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Nonalcoholic fatty liver disease is an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. As the name implies, the main characteristic of nonalcoholic fatty liver disease is too much fat stored in liver cells. Nonalcoholic steatohepatitis, a potentially serious form of the disease, is marked by liver inflammation, which may progress to scarring and irreversible damage. This damage is similar to the damage caused by heavy alcohol use. At its most severe, nonalcoholic steatohepatitis can progress to cirrhosis and liver failure Nonalcoholic fatty liver disease is increasingly common around the world, especially in Western nations. In the United States, it is the most common form of chronic liver disease, affecting an estimated 80 to 100 million people. Nonalcoholic fatty liver disease occurs in every age group but especially in people in their 40s and 50s who are at high risk of heart disease because of such risk factors as obesity and type 2 diabetes. The condition is also closely linked to metabolic syndrome, which is a cluster of abnormalities including increased abdominal fat, poor ability to use the hormone insulin, high blood pressure and high blood levels of triglycerides, a type of fat. Nonalcoholic fatty liver disease care at Mayo Clinic Request an Appointment at Mayo Clinic Symptoms & causes Aug. 23, 2016 Print Share on: Facebook Twitter References Related Magnetic resonance elastography Nonalcoholic fatty liver disease Overview Symptoms & causes Diagnosis & treatment Diagnosis Treatment Departments & specialties Expertise & rankings Locations, travel & lodging Clinical trials Research Costs & insurance Preparing for your appointment Self-management More about In-Depth Multimedia Resources News from Mayo Clinic Advertisement
Lipid-Lowering Agents HMG-CoA reductase inhibitors (statins) These agents inhibit the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase. Note the following: Low-density lipoprotein (LDL) reduction of 25%-60% Examples include Atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin Contraindications include hypersensitivity, active liver disease, pregnancy, lactation, coadministration with strong CYP3A4 inhibitors (selected statins) Vitamin B3 Vitamin B3 inhibits very-low-density lipoprotein (VLDL) synthesis. Note the following: LDL reduction of 10% High-density lipoprotein (HDL) increase of 20% Example includes Niacin (nicotinic acid) Contraindications include hypersensitivity, liver disease, active peptic ulcer, severe hypotension, arterial bleeding Fibrates Fibrates enhance lipoprotein lipase, resulting in increased VLDL catabolism, fatty acid oxidation, and triglycerides elimination. They decrease hepatic extraction of free fatty acids. Note the following: LDL reduction of 15% Triglyceride reduction of 35% Examples include Gemfibrozil, fenofibrate, fenofibrate (micronized), fenofibric acid Contraindications include active liver disease, renal disease, primary biliary cirrhosis, gallbladder disease 2-Azetidiones These agents inhibit sterol transporter at brush border and, consequently, intestinal absorption of cholesterol. LDL reduction of 15% Example includes Ezetimibe Contraindications include hypersensitivity, coadministration with statins (if active liver disease) Bile acid sequestrants These agents lower cholesterol and LDL via bile duct sequestration. Note the following: LDL reduction of 15% Examples include Cholestyramine, colesevelam, colestipol Contraindications include biliary/bowel obstruction, serum triglycerides >300-500 mg/dL, history of hypertriglyceridemia-induced pancreatitis
Shut the front door: Scientists have finally found the perfect breasts. No, they weren't hiding in the Amazon or roving solo across the Sahara (although we have no doubt there are women in both the Amazon and the Sahara who have magnificent mammaries); it turns out these perfect breasts were hiding in a plastic surgeon's office this whole time! Now, before you get all worked up, the American Society of Plastic Surgeons (ASPS) would like you to know that the super-fake looking plastic breasts of yore are not actually what people think are most attractive now. According to a study published in the Journal of Plastic and Reconstructive Surgery—which involved asking over 1,300 people to look at pictures of naked boobies and rank them by hotness (stop laughing, this is serious research!)—people preferred a more "real" and "normal" look from their silicone, with the ideal breast shape having a 45:55 ratio. People said the best chests have 45 percent of the fullness above the nipple line and 55 percent of the fullness below, in a slightly teardrop shape. Researchers noted this preference remained consistent across gender, racial, and ethnic groups with the 45:55 ratio favored by 87 percent of women in their 30s, 90 percent of men, and 94 percent of plastic surgeons.
Our Pain Center is the nation & leading Pain Center featuring award winning Pain Specialists. Our Pain Doctors are Harvard Trained and are experts in Facet Injections, Epidural, Knee Injection, Back Surgery, Knee Surgery, and Orthopedic Surgery.
Research from Mayo Clinic finds that half of elderly patients who start dialysis after age 75 will die within one year.
Lead study author and a health care delivery scholar with the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Dr. Bjorg Thorsteinsdottir says many elderly patients and their families feel that they have no choice but to start dialysis, with several expressing regret from having initiated therapy.
The findings were presented at the American Society of Nephrology's Kidney Week 2013 in Atlanta.
This is a 60 year man having large swelling of size 7cm x 5 cm behind neck for one year. Patient complained pain and tenderness over local area for 7 days and came to us.On examination punctum found in the centre of swelling and fluctuation positive.Infected sebaceous cyst diagnosis made. /nIncision and drainage surgery done under local anesthesia.all infected pultaceous material evacuated.Pus culture sent and antibiotics given as per sensitivity report./nPatient improved with daily dressing.
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In this video, I will walk you through a comprehensive rehab program for the most commonly injured knee ligament - the MCL.
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Intro (0:00)
Anatomy & Function (0:08)
Classification (1:11)
Treatment Options (1:46)
Bracing (3:30)
Rehab Overview (4:28)
Early Stage (5:27)
Mid-Stage(8:50)
Late Stage/Return to Sport (21:14)
Programming (22:13)
Summary (23:47)
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Disclaimer: The information presented is not intended as medical advice or to be a substitute for medical counseling but intended for entertainment purposes only. If you are experiencing pain, please seek the appropriate healthcare professional.
Knee replacement surgery advances are improving patients' experiences and outcomes. Knee surgery -- or even partial knee replacement -- is often the solution for advanced knee arthritis. Today you can regain significant mobility and flexibility after knee replacement thanks to advances in orthopedic surgery technology, materials and techniques. Knee replacement recovery times also have improved. This knee replacement surgery video covers what you can expect out of these knee joint replacement advances. Knee replacement surgery has been around for more than 30 years and is an incredibly successful operation. In the past the past, when a person had bad arthritis of the knee, they were pretty much out of luck other than taking aspirin. They'd be debilitated and limited in their activities. So, when a person has pain, stiffness, and their life is becoming restricted by that, that's when it's time to consider knee replacement. We always do non-surgical treatment first. When that doesn't work anymore, then it's time to consider knee replacement. About 500,000 a year are done, and most patients who have gone through this basically say that they wish they had done it sooner.
Dialysis services at UC San Diego Health: https://health.ucsd.edu/care/kidney/dialysis
UC San Diego Health Licensed Clinical Social Worker, Norma Reggev, discusses hemodialysis as a treatment option for failing kidneys with patient testimonials. Discussion includes In Center Hemodialysis and Home Hemodialysis.
0:00 - Hemodialysis
1:34 - When Should Dialysis Begin?
2:00 - What is Dialysis?
2:25 - How Hemodialysis Works
3:15 - In-Center Hemodialysis Considerations
3:42 - Patient Shares Their Experience With In-Center Hemodialysis
7:30 - Home Hemodialysis Considerations
8:35 - Patient Shares Their Experience With Home Hemodialysis
12:23 - Types of Vascular Access
A spermatocele (SPUR-muh-toe-seel) is an abnormal sac (cyst) that develops in the epididymis — the small, coiled tube located on the upper testicle that collects and transports sperm. Noncancerous and generally painless, a spermatocele usually is filled with milky or clear fluid that might contain sperm. The exact cause of spermatoceles is unknown but might be due to a blockage in one of the tubes that transports sperm. Spermatoceles, sometimes called spermatic cysts, are common. They typically don't reduce fertility or require treatment. If a spermatocele grows large enough to cause discomfort, your doctor might suggest surgery.