Lipid-Lowering Agents HMG-CoA reductase inhibitors (statins) These agents inhibit the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase. Note the following: Low-density lipoprotein (LDL) reduction of 25%-60% Examples include Atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin Contraindications include hypersensitivity, active liver disease, pregnancy, lactation, coadministration with strong CYP3A4 inhibitors (selected statins) Vitamin B3 Vitamin B3 inhibits very-low-density lipoprotein (VLDL) synthesis. Note the following: LDL reduction of 10% High-density lipoprotein (HDL) increase of 20% Example includes Niacin (nicotinic acid) Contraindications include hypersensitivity, liver disease, active peptic ulcer, severe hypotension, arterial bleeding Fibrates Fibrates enhance lipoprotein lipase, resulting in increased VLDL catabolism, fatty acid oxidation, and triglycerides elimination. They decrease hepatic extraction of free fatty acids. Note the following: LDL reduction of 15% Triglyceride reduction of 35% Examples include Gemfibrozil, fenofibrate, fenofibrate (micronized), fenofibric acid Contraindications include active liver disease, renal disease, primary biliary cirrhosis, gallbladder disease 2-Azetidiones These agents inhibit sterol transporter at brush border and, consequently, intestinal absorption of cholesterol. LDL reduction of 15% Example includes Ezetimibe Contraindications include hypersensitivity, coadministration with statins (if active liver disease) Bile acid sequestrants These agents lower cholesterol and LDL via bile duct sequestration. Note the following: LDL reduction of 15% Examples include Cholestyramine, colesevelam, colestipol Contraindications include biliary/bowel obstruction, serum triglycerides >300-500 mg/dL, history of hypertriglyceridemia-induced pancreatitis

Tracheostomy

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Anatomy of The Upper Limb Joints

TRANSUMBILICAL SINGLE SITE LAP CHOLYCYSTECTOMY

Acute respiratory distress syndrome is characterised by rapid onset dyspnea, bilateral infiltrates on chest x-ray and respiratory failure. This may be due to conditions which directly affect the lung such as pneumonia, aspiration and near drowning. It may also be due to indirect lung injury, as in conditions like sepsis, pancreatitis, trauma and poisoning. The diagnostic criteria of ARDS, often described as the Berlin criteria is discussed in this presentation along with various management aspects of ARDS including ventilation strategies and use of antibiotics and diuretics. Finally prognostic features and alternative strategies are also discussed.

If the artery were severed, blood would flow out unimpeded, although the artery wall would contract in an effort to stop the bleeding. After losing >30% of one's blood volume blood pressure would start dropping, and with less pressure the rate of bleeding would go down. At this stage if the blood loss wasn't replaced the person could die. Losing halve to two thirds of one's blood volume is considered to be fatal even if later on blood transfusion is attempted. One's total blood volume at 70ml/kg is estimated to be between 5 to 7 liters, so that makes a blood loss of between 2,5 to 4,7 L.

About 15 minutes of vibration produces similar results to an hour of conventional resistance therapy, and produces less stress on joints, ligaments and tendons. ~ Detroit Medical Center

In multiple sclerosis, the immune system attacks the protective sheath called myelin, that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause the nerves to deteriorate or become damaged.

Anatomy of The Pharynx

Pediatric Urine Samples Collection

The patient has spasticity in the lower extremities greater than the upper extremities. The hips and knees are flexed and adducted with the ankles extended and internally rotated. When the patient walks both lower extremities are circumducted and the upper extremities are held in a mid or low guard position. This type of gait is usually seen with bilateral periventricular lesions. The legs are more affected than the arms because the corticospinal tract axons that are going to the legs are closest to the ventricles.

Rhabdomyolysis is a condition in which damaged skeletal muscle (Ancient Greek: rhabdomyo-) tissue breaks down rapidly (Greek –lysis). This damage may be caused by physical (e.g. crush injury), chemical, or biological factors. Breakdown products of damaged muscle cells are released into the bloodstream; some of these, such as the protein myoglobin, are harmful to the kidney and may lead to kidney dysfunction. The severity of the symptoms (which may include muscle pains, vomiting and confusion) depends on the extent of the muscle damage, and whether kidney failure develops. The mainstay of treatment is generous intravenous fluids, but could include dialysis or hemofiltration.

Rhabdomyolysis and its complications are significant problems for those injured in disasters such as earthquakes and bombing. Relief efforts in areas struck by earthquakes often include medical teams with skills and equipment for treatment of survivors with rhabdomyolysis. The disease and its mechanisms were first fully elucidated during the Blitz of London in 1941.

Watch that video to know if it is safe to have oral sex or not

Each person's knee is different. This is why UC San Diego Health offers several surgical options for knee replacements to tailor care to each person's injury and health. Each surgical approach has benefits for the right surgical candidate. Our surgeons can discuss what option is most appropriate for each person.

To learn more about knee replacement options at UC San Diego Health, visit:
https://health.ucsd.edu/specia....lties/orthopedics/jo

Francis Gonzales, MD, is a board-certified orthopedic surgeon who specializes in adult hip and knee joint replacement surgery. Learn more about Dr. Gonzales: https://providers.ucsd.edu/det....ails/11935/orthopedi

UC San Diego Health is repeatedly ranked among the nation's best in orthopedic care by U.S. News & World Report. We are also a Blue Distinction Center recognized for our treatment expertise and better overall patient results for knee replacement, as well as a designated Center of Excellence for orthopedic care by Optum. This means you'll receive expert, safe and cost-effective care.

UC San Diego Health's orthopedic surgeons are the first and only in San Diego to offer customized knee replacements with the ROSA knee system — for a faster recovery and more natural feeling knee. Talk to one of our surgeons about whether a ROSA knee replacement is right for you. https://health.ucsd.edu/specia....lties/orthopedics/jo#a

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Ellis demonstrates how to administer an intradermal, subcutaneous, and intramuscular injection.

Our Critical Nursing Skills video tutorial series is taught by Ellis Parker MSN, RN-BC, CNE, CHS and intended to help RN and PN nursing students study for your nursing school exams, including the ATI, HESI and NCLEX.

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00:00 What to expect
00:20 Intradermal injections
00:35 Cleaning site
00:54 Explaining bevel up
1:40 Inserting needle
2:00 Injecting medication
2:16 Withdrawing needle
2:29 Subcutaneous Injections
2:39 Selecting site for subcutaneous injections
3:08 Cleaning subcutaneous injections site
3:18 Pinching subcutaneous injections site
3:30 Inserting needle subcutaneous injections
4:13 Injecting medication subcutaneous injections
4:23 Post injection
4:36 Intramuscular injection
4:54 Locating intramuscular injection site
5:18 Cleaning intramuscular injection site
5:38 Inserting needle intramuscular injection
6:28 Anchoring needle intramuscular injection
6:44 Injecting medication intramuscular injection
6:55 Withdrawing needle intramuscular injection
7:05 Disposing of needle
7:43 Cleaning site
8:00 Displacing with Z-track
8:10 Inserting needle
8:23 Releasing tissue

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This video: Rhomboid muscle strain and spasm causes upper back pain between the shoulder blades. Some patients describe the muscle spasms and discomfort as knots in the back. Early treatment is important to speed healing and recovery. Ice therapy for the first few days followed by moist heat can help relieve symptoms.Oct 12, 2015

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