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Aplastic anemia is a hematopoietic disorder caused due to T lymphocyte mediated destruction of stem cells resulting in pancytopenia with a cellular bone marrow and normal cell cytogenetics. The causes of aplastic anaemia may be inherited or acquired. The causes and the diagnostic approach, along with spectrum of severity of this disorder is discussed in this presentation. A detailed discussion of the management options, along with pharmacological therapy and supportive therapy in these cases is also discussed. The treatment options include, in addition to a stem cell transplant, anti-thymocyte globulin, cyclosporine, methyprednisolone and eltrombopag (for patients who have failed treatment on combined modality therapy with ATG and cyclosporine)
Although your body may harbor the bacteria that cause tuberculosis, your immune system usually can prevent you from becoming sick. For this reason, doctors make a distinction between: Latent TB. In this condition, you have a TB infection, but the bacteria remain in your body in an inactive state and cause no symptoms. Latent TB, also called inactive TB or TB infection, isn't contagious. It can turn into active TB, so treatment is important for the person with latent TB and to help control the spread of TB. An estimated 2 billion people have latent TB. Active TB. This condition makes you sick and can spread to others. It can occur in the first few weeks after infection with the TB bacteria, or it might occur years later. Signs and symptoms of active TB include: Coughing that lasts three or more weeks Coughing up blood Chest pain, or pain with breathing or coughing Unintentional weight loss Fatigue Fever Night sweats
Patients are generally placed in a supine position with the head in an extended position. As noted above, Gardner-Wells tongs can be used for additional cervical traction. The hands can also be tied downward to increase the operative exposure. Once the surgical site is properly prepared with cleansing material, the appropriate surgical level is identified with intraoperative radiographs. A scalpel is used to make a linear longitudinal incision just medial to the body of the sternocleidomastoid muscle. The incision is made long enough to include at least 2 vertebral levels if a 1-level discectomy is being performed. Alternatively, transverse skin incisions over the targeted vertebral level can also be performed. The platysmal muscle is identified and incised. The platysmal incision can be extended if a multilevel decompression is the surgical aim. Extensive subplatysmal dissection is performed to reduce retraction injury.
They might not sound very life threatening, but a blood clot that develops in the deep veins of your leg, if left untreated and unable to dissolve of its own volition, may detach and travel to your lungs, causing a pulmonary embolism (or PE). In most cases, a leg blood clot will form due to lengthy periods of travel, for example if you remain immobile in cramped spaces—such as an airplane or bus—with few opportunities to stretch your legs or get up and walk around. Here are ten signs that you may have a dangerous blood clot in your leg
Johns Hopkins Children’s Center Surgeon-in-Chief David Hackam provides information about general pediatric surgery and when it is time to see a general pediatric surgeon. #PediatricSurgery #JohnsHopkins
For more information on general pediatric surgery at Johns Hopkins Children's Center, visit https://www.hopkinsmedicine.or....g/johns-hopkins-chil
FAQ's
0:02 What is a general pediatric surgeon?
0:31 When is it time to see a pediatric surgeon?
1:02 What are some of the most common surgical problems seen by general pediatric surgeons?
1:43 Describe research being done in the field.
2:15 Why choose Johns Hopkins Children's Center for general pediatric surgery?
Bell's palsy is a form of facial paralysis resulting from damage or trauma to the facial nerves. The facial nerve-also called the 7th cranial nerve-travels through a narrow, bony canal (called the Fallopian canal) in the skull, beneath the ear, to the muscles on each side of the face. For most of its journey, the nerve is encased in this bony shell. Each facial nerve directs the muscles on one side of the face, including those that control eye blinking and closing, and facial expressions such as smiling and frowning. Additionally, the facial nerve carries nerve impulses to the lacrimal or tear glands, the saliva glands, and the muscles of a small bone in the middle of the ear called the stapes. The facial nerve also transmits taste sensations from the tongue. When Bell's palsy occurs, the function of the facial nerve is disrupted, causing an interruption in the messages the brain sends to the facial muscles. This interruption results in facial weakness or paralysis. Bell's palsy is named for Sir Charles Bell, a 19th century Scottish surgeon who described the facial nerve and its connection to the condition. The disorder, which is not related to stroke, is the most common cause of facial paralysis. Generally, Bell's palsy affects only one of the paired facial nerves and one side of the face, however, in rare cases, it can affect both sides.
Eric knew he needed help when an old knee injury began worsening over the course of time and was significantly affecting his quality of life. That’s when he turned to his hometown orthopedic experts at Mayo Clinic Health System in Mankato, who recommended a total knee replacement. After overcoming some initial fears, Eric decided it was time to have the operation — a fuller and more active life with his family depended on it.
giant systolic pulsations, known as C-V waves, were noticeable during jugular venous examination of a 33-year-old woman who had tricuspid-valve endocarditis. In video 2, transthoracic echocardiography revealed severe tricuspid regurgitation.
Empyema can develop after you have pneumonia. Many different types of bacteria may cause pneumonia, but the two most common are Streptococcus pneumoniae and Staphylococcus aureus. Occasionally, empyema may happen after you've had surgery on your chest. Medical instruments can transfer bacteria into your pleural cavity