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While in residency, Marc Pelletier, MD, helped in a bypass surgery and knew it was the field in which he would excel. Watch as the Chief of Cardiac Surgery for University Hospitals Harrington Heart & Vascular Institute in Cleveland, Ohio explains, in detail, what happens in preparation for heart surgery, in the operating room and the feeling he experiences after surgery.
How does a heart-lung machine work? What is 'efficiency of motion'? These questions and more are answered in this compelling, dramatic look at heart surgery.
To learn more about heart surgery at University Hospitals: https://www.uhhospitals.org/fo....r-clinicians/special
University Hospitals is one of the nation’s leading health care systems, providing patient-centered care that meets the highest standards for quality and patient safety and have received numerous awards and recognitions from some of the most prestigious institutions in the country for our leadership and exceptional patient outcomes. As an accountable care organization, we foster long-term patient-provider relationships that help promote preventive care, increase wellness and healthy behaviors, decrease emergency episodes, and prevent hospitalizations. To learn more: https://www.uhhospitals.org
Retinitis pigmentosa is a rare, inherited degenerative eye disease that causes severe vision impairment. Symptoms often begin in childhood. They include decreased vision at night or in low light and loss of side vision (tunnel vision). There's no effective treatment for this condition. Wearing sunglasses may help protect remaining vision.
The Spirotome belongs to the Direct & Frontal type of biopsy systems for taking large core biopsy from virtually every soft tissue in the body. The FDA has approved 13 applications. This video shows how easy it is to take a large core from a thoracic wall tumor mass. The size and quality of the sample allows quantitative molecular biology.
This video will cover, in detail, the motor, sensory, reflect components of a neurological examination.
This video is created for the UBC Medicine Neurology Clinical Skills curriculum as part of MEDD 419 FLEX projects.
Filmed, written, and directed by:
John Liu
Vincent Soh
Chris Calvin
Kashi (Siyoung) Lee
Kero (Yue) Yuen
Ge Shi
Doctor - Dr. Jason Valerio (Department of Neurology, UBC)
Supervised by:
Dr. Alex Henri-Bhargava (Department of Neurology, UBC)
Zac Rothman (UBC FOM Digital Solutions: Ed Tech)
Edited by:
Stephen Gillis
Produced by UBC FOM Digital Solutions EdTech team facilitates innovation by UBC Medicine learners and faculty.
Website: https://education.med.ubc.ca/
Subscribe: https://www.youtube.com/ubcmed....vid?sub_confirmation
UBCMLN Podcast Network: https://tinyurl.com/ubcmedicinelearningnetwork
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The Southern Medical Program and the Okanagan Academic Campus of the University of British Columbia are situated on the territory of the Syilx Okanagan Nation.
The Northern Medical Program and the University of Northern BC are situated on the traditional territory of the Lheidli T’enneh, part of the Dakelh (Carrier) First Nations.
With respect the Lekwungen peoples on whose traditional territory the Island Medical Program and the University of Victoria stand and the Songhees, Esquimalt and WSÁNEĆ peoples whose historical relationships with the land continue to this day.
We acknowledge our traditional hosts and honour their welcome and graciousness to the students who seek knowledge here.
© UBC Faculty of Medicine
All rights reserved. Reproduction and distribution of this presentation without written permission from UBC Faculty of Medicine is strictly prohibited.
Selective immunoglobulin A deficiency (SIgAD) is a primary immunodeficiency disease and is the most common of the primary antibody deficiencies.[1] Total immunoglobulin A deficiency (IgAD) is defined as an undetectable serum immunoglobulin A (IgA) level at a value < 5 mg/dL (0.05 g/L) in humans. Partial IgAD refers to detectable but decreased IgA levels that are more than 2 standard deviations below normal age-adjusted means.[2, 3] IgAD is commonly associated with normal B lymphocytes in peripheral blood, normal CD4+ and CD8+ T cells, and, usually, normal neutrophil and lymphocyte counts. Anti-IgA autoantibodies of the IgG and/or IgE isotype may be present. Peripheral blood may also be affected by autoimmune cytopenias, eg, autoimmune thrombocytopenia,[4, 5] and patients may have other autoimmune phenomena. IgA was first identified by Graber and Williams in 1952; ten years later, the first patients with IgAD were described. IgAD is a heterogeneous disorder, and the results of intensive study are beginning to elucidate genetic loci and molecular pathogenesis that contribute to various subtypes of this disorder. Several lines of evidence suggest that, in many cases, IgAD and common variable immunodeficiency (CVID) have a common pathogenesis, which is discussed further in Pathophysiology. Other data indicate different genetic risk factors. Family studies show variable inheritance patterns. Familial inheritance of IgAD occurs in approximately 20% of cases,[6] and, within families, IgAD and CVID are associated.[7, 8] Many IgAD patients are asymptomatic (ie, "normal" blood donors) and are identified by finding a laboratory abnormality, without any apparent associated clinical disease. Some patients with IgAD may have the following associated conditions: (1) deficits in one or more immunoglobulin G (IgG) subclasses (this accounts for 20-30% of IgA-deficient patients, many of whom may have total IgG levels within the normal range) or (2) a deficient antibody response to pneumococcal immunization (specific polysaccharide antibody deficiency [SPAD]). Some patients with IgAD later develop CVID, and family members of patients with CVID may have only selective IgAD. Characterization of the receptor for the transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI), encoded by the gene TNFRSF13B ( tumor necrosis factor receptor superfamily member 13B), suggests that people with the C104, A181E, and ins204A variants may be at risk for IgAD that progresses to CVID.[9] Primary IgAD is permanent, and below-normal levels have been noted to remain static and persist after 20 years of observation.[10] A recent report documents a rare case of reversion.[11] Environmental factors such as drugs or infections can cause IgAD, but this form is reversible in more than half the cases (see Causes). Although individuals with IgAD have largely been considered healthy, recent studies indicate a higher rate of symptoms. A 20-year follow-up study that compared 204 healthy blood donors with incidentally identified IgAD to 237 healthy subjects with normal IgA levels demonstrated that 80% of IgAD donors and 50% of control subjects had episodes of infections, drug allergy, or autoimmune or atopic disease. Severe respiratory tract infections occurred in 26% of IgAD subjects, in 24% of subjects with decreased IgA levels, and in 8% of control subjects; however, the incidence of life-threatening infections was not increased. IgAD is more common in adult patients with chronic lung disease than in healthy age-matched control subjects.[12] Patients with IgAD are at some increased risk of developing severe reactions after receiving blood products.[13, 14, 15] IgG anti-IgA antibodies may cause severe transfusion reactions if patients with IgAD are given whole blood; therefore, IgA-poor blood or washed red cells are preferred for those patients. IgA-deficient patients with immunoglobulin E (IgE)–class anti-IgA antibodies are at risk for anaphylaxis if they receive blood or intravenous immunoglobulin, but this situation is extremely rare. Individuals with such an unusual profile should receive only low IgA intravenous immunoglobulin preparations. However, caution must be used when administering IGIV to patients with IgAD if their anti-IgA status is unknown. A history devoid of previous blood product administration does not exclude the possibility of anti-IgA antibodies or adverse reactions. Fortunately, appropriate precautions can significantly reduce morbidity (see Treatment). Blood banks can use a simple ELISA screening approach to establish an IgAD blood donor poo
The majority of all headaches are tension related headaches. The blockage of blood circulation along with contraction/shortening of muscles is what causes this condition. This simple technique can take away most tension related headaches in seconds.
Massive bone defects (>8 cm) will not unite without an additional intervention. They require a predictable, durable, and efficient method to regrow bone. The Ilizarov method of tension stress, or distraction osteogenesis, first involves a low-energy osteotomy1 - 5. The bone segments are then pulled apart, most often using an external device at a specific rate and rhythm (distraction phase), after which the newly formed bone (the regenerate) requires time for consolidation. The consolidation phase is variable and usually requires a substantially greater amount of time before the external device can be removed. Our technique of tibial bone transport over an intramedullary nail using cable and pulleys combines internal and external fixation, allowing the external fixator to be removed at the end of the distraction phase. This increases the efficiency of limb reconstruction and decreases the external-fixator-associated complications.
Symptoms of serotonin syndrome include a classic triad of mental status changes (eg, anxiety, delirium, confusion, restlessness), autonomic dysregulation (eg, diaphoresis, tachycardia, hypertension, hyperthermia, diarrhea, mydriasis), and neuromuscular hyperactivity (eg, hyperreflexia, tremor, rigidity, myoclonus, ocular clonus). Serotonin syndrome is clinically diagnosed and laboratory tests are used to rule out other etiologies. It usually occurs due to inadvertent interactions between drugs, therapeutic use of multiple serotonergic agents, or serotonergic medication overdose. Treatment involves discontinuation of serotonergic drugs, supportive measures, and sedation with benzodiazepines. In severe cases, a serotonin antagonist (cyproheptadine) may be used.
What are the disadvantages of male condoms? a moderately high failure rate when used improperly or inconsistently. the potential for diminished sensation. skin irritation, such as contact dermatitis, due to latex sensitivity or allergy. allergic reactions to spermicides, lubes, scents, and other chemicals in the condoms.
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Intramuscular Injection Techniques (Nursing Skills)
In this video, we’re going to look at proper administration techniques for intramuscular medication administration. Of course, always follow your 5 rights and calculate the correct volume for administration. We love you guys! Go out and be your best selves today! And, as always, happy nursing!
Bookmarks:
0.05 Introduction to Intramuscular injections
0.16 site and needle selection
0.35 site sterilization
0.43 Z track method
0.58 needle insertion
1.10 medication injection
1.14 needle removal
1.25 bandaging and needle disposal
1.30 documentation and patient monitoring
1.35 Outro
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Chalazions are extremely common, and having a sound surgical technique to drain a chalazion is a fundamental in general ophthalmology and oculoplastic surgery. I believe one of the biggest downfalls in treating chalazions is inadequate local anesthetic. Please that both the outer and inner surface to the eyelid need to receive local anesthesia to make the patient totally comfortable. It is important to be careful in delivering the local anesthetic and making sure you have control of the head position, and the position of your needle is bent to minimize any possibility of contact with the globe.
Diabetic ketoacidosis is an acute complication of uncontrolled hyperglycaemia characterised by high anion gap metabolic acidosis, dehydration and other metabolic abnormalities. Upto half of patients with Type 1 diabetes mellitus may have DKA. The incidence in T2DM is also rising. Precipitants include acute illness such as myocardial infarction, trauma and infection. Paitents of diabetic ketoacidosis may present with vomiting, pain abdomen and lethargy. Mental obtundation may also be present. Management of diabetic ketoacidosis revolves around administration of IV normal saline, insulin, replacement of potassium with frequent monitoring of sugars and electrolytes.
This video documents the experience of one of our Mommy Makeover patients. She is 39 years old, 5’4” tall, and of average weight. Following the birth of her twins, she wanted to improve her abdominal wall contour and correct the lack of shape and firmness in her breasts.