Sepsis is a potentially life-threatening complication of an infection. Sepsis occurs when chemicals released into the bloodstream to fight the infection trigger inflammatory responses throughout the body. This inflammation can trigger a cascade of changes that can damage multiple organ systems, causing them to fail. If sepsis progresses to septic shock, blood pressure drops dramatically, which may lead to death. Anyone can develop sepsis, but it's most common and most dangerous in older adults or those with weakened immune systems. Early treatment of sepsis, usually with antibiotics and large amounts of intravenous fluids, improves chances for survival. Symptoms & causes Symptoms Many doctors view sepsis as a three-stage syndrome, starting with sepsis and progressing through severe sepsis to septic shock. The goal is to treat sepsis during its early stage, before it becomes more dangerous. Sepsis To be diagnosed with sepsis, you must exhibit at least two of the following symptoms, plus a probable or confirmed infection: Body temperature above 101 F (38.3 C) or below 96.8 F (36 C) Heart rate higher than 90 beats a minute Respiratory rate higher than 20 breaths a minute Severe sepsis Your diagnosis will be upgraded to severe sepsis if you also exhibit at least one of the following signs and symptoms, which indicate an organ may be failing: Significantly decreased urine output Abrupt change in mental status Decrease in platelet count Difficulty breathing Abnormal heart pumping function Abdominal pain Septic shock To be diagnosed with septic shock, you must have the signs and symptoms of severe sepsis — plus extremely low blood pressure that doesn't adequately respond to simple fluid replacement. When to see a doctor Most often sepsis occurs in people who are hospitalized. People in the intensive care unit are especially vulnerable to developing infections, which can then lead to sepsis. If you get an infection or if you develop signs and symptoms of sepsis after surgery, hospitalization or an infection, seek medical care immediately. Causes While any type of infection — bacterial, viral or fungal — can lead to sepsis, the most likely varieties include: Pneumonia Abdominal infection Kidney infection Bloodstream infection (bacteremia) The incidence of sepsis appears to be increasing in the United States. The causes of this increase may include: Aging population. Americans are living longer, which is swelling the ranks of the highest risk age group — people older than 65. Drug-resistant bacteria. Many types of bacteria can resist the effects of antibiotics that once killed them. These antibiotic-resistant bacteria are often the root cause of the infections that trigger sepsis. Weakened immune systems. More Americans are living with weakened immune systems, caused by HIV, cancer treatments or transplant drugs. Risk factors Sepsis is more common and more dangerous if you: Are very young or very old Have a compromised immune system Are already very sick, often in a hospital's intensive care unit Have wounds or injuries, such as burns Have invasive devices, such as intravenous catheters or breathing tubes Complications Sepsis ranges from less to more severe. As sepsis worsens, blood flow to vital organs, such as your brain, heart and kidneys, becomes impaired. Sepsis can also cause blood clots to form in your organs and in your arms, legs, fingers and toes — leading to varying degrees of organ failure and tissue death (gangrene). Most people recover from mild sepsis, but the mortality rate for septic shock is nearly 50 percent. Also, an episode of severe sepsis may place you at higher risk of future infections.

Histology of Secretory Endometrium

Dialysis lecture 1. Dialysis Study: EXPERT NOTES for DHA, Bonent, CHT, B.Sc in Dialysis, Diploma in Dialysis https://amzn.eu/d/35Ui1kT

2. Dialysis Study : Q & A: MCQs, Fill in the blanks, True or False https://amzn.eu/d/gGn8u73

1. Dialysis Study :EXPERT NOTES for DHA, Bonent, CHT, B.Sc in Dialysis, Diploma in Dialysis, Naseha Helal.
https://play.google.com/store/....books/details?id=D_7

2. Dialysis Study: Q & A MCQ https://play.google.com/store/....books/details?id=T_3

Whatsapp
https://chat.whatsapp.com/DKCHbgsNwXS1wd7xI31tpr

Telegram
https://t.me/dialysislife PRINCIPLE OF dialysis
https://youtu.be/cfOm0aFmbe8

Dialysis machine alarms
https://youtu.be/-1A1INyDEOg

DDS dialysis disequilibrium syndrome
https://youtu.be/8AqVFiBOkIc

Peritoneal Dialysis
https://youtu.be/iHPPadGmsv0

Itching
https://youtu.be/T83Wm3HHU4M

What is CRRT
https://youtu.be/jPgFnoSEBMU

LVH
https://youtu.be/ZhFL3Z6LHeA

Sorbent dialysis
https://youtu.be/-rie5dC_FkY

RO Water
https://youtu.be/3jlEsK4Lg_I

Carbon filter RO water
https://youtu.be/mJrgtjNafQw

Hemoperfusion
https://youtu.be/UkbBm8rm9Ww

AV fistula or Dialysis fistula
https://youtu.be/uDbyfqCkCbo

Dialysis MCQ
https://youtu.be/zmOj0BL6jVY

AVF cannulation
https://youtu.be/PyqMcHA07zY

Complications of AV fistula
https://youtu.be/a_CXIvuOO_s

Blood clotting during Dialysis
https://youtu.be/9hYNepiO2o8

Muscle crapms
https://youtu.be/09s07Eiqr2k

Hepatitis C
https://youtu.be/qdNj_GhmnSE

Dialysis procedure
https://youtu.be/u1mGqXO5pzQ

Hypotension
https://youtu.be/4EVPmWTSyN8

Heparin free dialysis
https://youtu.be/rFqAn7HcWwM

Plasmapheresis
https://youtu.be/kbgsjjs9krg

Isolated ultrafiltration
https://youtu.be/xp5I5--uWb0

High flux dialyzer
https://youtu.be/gCNsErn1HHM

Urea and Creatinine
https://youtu.be/Id9AIySMQ6c

Practical RO water demo
https://youtu.be/2pXKGMDNS84

Sodium profiling
https://youtu.be/bE_DcBXNB5g

Peritoneal Dialysis
https://youtu.be/vtK6VZsi8AY

Air embolism
https://youtu.be/WJE-xqnQfd8

Dialysate
https://youtu.be/z_nb43bcWsM

How to stop Bleed from fistula
https://youtu.be/N_inLKPhPUc

Dialysis short form
https://youtu.be/3BqB-gODb5o

Dialyzer reprocessing
https://youtu.be/XelfkKsndlc

Dialysis catheter
https://youtu.be/V7y90m4xlv8

How to set KT/V
https://youtu.be/hWXjU8VTQdk

Mircera injection
https://youtu.be/STtd3I3EijA

Dialysis procedure
https://youtu.be/MIdhIgcKRZ8

Dialysis in snake bite poison
https://youtu.be/niA9RI38jyY

Uf profiling
https://youtu.be/wyjpFjD5Hi0

Heparin dose
https://youtu.be/kB56MkzHIQ0

Hyperkalemia
https://youtu.be/1rWWNlcAuio

Change bandages of leaking fistula
https://youtu.be/_0cebWWdjM8

AvF needle
https://youtu.be/GvUxbXxftTk

Polycystic kidney disease
https://youtu.be/IhsMbHFXZG8

Nephrotic syndrome
https://youtu.be/FEEOsIrXxV8

Diabetic nephropathy
https://youtu.be/v-FBIQ7MA4k

Hemodialysis permanent access
https://youtu.be/_YrwxwiR0f8

Sex and dialysis
https://youtu.be/vvl8UT8lK4k

Albumin and dialysis
https://youtu.be/yzG7yD45Nwg

The condition is caused by a blockage in the lymphatic system, part of the immune and circulatory systems. Lymphedema is most commonly caused by lymph node removal or damage due to cancer treatment. The main symptom is swelling in an arm or leg that may be accompanied by pain or discomfort. Exercise, wrapping, massage, and compression can help.

Ganglion cysts are noncancerous lumps that most commonly develop along the tendons or joints of your wrists or hands. They also may occur in the ankles and feet. Ganglion cysts are typically round or oval and are filled with a jellylike fluid. Small ganglion cysts can be pea-sized, while larger ones can be around an inch (2.5 centimeters) in diameter. Ganglion cysts can be painful if they press on a nearby nerve. Their location can sometimes interfere with joint movement. If your ganglion cyst is causing you problems, your doctor may suggest trying to drain the cyst with a needle. Removing the cyst surgically also is an option. But if you have no symptoms, no treatment is necessary. In many cases, the cysts go away on their own.

Always remember: safety first. (Warning: Graphic)

Rheumatoid Arthritis,physiology,pathology,clinincal features,manifestations and treatment

Aplastic anemia is a hematopoietic disorder caused due to T lymphocyte mediated destruction of stem cells resulting in pancytopenia with a cellular bone marrow and normal cell cytogenetics. The causes of aplastic anaemia may be inherited or acquired. The causes and the diagnostic approach, along with spectrum of severity of this disorder is discussed in this presentation. A detailed discussion of the management options, along with pharmacological therapy and supportive therapy in these cases is also discussed. The treatment options include, in addition to a stem cell transplant, anti-thymocyte globulin, cyclosporine, methyprednisolone and eltrombopag (for patients who have failed treatment on combined modality therapy with ATG and cyclosporine)

How a Clot Can Become a Pulmonary Embolism

Because the continuous supply of glucose is stopped after birth, the neonate develops hypoglycemia because of insufficient substrate. Stimulation of fetal insulin release by maternal hyperglycemia during labor significantly increases the risk of early hypoglycemia in these infants.

The Irish Thoracic Society speak about the importance of Exercise with Chronic or Acute Respiratory illnesses/ Diseases and respiratory distress

An excellent video demonstrating how a laparoscopy is performed to evaluate the uterus (note a small fibroid appearing as a bulge in the uterus), fallopian tubes and ovaries. Blue dye is injected into the uterus, entering the fallopian tubes and spilling from the end of the tubes into the abdominal cavity, confirming that both tubes are open

Microsoft built a watch that helps people with Parkinson

Multiple endocrine neoplasia type 2 (MEN2) is a hereditary condition associated with three primary types of tumors: medullary thyroid cancer, parathyroid tumors, and pheochromocytoma. MEN2 is classified into three subtypes based on clinical features. MEN2A, which affects 60% to 90% of MEN2 families Medullary thyroid cancer: 98% to 100% with MEN2A are affected Pheochromocytoma, a typically benign (noncancerous) tumor of the adrenal glands: 50% with MEN2A affected Parathyroid adenoma (benign tumor) or hyperplasia, meaning increased size, of the parathyroid gland: 5% to 10% with MEN2A affected MEN2B, which affects 5% of MEN2 families Medullary thyroid cancer: 98% to 100% with MEN2B affected Pheochromocytoma: 50% with MEN2B affected Mucosal neuromas, which is a benign tumor of nerve tissue on the tongue, lips and throughout the gastrointestinal tract: 95% to 98% affected Digestive problems caused by disordered nerves in the gastrointestinal tract: 75% to 90% affected Muscle, joint, and spinal problems: 95% affected Typical facial features, including swollen lips and thick eyelids: 75% to 90% affected Familial medullary thyroid cancer (FMTC), which affects 5% to 35% of MEN2 families Medullary thyroid carcinoma only Sources: Gagel RF, Marx SJ. “Multiple endocrine neoplasia.” Williams Textbook of Endocrinology, Chapter 40, 11th ed., Philadelphia, 2008, and Eng C, Clayton D, et al. Grubbs EG, Gagel RF. My, How Things Have Changed in Multiple Endocrine Neoplasia Type 2A! J Clin Endocrinol Metab 100(7):2532-5, 7/2015. PMID: 26151398. What causes MEN2? MEN2 is a genetic condition. This means that the cancer risk and other features of MEN2 can be passed from generation to generation in a family. The gene associated with MEN2 is called RET. A mutation (alteration) in the RET gene gives a person an increased risk of developing medullary thyroid cancer and other tumors associated with MEN2.

A parasitic twin (also known as an asymmetrical or unequal conjoined twin) is the result of the processes that produce vanishing twins and conjoined twins, and may represent a continuum between the two. Parasitic twins occur when a twin embryo begins developing in utero, but the pair does not fully separate, and one embryo maintains dominant development at the expense of the other. Unlike conjoined twins, one ceases development during gestation and is vestigial to a mostly fully-formed, otherwise healthy individual twin. The undeveloped twin is defined as parasitic, rather than conjoined, because it is incompletely formed or wholly dependent on the body functions of the complete fetus. The independent twin is called the autosite.

Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. No one is sure what causes autoimmune diseases. They do tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases. There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting a diagnosis can be frustrating and stressful. Often, the first symptoms are fatigue, muscle aches and a low fever. The classic sign of an autoimmune disease is inflammation, which can cause redness, heat, pain and swelling. The diseases may also have flare-ups, when they get worse, and remissions, when symptoms get better or disappear. Treatment depends on the disease, but in most cases one important goal is to reduce inflammation. Sometimes doctors prescribe corticosteroids or other drugs that reduce your immune response.

A meningioma is a tumor that arises from the meninges — the membranes that surround your brain and spinal cord. Most meningiomas are noncancerous (benign), though rarely a meningioma may be cancerous (malignant). Some meningiomas are classified as atypical, meaning they're neither benign nor malignant but, rather, something in between.

New Treatment for sinusitis. Yamik procedure

Urinary Bladder Medical Exam