Some of the chronic, or persistent, forms are idiopathic inflammatory myopathies, and those are the diseases we discuss here. "Idiopathic" means that the cause is unknown.