Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading to inhibition of DNA synthesis and inhibition of cellular replication. The mechanism involved in its activity against rheumatoid arthritis is not known.

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One of the most common knee injuries in contact and collision sports is a medial collateral ligament (MCL) injury. This is a ligament on the medial (side closest to the midline) side of your knee that provides stability against side-to-side stress to the knee. You might injure it by cutting maneuvers in sports like soccer or hockey. You can also suffer an MCL injury if another player hits you on the outside of your knee.

Please note: I don't respond to questions and requests for specific medical advice left in the comments to my videos. I receive too many to keep up (several hundred per week), and legally I can't offer specific medical advice to people who aren't my patients (see below). If you want to ask a question about a specific injury you have, leave it in the comments below, and I might answer it in an upcoming Ask Dr. Geier video. If you need more detailed information on your injury, go to my Resources page: https://www.drdavidgeier.com/resources/

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Unlike tears of the ACL, MCL injuries most often heal without surgery. You might need to wear a hinged knee brace for 2-6 weeks. The length of time you miss from sports or exercise varies depending on the location and severity of the injury.

In this video, I share my thoughts on the nature of an MCL injury, the diagnosis, the treatment options and return to sports.

Please remember, while I appreciate your questions, I cannot and will not offer specific medical advice by email, online, on my show, or in the comments at the end of these posts. My responses are meant to provide general medical information and education. Please consult your physician or health care provider for your specific medical concerns.

Upper gastrointestinal bleeding (sometimes upper GI, UGI bleed, Upper gastrointestinal hemorrhage, gastrorrhagia) refers to bleeding in the upper gastrointestinal tract, commonly defined as bleeding arising from the esophagus, stomach, or duodenum. In fact, the proportion of UGIB cases caused by peptic ulcer disease has declined, a phenomenon that is believed to be due to the use of proton pump inhibitors (PPIs) and H pylori therapy. Duodenal ulcers are more common than gastric ulcers, but the incidence of bleeding is identical for both.

An animation illustrating valvular heart surgery

Pioneer Plus IVUS Re-Entry Catheter plaque removal

Giant Swollen Leg Elephantiasis Filariasis

Formerly called toxemia, preeclampsia is a condition that pregnant women develop. It is marked by high blood pressure in women who have previously not experienced high blood pressure before. Preeclamptic women will have a high level of protein in their urine and often also have swelling in the feet, legs, and hands.

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Learn How to Suture a Banana

Ganglion Cyst Drained with BIG Needle

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Welcome to the world of Dr. Pimple Popper, the one and only Sandra Lee, MD! As a board certified dermatologist, skin cancer surgeon, and cosmetic surgeon, I am a highly sought-after expert in the field of dermatology.

On this channel, you'll find a treasure trove of videos that offer a window into my world.
Hopefully you'll learn about various skin conditions, hair and nail issues, and cutting-edge cosmetic surgery techniques. Whether you're struggling with blackheads, acne, cysts, warts, or looking for Botox, fillers, or liposuction, you'll find helpful advice and information here.

But this channel isn't just about skin care - it's about the amazing people I encounter every day. You'll get to know some of my incredible patients and their stories, and maybe even fall in love with dermatology just as much as I have!

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Infant Child Needle Selection and Insertion Technique Animation Video

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Robotically assisted heart surgery is a minimally invasive option most often used for mitral valve repair. Cleveland Clinic cardiothoracic surgeons explain how it works and what to expect.

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If you need heart bypass surgery, the procedure is pretty similar. A surgeon takes blood vessels from another part of your body to go around, or bypass, a blocked artery. The result is that more blood and oxygen can flow to your heart again. ... Bypass surgery is also known as coronary artery bypass grafting (CABG).Dec 12, 2015

Skin grafting is a type of medical grafting involving the transplantation of skin. The transplanted tissue is called a skin graft. Skin grafting is often used to treat: Extensive wounding or trauma Burns Areas of extensive skin loss due to infection such as necrotizing fasciitis or purpura fulminans Specific surgeries that may require skin grafts for healing to occur – most commonly removal of skin cancers. Skin grafts are often employed after serious injuries when some of the body’s skin is damaged. Surgical removal (excision or debridement) of the damaged skin is followed by skin grafting. The grafting serves two purposes: it can reduce the course of treatment needed (and time in the hospital), and it can improve the function and appearance of the area of the body which receives the skin graft. There are two types of skin grafts, the more common type is where a thin layer is removed from a healthy part of the body (the donor section), like peeling a potato, or a full thickness skin graft, which involves pitching and cutting skin away from the donor section. A full thickness skin graft is more risky, in terms of the body accepting the skin, yet it leaves only a scar line on the donor section, similar to a Cesarean section scar. For full thickness skin grafts, the donor section will often heal much more quickly than the injury and is less painful than a partial thickness skin graft.

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NG (Nasogastric) Tube Insertion Techniques (Nursing Skills)

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NG (Nasogastric) Tube Insertion Techniques (Nursing Skills)

In this video we’re going to show you the correct technique for insertion of an NG tube or Nasogastric tube). We’ll also give you a few tips and tricks we use. Of course, before you get started, make sure you’ve determined which nare is more patent and that the patient doesn’t have a deviated septum. Before you start, lay a towel across the patient’s chest – I’m telling you I’ve had patients throw up on me – this step is WORTH IT!! We love you guys! Go out and be your best selves today! And, as always, happy nursing!

Bookmarks:
0.05 Introduction to NG Tube Insertion techniques
0.25 Towel placement
0.32 Measuring NG tube length
1.04 Tape preparation
1.27 Give patient water
1.34 NG Tube lubrication
1.42 NG Tube insertion technique
2.25 Securing the NG tube
2.36 Checking placement/ aspiration
2.55 Assessing pH
3.08 Confirming placement
3.22 Waiting for abdominal X-ray
3.35 Supply clean-up
3.48 NG Tube insertion outro

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I talk about 5 Essential Skills you need as a nurse. These skills are timeless in the fat that you will always need to use them at some level. Of course specific skills are good to have as well but these skills are universal and can help you in other areas of life as well.

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#GIT#Abdominalexamination#AETCM

Bone tumors include abnormal healing of an injury, inherited conditions, radiation therapy. It can also be caused by bone cancer or another cancer that has spread to the bone from other parts of the body. A bone tumor may cause a painless mass. Some people have dull, aching pain. And in some cases, minor injury causes a fracture near the tumor. Treatments include surgery and radiation. Some noncancerous tumors go away without treatment