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After a bad fall, a patient suffering from spinal fusion seeks help from a DMC Neurosurgery specialist.
~ Detroit Medical Center

Injuries and certain medical conditions can result in bleeding. This can trigger anxiety and fear, but bleeding has a healing purpose. Still, you need to understand how to treat common bleeding incidents, like cuts and bloody noses, as well as when to seek medical help.

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Epilepsy surgery is reserved for people whose seizures are not well controlled by seizure medicines. This situation is sometimes called being "medically refractory" or "drug resistant." In children, the definition of medically refractory is even more individualized to the specific child's situation. Surgery may be considered for some children after weeks to months of treatment with seizure medicines.

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TPE removes large-molecular-weight substances such as harmful antibodies from the plasma. It is usually carried out using an automated blood cell separator to ensure fluid balance and maintain a normal plasma volume. This may require the insertion of a femoral or jugular line to allow adequate blood flow. Typically, 30–40 mL/kg of plasma (1–1.5 plasma volumes) are removed at each procedure and replaced with isotonic 4.5 or 5.0% human albumin solution (some services substitute 25–50% of replacement volume with 0.9% saline). Exchange with fresh frozen plasma (FFP) is reserved for the replacement of ADAMTS13 in thrombotic thrombocytopenic purpura (see below) or to replace clotting factors. A one plasma volume exchange removes about 66% of an intravascular constituent and a two plasma volume exchange approximately 85%. TPE is normally combined with disease modifying treatment, such as immunosuppressive drugs, for the underlying condition.

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