What Is It? Your wisdom teeth (third molars) usually start to erupt (enter your mouth) during the late teen years. Sometimes, there's not enough room for them. They may come into your mouth partially or not at all. Partial eruption of a wisdom tooth can create a flap of gum tissue next to the tooth. The flap can trap bits of food and debris. It can turn into a hotbed for bacteria. It's called pericoronitis if the tissue around the tooth becomes inflamed. Pericoronitis also can occur around a wisdom tooth that is still completely under the gums. Symptoms Symptoms include: Painful, swollen gum tissue in the area of the affected tooth. It can be difficult to bite down comfortably without catching the swollen tissue between your teeth. A bad smell or taste in the mouth Discharge of pus from the gum near the tooth More serious symptoms include: Swollen lymph nodes under your chin (the submandibular nodes) Muscle spasms in the jaw Swelling on the affected side of the face Diagnosis Usually, someone with pericoronitis goes to the dentist, complaining of pain in the area of the back tooth. Pericoronitis is diagnosed during the clinical exam. Your dentist will see inflamed gum tissue in the area of the unerupted or partly erupted wisdom tooth. The gums may be red, swollen or draining fluid or pus. Expected Duration Pericoronitis can be managed with antibiotics and warm salt water rinses. It goes away in about one week. However, it can return. This is likely to happen if the tooth does not completely enter the mouth and food and bacteria keep building up under the gum. Prevention You can help to prevent pericoronitis by brushing any erupting wisdom tooth and flossing around it. This will help make sure that food and bacteria do not build up under the gums. However, sometimes these steps do not work. If pericoronitis returns, you may need to have the flap of gum tissue removed. In some cases, the flap of tissue grows back and the wisdom tooth will need to be extracted. Treatment Pericoronitis can be tricky to treat. That's because the flap of gum tissue won't go away until the wisdom tooth emerges naturally, the tissue is removed or the tooth is removed. Your dentist will clean the area thoroughly by rinsing under the flap with water to remove bits of food and pus. Your dentist also may need to remove damaged tissue. If the area is infected, you'll most likely be given antibiotics. Your dentist will explain how to keep the area clean, which is the best way to prevent the problem from returning. This usually involves brushing and flossing daily and rinsing your mouth with water several times a day. These steps will help to prevent food from getting stuck under the gum flap. In some cases, your dentist may suggest removing the erupting tooth. Or the dentist may want to remove the tooth above it, which bites down on the gum below. If your dentist thinks the tooth may erupt fully into the mouth without problems, he or she may leave it alone. However, if pericoronitis comes back, the tooth may be extracted. Pericoronitis that causes symptoms should be treated as soon as possible. If it is not, the infection can spread to other areas of your mouth. The most severe cases are treated in a hospital. They sometimes require intravenous antibiotics and surgery. When To Call a Professional If you have symptoms of pericoronitis, make an appointment to see your dentist. If your wisdom teeth are coming in, visit your dentist at least twice a year for regular checkups. During those visits, the dentist can check on the progress of your wisdom teeth. Prognosis Pericoronitis does not cause any long-term effects. If the affected tooth is removed or erupts fully into the mouth, the condition cannot return.

Vaginal discharge serves an important housekeeping function in the female reproductive system. Fluid made by glands inside the vagina and cervix carries away dead cells and bacteria. This keeps the vagina clean and helps prevent infection. Most of the time, vaginal discharge is perfectly normal. The amount can vary, as can odor and hue (its color can range from clear to a milky white-ish), depending on the time in your menstrual cycle. For example, there will be more discharge if you are ovulating, breastfeeding, or are sexually aroused. The smell may be different if you are pregnant or you haven't been diligent about your personal hygiene. None of those changes is cause for alarm. However, if the color, smell, or consistency seems significantly unusual, especially if it accompanied by vaginal itching or burning, you could be noticing an infection or other condition. What causes abnormal discharge? Any change in the vagina's balance of normal bacteria can affect the smell, color, or discharge texture. These are a few of the things that can upset that balance:

Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm. Digoxin is also used to treat atrial fibrillation, a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).

Central Venous Catheter Placement & Pulmonary Artery Catheter Video

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology)

Topics discussed:

Epidermis:
Layers of epidermis: 0:10
Melanocytes vs Keratinocytes: 5:16
Langerhans cells: 10:10 & 33:30 & 57:30

Dermis:
Papillary and reticular dermis: 11:50
Three types of white empty spaces on a slide: vessels, glands/ducts/cysts, or artifact: 15:25
Blood vessels & nerves: 18:24 & 48:50 & 58:59
Arrector pili & other dermal smooth muscle: 20:00

Adnexal:
Sebaceous gland: 21:10
Hair follicle 23:14
Eccrine sweat glands and ducts 24:45 & 50:00
Gland/duct vs blood vessel 27:20 & 48:50
Apocrine glands: this video https://kikoxp.com/posts/7837 (at 12:30)
Acrosyringium: this video https://kikoxp.com/posts/7837 (at 10:00)

Three types of pink bundles: smooth muscle, nerve, dense connective tissue: 27:50

Acral skin (palm sole) with contact dermatitis 29:37
Parakeratosis 30:00
Perivascular lymphocytes 30:40
Eosinophils vs neutrophils 31:20
Spongiosis with desmosome keratinocyte spines 32:10
Spongiotic vesicles with Langerhans cells 33:30
Normal acral skin (palm & sole) with stratum lucidum 34:20
Normal glomus body/apparatus (canal of Sucquet-Hoyer) 35:40
Nerve 36:46 & 51:50
Adipose tissue (white fat cells) in subcutis with Lochkern 37:55
Normal scalp skin with large anagen hair follicles: 39:30
Hair follicle anatomy (bulb/matrix, inner root sheath, outer root sheath, hair shaft, isthmus, infundibulum): 40:55 (labeled images):
https://kikoxp.com/posts/3661 & https://kikoxp.com/posts/7899
Pacinian corpuscle 50:40
Meissner corpuscle 1:02:28

Dense regular connective tissue (Fascia/Tendon/Ligament) vs Smooth Muscle 53:00

Basic Normal Skin Immunohistochemistry:
-cytokeratin in epidermis: 55:33
-S100 in melanocytes and Langerhans cells and adipocytes: 57:30
-Desmin in smooth muscle (arrector pili and blood vessels): 58:59
-CD31 in endothelial cells of blood vessels: 59:33
-SOX-10 in melanocytes: 1:00:40

Digit/Finger/Toe histology (amputation for subungual acral melanoma) 1:04:10 & 1:08:30
-bone 1:05:40
-glomus body 1:05:15
-tendon/ligament 1:06:10
-artery 1:06:58
-fingernail/toenail 1:08:54
-acrosyringium 1:10:45

Solar elastosis (what wrinkles look like microscopically!) 1:11:50

Other videos you might like:
Tendon vs Nerve Histology Made Simple with the Ramen Noodle Sign (of Fulton) video: https://kikoxp.com/posts/4466
Melanocytes vs Keratinocytes made easy video: https://kikoxp.com/posts/3802
Blood Vessel vs Gland vs Artifact Made Easy video: https://kikoxp.com/posts/4808

The basic normal structures of the skin discussed and described by a dermatopathologist. This material is intended for use by medical students, junior pathology or dermatology residents, or for anyone else studying normal human histology. Special thanks to two of my medical students at UAMS for helping make this video possible. Miki Lindsey convinced me that I really needed to sit down and record this video. Akash Patel took time to edit the video and make it ready for YouTube. My sincere thanks to both of them for helping me overcome procrastination.

Huge thanks to Abigail Cline, a medical student at Medical College of Georgia, for volunteering to type a transcript of this ENTIRE video (over 14,000 words!) so that I could provide closed caption subtitles for those with hearing impairments and for those who may need assistance in understanding spoken English (particularly given how quickly I speak!). You can access a text version of her transcript of my video here: https://kikoxp.com/posts/5390

Correction - I made a mistake in the video. I said that sebaceous gland secretions are turned into smelly substances by bacteria and that this makes body odor. That is incorrect. That is actually true of APOCRINE gland secretions not sebaceous secretions.

Also, in the past I used "keratinocyte" and "squamous cell" interchangeably (this is because in dermatopathology, we see and talk about squamous cell carcinomas all the time, and those tumors are composed of keratinocytes). But technically, in normal skin histology, "squamous cell" refers only to the flattened keratinocytes in the superficial epidermis. Thankfully, a histology PhD colleague pointed this out to me and corrected my lazy nomenclature!

Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB ‬

This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.

Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.

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It sounds like you're questioning whether or not your water may have broken, and this can actually be a hard thing for a lot of women to tell. Usually if your water breaks, it's just a trickle of fluid, and you're afraid to admit it to anyone because you think you peed your pants. And it is normal to pee your pants when you're pregnant because the bladder is right below the uterus, and if the baby moves just right, it might kick out a little bit of urine. So if you feel a trickle or a little tiny gush of fluid, what you want to do is put a pad or a pantie-liner on after going to the bathroom and emptying your bladder, and wait an hour and see if fluid continues to come out. And if it does, then you're not having bladder leakage issues - your water is probably broken.

- elbow dislocations in children are a relatively uncommon; - peak incidence occurs in adolescence between 11-15 years. - posterior dislocations are most common type; - posterior dislocation usually results from fall on outstretched hand w/ forarm supinated & elbow extended or partially flexed; - coronoid process, which nl resists posterior displacement of ulna, is relatively small in children; - anterior capsule of elbow joint is torn by force of the impact transmitted upward thru the ulna and radius

Vacuum Extraction Birth video

Syringomyelia (sih-ring-go-my-E-lee-uh) is the development of a fluid-filled cyst (syrinx) within your spinal cord. Over time, the cyst may enlarge, damaging your spinal cord and causing pain, weakness and stiffness, among other symptoms. Syringomyelia has several possible causes, though the majority of cases are associated with a condition in which brain tissue protrudes into your spinal canal (Chiari malformation). Other causes of syringomyelia include spinal cord tumors, spinal cord injuries and damage caused by inflammation around your spinal cord. If syringomyelia isn't causing any problems, monitoring the condition may be all that's necessary. But if you're bothered by symptoms, you may need surgery.

This video may contain images of a medical doctor providing emergency care for a patient.

The pathobiology of MM is complex and the root underlying cause of myeloma is the multistep genetic changes in the postgerminal center B cell. In addition, the bone marrow microenvironment plays a crucial role.[2] The interaction between myeloma cells and the microenvironment is mediated through adhesive interactions via cell-surface receptors, paracrine loops involving several cytokines, such as IL-6, VEGF and IL-10, and suppression of cell-mediated immunity.[2–4] IMiDs modulate many of these interactions leading to decreased myeloma cell growth and survival. Thalidomide was the first IMiD introduced to treat MM. It was initially synthesized in Germany in the late 1950s to treat insomnia and morning sickness. It was withdrawn from the market in 1961 because of its teratogenic effects. Its immunomodulatory properties were realized when it was observed to improve erythema nodosum leprosum, a painful immunologic reaction of leprosy, leading to its approval by the FDA in 1998 with tight prescribing and marketing regulations. Subsequent research showed the diverse mechanism of action of thalidomide including its immunomodulatory effect by inhibition of de novo IgM antibody synthesis,[5] modulation of the T-cell subset by increasing the T-helper cells, inhibitory effects on the TNF-α and antiangiogenic activity leading to its use in MM. Significantly higher response rates in combination with dexamethasone led to its approval in the treatment of newly diagnosed MM in 2006. Lenalidomide, a second-generation IMiD, was developed from the structural backbone of the thalidomide molecule by the addition of an amino group (NH2-) at position 4 of the phthaloyl ring and removal of the carbonyl group (C = O) of the 4-amino-substituted phthaloyl ring (Table 1).[6] In addition to immunomodulatory effects, other mechanisms of action have been described such as direct cytotoxicity via induction of apoptosis, inhibition of cell adhesion molecules and inhibition of growth signals that promote bone marrow angiogenesis

Histological features and cellular biology of exocrine glands. This video is a part of our Histology Video Course (https://youtube.com/playlist?l....ist=PLnr1l7WuQdDynxT

Additional YouTube Content
Biochemistry videos: https://youtube.com/playlist?l....ist=PLnr1l7WuQdDzCUC
Anatomy Videos: https://youtube.com/playlist?l....ist=PLnr1l7WuQdDz2dK
DaVinci Cases Videos: https://youtube.com/playlist?l....ist=PLnr1l7WuQdDyJUl
The DaVinci Hour Podcast: https://youtube.com/playlist?l....ist=PLnr1l7WuQdDwSm9

DaVinci Academy Website: https://www.dviacademy.com/

Triplet C-section

Computed tomography (CT)-guided transthoracic needle biopsy is a well-established, minimally invasive diagnostic tool for pulmonary lesions. Few large studies have been conducted on the diagnostic performance and adequacy for molecular testing of transthoracic core needle biopsy (TCNB) for small pulmonary lesions.

Constrictive pericarditis is the result of scarring and consequent loss of the normal elasticity of the pericardial sac. This leads to impairment of ventricular filling in mid and late diastole. As a result, the majority of ventricular filling occurs rapidly in early diastole and the ventricular volume does not increase after the end of the early filling period. Restrictive cardiomyopathy is characterized by a nondilated rigid ventricle, resulting in severe diastolic dysfunction and restrictive filling that produces hemodynamic changes similar to those in constrictive pericarditis. Constrictive pericarditis and restrictive cardiomyopathy both lead to diastolic heart failure with normal (or near normal) systolic function, and characteristically abnormal ventricular filling that results in similar clinical and hemodynamic features. However, because of their markedly different treatments, differentiating between the two conditions is critical. In some patients, the correct diagnosis may be readily suggested from the history or routine diagnostic testing. In others, however, this differentiation cannot be diagnosed before biopsy or even surgical exploration.

From UW Health's Neurosurgery Program: Learn more about the individual steps in the DBS surgery procedure. Visit uwhealth.org/dbs

Septic arthritis is also known as infectious arthritis, and is usually caused by bacteria, or fungus. The condition is an inflammation of a joint that's caused by infection. Typically, septic arthritis affects one large joint in the body, such as the knee or hip. Less frequently, septic arthritis can affect multiple joints

Breast implants do not last forever, and during its lifetime, it may rupture. Dr. Linder, Beverly Hills breast surgeon specialist, breaks down how removing breast implants works. To learn more about Dr. Stuart Linder and his expertise, Visit: www.drlinder.com

Check out our new website http://www.evanshealthlab.com/
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Dr. Mike Evans is founder of the Health Design Lab at the Li Ka Shing Knowledge Institute, an Associate Professor of Family Medicine and Public Health at the University of Toronto, and a staff physician at St. Michael's Hospital.

Written and Narrated by Dr. Mike Evans
Executive Producer, Dr. Mike Evans
Illustrations by Liisa Sorsa
Produced, Directed, and Photographed by Nick De Pencier
Editor, David Schmidt
Story/Graphic Facilitator, Disa Kauk
Production Assistant, Chris Niesing
Director of Operations, Mike Heinrich

©2014 Michael Evans and Reframe Health Films Inc.

Eosinophilic granulomatosis with polyangiitis (EGPA; also known as Churg-Strauss syndrome [CSS] or allergic granulomatosis) is a rare autoimmune condition that causes inflammation of small and medium-sized blood vessels (vasculitis) in persons with a history of airway allergic hypersensitivity (atopy).