The term chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) has been used to identify patients with a chronically progressive or relapsing symmetric sensorimotor disorder with cytoalbuminologic dissociation and interstitial and perivascular endoneurial infiltration by lymphocytes and macrophages. It can be considered the chronic equivalent of acute inflammatory demyelinating polyradiculoneuropathy, the most common form of Guillain-Barré syndrome. Signs and symptoms CIDP typically starts insidiously and evolves slowly, in either a slowly progressive or a relapsing manner, with partial or complete recovery between recurrences; periods of worsening and improvement usually last weeks or months. Most experts consider the necessary duration of symptoms to be greater than 8 weeks for the diagnosis of CIDP to be made. Symptoms reported include the following: Preceding infection (infrequent) Initial limb weakness, both proximal and distal Sensory symptoms (eg, tingling and numbness of hands and feet) Motor symptoms (usually predominant) In about 16% of patients, a relatively acute or subacute onset of symptoms In children, usually a more precipitous onset of symptoms Symptoms of autonomic system dysfunction (eg, orthostatic dizziness) Pertinent physical findings are limited to the nervous system, except when the condition is associated with other diseases. Such findings may include the following. Signs of cranial nerve (CN) involvement (eg, facial muscle paralysis or diplopia) Gait abnormalities Motor deficits (eg, symmetric weakness of both proximal and distal muscles in upper and lower extremities) Diminished or absent deep tendon reflexes Sensory deficits (typically in stocking-glove distribution) Impaired coordination See Clinical Presentation for more detail. Diagnosis Laboratory studies that may be helpful include the following: Cerebrospinal fluid analysis: Elevated protein levels are common (80% of patients); 10% of patients also have mild lymphocytic pleocytosis and increased gamma globulin Complete blood count (CBC), erythrocyte sedimentation rate (ESR), antinuclear antibody (ANA) level, biochemistry profile, and serum and urine immunoelectrophoresis (to exclude associated systemic disorders) In certain instances, genetic testing Other tests and procedures that may be warranted are as follows: MRI of the spine with gadolinium enhancement Electromyography (EMG) is a critical test to determine whether the disorder is truly a peripheral neuropathy and whether the neuropathy is demyelinating Peripheral (sural) nerve biopsy (see the image below): This is considered when the diagnosis is not completely clear, when other causes cannot be excluded, or when profound axonal involvement is observed on EMG; biopsy was once commonly recommended for most patients before immunosuppressive therapy, but current guidelines no longer recommend it

Histology of Lymph Node

In breech position, the baby's bottom is down. There are a few types of breech: Complete breech means the baby is bottom-first, with knees bent. Frank breech means the baby's legs are stretched up, with feet near the head. Footling breech means one leg is lowered over the mother's cervix. You are more likely to have a breech baby if you: Go into early labor Have an abnormally shaped uterus, fibroids, or too much amniotic fluid Have more than one baby in your womb Have placenta previa (when the placenta is on the lower part of the uterine wall, blocking the cervix)

Beating Coronary Heart Surgery

CPR in a patient with Advanced Airway Managment such as a patient with endotracheal tube or combitube is different than performin normal CPR. This video shows how to perform that.

Hip examination by Harvard medical school

How to remove the Intra Uterine Device (IUD)

Kendall Lee, M.D., describes deep brain stimulation surgery, and how it is is typically done with patients who remain awake, so neurological functions can be measured and maintained. For more information on deep brain stimulation, visit http://mayocl.in/2A09T80.

Level of fundus and exam

On Tuesday May 29th at 3:00pm EDT, University Hospitals Case Medical Center Cleveland, Ohio, will host a live webcast to demonstrate the removal of brain tumor and epileptic focus from an awake patient using intra-operative MRI and brain mapping. See this on OR-Live.com

The patient was a middle-aged gentleman with new onset seizures. An MRI showed what appeared to be a low grade glioma near the motor strip on the right. Studies have shown that complete removal can cure the seizures, improve quality of life and survival, but this is difficult to do with conventional technology without harming the surrounding normal brain because its difficult to determine where tumor ends and normal brain begins.

Endoscopic fenestration of suprasellar cyst in a 4 years old girl

Neuroanatomy of CSF Flow

Endoscopy of Mammary Ducts with Micro-Endoscope called Mammary Ductoscopy. Indication:- Nipple Discharge. In this case Papilloma seen quite clearly. Biopsy can also be possible with Ductoscopy. Mammary Ductoscopy is very useful for diagnosis of Breast Cancer in early stage.

A little boy with a mystifying eye condition finally found an answer on the other side of the globe with the help of Dr. Harry Chugani at Children's Hospital of Michigan. ~ Detroit Medical Center

Drop Arm Test

“Complete cure from groin hernia is now possible with Dr.Desarda's repair technique.......” Mesh is a foreign body. Therefore, its use in hernia repairs is known to cause all sorts of complications like pain, recurrence, infection etc. We have developed an innovative new technique of inguinal hernia repair without mesh. It uses your own body muscle for repair and gives virtually complete cure from inguinal hernia problem. An undetached strip of the external oblique aponeurosis is stitched on the weak area between the muscle arch and the inguinal ligament to form a new, strong and physiologically dynamic posterior wall that gives protection and prevents re-herniation. Normally patient goes home in a day after surgery and can drive car and go to office in 3-4 days time. This "Dr.Desarda's hernia repair" is now followed in many countries all over the world. We are surprised to see the enquiries from many patients in the developed countries asking for this repair in their country. This is because this operation does not use any foreign body like mesh for repair and therefore there are no complications that are seen in mesh repairs. A visit to Topix or other hernia forums show thousands of posts showing sufferings of many patients due to mesh repairs. But still why surgeons from developed countries are interested in mesh repairs is a big question for us. Please visit our website for more details: http://herniasurgery.tripod.com Our cell number: +91 9373322178

Vaccines are extremely safe. Adverse reactions are uncommon. The most common reaction is pain and swelling at the vaccine site, which is easily treated, and has no longterm problems. An allergic reaction to vaccines are rare. Dr. Michael Davis dispells this and other vaccine myths, including myths about autism and vaccines.

laparoscopic cornuotomy using a temporary tourniquet suture and diluted vasopressin injection in interstitial pregnancy video

Combination of Spinal and Epidural for Obstetric analgesia

A great video discussing ultrasound guidance of central venous catheter placement